| Supplementary data | ||||
group |
tag_name |
descriptions |
units |
column_name |
Per-animal:
vehicle |
bw
1 |
body weight, post-vehicle treatment day 1 | g |
bw1_vehicle |
bw
2 |
body weight, post-vehicle treatment day 2 | g |
bw2_vehicle |
|
bw
3 |
body weight, post-vehicle treatment day 3 | g |
bw3_vehicle |
|
bw
4 |
body weight, post-vehicle treatment day 4 | g |
bw4_vehicle |
|
bw
5 |
body weight, post-vehicle treatment day 5 | g |
bw5_vehicle |
|
bw
6 |
body weight, post-vehicle treatment day 6 | g |
bw6_vehicle |
|
bw
7 |
body weight, post-vehicle treatment day 7 | g |
bw7_vehicle |
|
bw
8 |
body weight, post-vehicle treatment day 8 | g |
bw8_vehicle |
|
bw
9 |
body weight, post-vehicle treatment day 9 | g |
bw9_vehicle |
|
bw
10 |
body weight, post-vehicle treatment day 10 | g |
bw10_vehicle |
|
Per-animal:
DB289
|
bw
1
with
Tx |
body weight, post-DB289 treatment day 1 | g |
bw1_DB289 |
bw
2
with
Tx |
body weight, post-DB289 treatment day 2 | g |
bw2_DB289 |
|
bw
3
with
Tx |
body weight, post-DB289 treatment day 3 | g |
bw3_DB289 |
|
bw
4
with
Tx |
body weight, post-DB289 treatment day 4 | g |
bw4_DB289 |
|
bw
5
with
Tx |
body weight, post-DB289 treatment day 5 | g |
bw5_DB289 |
|
bw
6
with
Tx |
body weight, post-DB289 treatment day 6 | g |
bw6_DB289 |
|
bw
7
with
Tx |
body weight, post-DB289 treatment day 7 | g |
bw7_DB289 |
|
bw
8
with
Tx |
body weight, post-DB289 treatment day 8 | g |
bw8_DB289 |
|
bw
9
with
Tx |
body weight, post-DB289 treatment day 9 | g |
bw9_DB289 |
|
bw
10
with
Tx |
body weight, post-DB289 treatment day 10 | g |
bw10_DB289 |
|
Strain mean: DB289/vehicle (fold change) |
BW |
fold change across cohorts for body weight change over testing period, control and DB289 | ratio |
bw_change_fold |
ALT |
fold change across cohorts for alanine aminotransferase (serum ALT), control and DB289 | ratio |
ALT_fold |
|
BUN |
fold change across cohorts for blood urea nitrogen (serum BUN), control and DB289 | ratio |
BUN_fold |
|
CREA
(serum) |
fold change across cohorts for creatinine (serum CREA), control and DB289 | ratio |
serum_CREA_fold |
|
urine
volume |
fold change across cohorts for urine volume, control and DB289 | ratio |
urine_vol_fold |
|
CREA
(urine) |
fold change across cohorts for creatinine (urine CREA), control and DB289 | ratio |
urine_CREA_fold |
|
KIM1 |
fold change across cohorts for urine kidney injury molecule 1 (KIM-1), control and DB289 | ratio |
urine_KIM1_fold |
|
kidney
weight |
fold change across cohorts for total kidney weight as percent of body weight, control and DB289 | ratio |
pctKW_BW_fold |
|
liver
weight |
fold change across cohorts for liver weight as percent of body weight, control and DB289 | ratio |
pctLW_BW_fold |
|
To download supplementary data: Harrill2_suppdata.xls view excel file