| Institutional authorship |
Jackson Laboratory
|
| Investigators |
Yan Yang The Jackson Laboratory, Bar Harbor, ME |
| Participants | Yang Y, Rodriguez T |
| Contact | Yan Yang yan.yang@jax.org
|
| Affiliated Center | JAX In Vivo Services |
| One-strain study | |
| MPD identifiers | Jaxwest8 MPD:328 |
| No updates/corrections. Initial release date: 06/2009. | |
|
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Purpose: The objective of this study was to assess the therapeutic potential of a novel compound (L-DOPA) to inhibit the onset and progression of cell loss and development of Parkinsonian pathology in an acute model of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson Disease using using 9-wk-old C57BL/6J male mice.
By posting this data, JAX® In Vivo Services contributes to community research resources and fulfills an agreement with clients to make normative data public.
Investigator's notes and website:
Compound evaluation services: Chronic MPTP Model of Parkinson’s Disease
Available download:
Data: Jaxwest8.xls