MPD: Data set: Mooney2

Mooney-Leber S, Gould TJ With: Zeid D, Garcia-Trevizo P, Seemiller LR, Peltz G

Mooney2 downloads
• Download Mooney2 project data set animal data, as uploaded
• Download Mooney2 animal data matrix with factor-related expansion applied as necessary
• Download Mooney2 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Mooney2 measures:

Investigators	Sean Mooney-Leber Pennsylvania State University, University Park, PA Thomas J Gould Pennsylvania State University, University Park, PA
Participants	Zeid D, Garcia-Trevizo P, Seemiller LR, Peltz G
Contact	Sean Mooney-Leber sxm1302@psu.edu Lab web site
Part of a series:	• Cerebellum and hippocampus acetylcholinesterase activity see Mooney1 • Nicotine effects on fear conditioning (this project) Mooney2
Project type	Phenotype strain survey data set
MPD identifiers	Mooney2 MPD:1010
Data changelog	This project has not yet been released.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Experimental groups in this study:
• Nicotine 0 mg/kg/day • Nicotine 12 mg/kg/day • Nicotine 18 mg/kg/day

Procedures conducted:

• fear conditioning test

Percent freezing for training and testing in both contextual and cued fear conditioning.

Mice: inbred 21 strains ♂ age 8-12wks 3 experimental groups

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Mooney2:2	Mooney2	fear conditioning test	nicotine	percent freezing during the initial 2 min of training [%] baseline 110079 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10

Mooney2:5	Mooney2	fear conditioning test	nicotine	percent freezing during the 2 min period inbetween CS-US exposures [%] immediate 110082 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10

Mooney2:8	Mooney2	fear conditioning test	nicotine	percent freezing during a context testing trial [%] context 110085 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10

Mooney2:11	Mooney2	fear conditioning test	nicotine	percent freezing during a 3 min PreCS exposure in a novel context [%] precs 110088 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10

Mooney2:14	Mooney2	fear conditioning test	nicotine	percent freezing during a 3 min CS exposure in a novel context [%] cs 110091 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10