Jaxwest8: Assessment of novel compounds (L-DOPA) to inhibit the onset and progression of Parkinsonian pathology in an acute model of Parkinson's Disease using C57BL/6J male mice (2009)

Jackson Laboratory   Yan Yang   With: Yang Y, Rodriguez T

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Institutional authorship Jackson Laboratory     Lab web site
Investigators Yan Yang       The Jackson Laboratory,  Bar Harbor, ME
Participants Yang Y, Rodriguez T
ContactYan Yang     yan.yang@jax.org     Lab web site
Affiliated CenterJAX In Vivo Services
Project type One-strain study
MPD identifiersJaxwest8     MPD:328
Data changelog No updates/corrections.       Initial release date: 06/2009.
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Purpose: The objective of this study was to assess the therapeutic potential of a novel compound (L-DOPA) to inhibit the onset and progression of cell loss and development of Parkinsonian pathology in an acute model of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson Disease using using 9-wk-old C57BL/6J male mice.

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Investigator's notes and website:

Compound evaluation services: Chronic MPTP Model of Parkinson’s Disease

Available download:  


Data: Jaxwest8.xls