ITP2018 compounds

Interventions Testing Program: Lifespan effects in UM-HET3 mice treated with fisetin and SG1002   (2024)

Miller RA, Strong R, Korstanje R, Harrison DE, Rosenthal NA


To see how compounds are proposed by research community members and reviewed by NIA, see Application Instructions

Studied compounds:


fisetin: A senolytic compound that may play an important role in mediating the effects of senescent cells on the pathophysiology of aging. [Wikipedia article]

SG1002: Slowly releases hydrogen sulfide which has numerous beneficial biological effects, including lifespan extension in C. elegans.