McMullan4: Body weight and composition after voluntary exercise in females of 13 Collaborative Cross strains of mice (2018)

McMullan RC, Ferris MT, Bell TA, Menachery VD, Baric RS, Hua K, Pomp D, Smith-Ryan AE, de Villena FP. CC002/Unc females are mouse models of exercise-induced paradoxical fat response. Physiol Rep. 2018 Jun;6(12):e13716. doi: 10.14814/phy2.13716.   PubMed 29924460  


       
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Participants Rachel C McMullan       University of North Carolina Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina Chapel Hill, NC
With: Ferris MT, Bell TA, Menachery VD, Baric RS, Hua K, Pomp D, Smith-Ryan AE
ContactFernando Pardo-Manuel de Villena     fernando@med.unc.edu     Lab web site
AcknowledgementsFunding provided by NIH DK056350, AI100625, AI109761, AG049092, MH100241, DK05350, Al100625
Project type Phenotype strain survey data set
MPD identifiersMcMullan4     MPD:613
Data changelog No updates/corrections.       Initial release date: 07/2018.
Formatted citation
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Female mice (n=173 total mice; ~9 months +/- 4 weeks) from 13 CC strains were assessed before and after two weeks of voluntary exercise (running wheel accessibility) for body weight and composition as well as activity levels and food intake.

Summary of procedures that were conducted
• body weight Body weight before and after 2 weeks of exercise wheel availability.
• MRI Body composition (fat and lean mass) before and after 2 weeks of exercise wheel availability.
• running wheel monitoring Running wheel activity on days 11 and 12.
• intake monitoring Food intake during 2 weeks of exercise wheel availability.
Mice: CC   13 strains   ♀   age 32-40wks   2 cohorts