McMullan1: Body composition and forced endurance in aging females of 50 Collaborative Cross strains of mice (2017)

McMullan RC, Pomp D, Pardo-Manuel de Villena F

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Investigators Rachel C McMullan       University of North Carolina,  Chapel Hill, NC
Daniel Pomp       University of North Carolina,  Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina,  Chapel Hill, NC
ContactFernando Pardo-Manuel de Villena     Lab web site
AcknowledgementsFunding provided by NIH MH100241. Acknowledgements: Kunjie Hua and the Animal Metabolism & Phenotyping Core in NORC (Nutrition Obesity Research Center) University of North Carolina – Chapel Hill (DK05350). System Genetics Core and UNC U19 Project (NIH 1U19Al100625-01) for providing retired breeders.
Project type Phenotype strain survey data set
MPD identifiersMcMullan1     MPD:604
Data changelog No updates/corrections.       Initial release date: 02/2018.
Formatted citation
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Female mice (n = 232) from 50 CC strains were obtained from other experiments or from the System Genetics Core at UNC-Chapel Hill. The female mice in the experiment were retired breeders and varied in life history ad age. Body composition was measured prior to the forced endurance test.

Summary of procedures that were conducted
• body weight
• MRI Body composition (fat and lean mass and percent).
• treadmill endurance test Maximal distance is recorded when mouse fails to run.
Mice: CC   50 strains   ♀   age 17-72wks   1 experimental group