Nadeau1: Diet-induced obesity survey in C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (males) (2008)

Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004 Apr 16;304(5669):445-8. Epub 2004 Mar 18.   PubMed 15031436  


       
Nadeau1 downloads
• Download Nadeau1 project data set     one row per animal, one column per trait
• Download Nadeau1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Joseph H Nadeau       Case Western Reserve University School of Medicine Cleveland, OH
Annie E Hill       Case Western Reserve University School of Medicine Cleveland, OH
ContactJoseph H Nadeau     jhn4@case.edu     Lab web site
AcknowledgementsFunding provided by NIH RR12305
Project type Phenotype strain survey data set
MPD identifiersNadeau1     MPD:283
Data changelog No updates/corrections.       Initial release date: 06/2008.
Formatted citation
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Animals were weighed at baseline and then again after being fed a high fat, high sucrose diet for 12 wks. (The term "high-fat diet" is used in measurement listings to allow these data to be grouped with other high-fat diet studies).

Summary of procedures that were conducted
• body weight Baseline vs. high-fat diet for 12wks.
Mice: B6.A consomic   24 strains including progenitors   ♂   age 5, 17 wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Nadeau1 28301 body weight high-fat diet body weight   [g]     baseline    after 12wks on diet    Δchange B6.A consomic w/par 24 m 5wks N=18
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