Hallgrimsson1: Facial shape and allometry in a Diversity Outbred (DO) mouse population (2020)

Katz DC, Aponte JD, Liu W, Green RM, Mayeux JM, Pollard KM, Pomp D, Munger SC, Murray SA, Roseman CC, Percival CJ, Cheverud J, Marcucio RS, Hallgrímsson B. Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes. PLoS One. 2020;15(6):e0233377. doi: 10.1371/journal.pone.0233377. Epub 2020 Jun 5.   PubMed 32502155     FullText


         
Facial shape coordinate data were collected on 22 three-dimensional landmarks in DO mice based on mean landmark position (centroid). Data were collected from seven DO generations. Genotypes are available at DODB (search for Hallgrimsson).

Experimental groups in this study:
• baseline    

Procedures conducted:
• body weight 
• bone dimensions  3D, craniofacial landmark coordinates based on centroid.

Hallgrimsson1 downloads
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Investigators David C Katz       University of Calgary,  Calgary, AB CANADA
Benedikt Hallgrimsson       University of Calgary,  Calgary, AB CANADA
Participants Aponte JD, Liu W, Green RM, Mayeux JM, Pollard KM, Pomp D, Munger SC, Murray SA, Roseman CC, Percival CJ, Cheverud J, Marcucio RS
ContactBenedikt Hallgrimsson     bhallgri@ucalgary.ca     Lab web site
Funding Provided ByNIH DE020054, DE019638, DE021708, DK076050, DK087346, DK056350, ES024485; National Sciences and Engineering Research Council (238992-17); March of Dimes (414-01); Alberta Innovates Health Solutions; Alberta Children’s Hospital Research Institute
Project type Phenotype strain survey data set
MPD identifiersHallgrimsson1     MPD:1016
Data changelog No updates/corrections.       Initial release date: 07/2020.
Formatted citation
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Mice: DO population   ♀♂   age 8-60 wks   1 experimental group

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Procedure / Protocol
Treatment
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No. of Strains
Sex
Age
    Hallgrimsson1 body weight (none) body weight   [g]  bw   110550     DO population both 8-60wks N=569
    Hallgrimsson1 bone dimensions (none) square root of the summed squared distance of each 3D landmark from the mean landmark position (centroid) of that specimen  centroid   110551     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) midline superior incisor, right side, x coordinate   [mm]  lm1_x   110552     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) midline superior incisor, right side, y coordinate   [mm]  lm1_y   110553     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) midline superior incisor, right side, z coordinate   [mm]  lm1_z   110554     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) anterior most intersection of nasal and premaxilla, right side, x coordinate   [mm]  lm2_x   110555     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) anterior most intersection of nasal and premaxilla, right side, y coordinate   [mm]  lm2_y   110556     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) anterior most intersection of nasal and premaxilla, right side, z coordinate   [mm]  lm2_z   110557     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) anterior margin of incisive foramen, right side, x coordinate   [mm]  lm3_x   110558     DO population both 8-60wks N=574
    Hallgrimsson1 bone dimensions (none) anterior margin of incisive foramen, right side, y coordinate   [mm]  lm3_y   110559     DO population both 8-60wks N=574
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