Project1148 project protocol

Drug Study: Effects of Opioids   (2020)

Bogue MA




Project protocol - Contents

Procedures

Procedure 1: Morphine Lethality Assessment

Procedure PDF:
 

Definitions & Abbreviations: PVDF (polyvinylidene fluoride): Sensor pads for bottom of each cage; USB DAQ: Universal serial bus data acquisition module


Reagents and solutions

  • Morphine (NIH-NIDA drug supply)
  • Haemo-Sol
  • Ethanol

References

Primary References

Bubier JA, He H, Philip VM, Roy T, Hernandez CM, Bernat R, Donohue KD, O'Hara BF, Chesler EJ. Genetic variation regulates opioid-induced respiratory depression in mice. Sci Rep. 2020 Sep 11;10(1):14970. doi: 10.1038/s41598-020-71804-2.   PubMed 32917924     FullText