McMullan1: Body composition and forced endurance in aging females of 50 Collaborative Cross strains of mice (2017)

McMullan RC, Pomp D, Pardo-Manuel de Villena F

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Investigators Rachel C McMullan       University of North Carolina,  Chapel Hill, NC
Daniel Pomp       University of North Carolina,  Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina,  Chapel Hill, NC
ContactFernando Pardo-Manuel de Villena     Lab web site
AcknowledgementsFunding provided by NIH MH100241. Acknowledgements: Kunjie Hua and the Animal Metabolism & Phenotyping Core in NORC (Nutrition Obesity Research Center) University of North Carolina – Chapel Hill (DK05350). System Genetics Core and UNC U19 Project (NIH 1U19Al100625-01) for providing retired breeders.
Project type Phenotype strain survey data set
MPD identifiersMcMullan1     MPD:604
Data changelog No updates/corrections.       Initial release date: 02/2018.
Formatted citation
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Female mice (n = 232) from 50 CC strains were obtained from other experiments or from the System Genetics Core at UNC-Chapel Hill. The female mice in the experiment were retired breeders and varied in life history ad age. Body composition was measured prior to the forced endurance test.

Procedures conducted:
• body weight 
• MRI  Body composition (fat and lean mass and percent).
• treadmill endurance test  Maximal distance is recorded when mouse fails to run.

Mice: CC   50 strains   ♀   age 17-72wks   1 experimental group