MPD: Data set: Hallgrimsson1

Hallgrimsson1: Facial shape and allometry in a Diversity Outbred (DO) mouse population (2020)

Katz DC, Aponte JD, Liu W, Green RM, Mayeux JM, Pollard KM, Pomp D, Munger SC, Murray SA, Roseman CC, Percival CJ, Cheverud J, Marcucio RS, Hallgrímsson B. Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes. PLoS One. 2020;15(6):e0233377. doi: 10.1371/journal.pone.0233377. Epub 2020 Jun 5. PubMed 32502155 FullText

Facial shape coordinate data were collected on 22 three-dimensional landmarks in DO mice based on mean landmark position (centroid). Data were collected from seven DO generations. Genotypes are available at DODB (search for Hallgrimsson).

Experimental groups in this study:
• baseline

Procedures conducted:

• body weight
• bone dimensions		3D, craniofacial landmark coordinates based on centroid.

Hallgrimsson1 downloads
• Download Hallgrimsson1 project data set animal data, as uploaded
• Download Hallgrimsson1 animal data matrix with factor-related expansion applied as necessary
• Download Hallgrimsson1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Hallgrimsson1 measures:

MA:0000316 cranium
MA:0000345 oral region cartilage/bone
MA:0000349 incisor
MA:0001492 maxilla alveolar process
MA:0001497 zygomatic bone
MA:0002796 frontal suture
MP:0000455 abnormal maxilla morphology
MP:0001259 abnormal body weight
MP:0002116 abnormal craniofacial bone morphology
MP:0030137 abnormal upper incisor morphology
MP:0030502 abnormal incisive foramen morphology
VT:0000102 nasal bone morphology trait
VT:0000438 skull morphology trait
VT:0000455 maxilla morphology trait
VT:0001259 body mass
VT:0002116 craniofacial bone morphology trait
VT:0002820 premaxillary bone morphology trait
VT:0002835 cranial suture morphology trait
VT:0005270 zygomatic bone morphology trait
VT:0005358 incisor morphology trait

Investigators	David C Katz University of Calgary, Calgary, AB CANADA Benedikt Hallgrimsson University of Calgary, Calgary, AB CANADA
Participants	Aponte JD, Liu W, Green RM, Mayeux JM, Pollard KM, Pomp D, Munger SC, Murray SA, Roseman CC, Percival CJ, Cheverud J, Marcucio RS
Contact	Benedikt Hallgrimsson bhallgri@ucalgary.ca Lab web site
Funding Provided By	NIH DE020054, DE019638, DE021708, DK076050, DK087346, DK056350, ES024485; National Sciences and Engineering Research Council (238992-17); March of Dimes (414-01); Alberta Innovates Health Solutions; Alberta Children’s Hospital Research Institute
Project type	Phenotype strain survey data set
MPD identifiers	Hallgrimsson1 MPD:1016
Data changelog	No updates/corrections. Initial release date: 07/2020.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Mice: DO population ♀♂ age 8-60 wks 1 experimental group

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)

Hallgrimsson1:4	Hallgrimsson1	body weight	(none)	body weight [g] bw 110550	DO population	both	8-60wks	N=569

Hallgrimsson1:5	Hallgrimsson1	bone dimensions	(none)	square root of the summed squared distance of each 3D landmark from the mean landmark position (centroid) of that specimen centroid 110551	DO population	both	8-60wks	N=574

Hallgrimsson1:6	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, right side, x coordinate [mm] lm1_x 110552	DO population	both	8-60wks	N=574

Hallgrimsson1:7	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, right side, y coordinate [mm] lm1_y 110553	DO population	both	8-60wks	N=574

Hallgrimsson1:8	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, right side, z coordinate [mm] lm1_z 110554	DO population	both	8-60wks	N=574

Hallgrimsson1:9	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, right side, x coordinate [mm] lm2_x 110555	DO population	both	8-60wks	N=574

Hallgrimsson1:10	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, right side, y coordinate [mm] lm2_y 110556	DO population	both	8-60wks	N=574

Hallgrimsson1:11	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, right side, z coordinate [mm] lm2_z 110557	DO population	both	8-60wks	N=574

Hallgrimsson1:12	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, right side, x coordinate [mm] lm3_x 110558	DO population	both	8-60wks	N=574

Hallgrimsson1:13	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, right side, y coordinate [mm] lm3_y 110559	DO population	both	8-60wks	N=574

Hallgrimsson1:14	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, right side, z coordinate [mm] lm3_z 110560	DO population	both	8-60wks	N=574

Hallgrimsson1:15	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, right side, x coordinate [mm] lm4_x 110561	DO population	both	8-60wks	N=574

Hallgrimsson1:16	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, right side, y coordinate [mm] lm4_y 110562	DO population	both	8-60wks	N=574

Hallgrimsson1:17	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, right side, z coordinate [mm] lm4_z 110563	DO population	both	8-60wks	N=574

Hallgrimsson1:18	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, right side, x coordinate [mm] lm5_x 110564	DO population	both	8-60wks	N=574

Hallgrimsson1:19	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, right side, y coordinate [mm] lm5_y 110565	DO population	both	8-60wks	N=574

Hallgrimsson1:20	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, right side, z coordinate [mm] lm5_z 110566	DO population	both	8-60wks	N=574

Hallgrimsson1:21	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, right side, x coordinate [mm] lm6_x 110567	DO population	both	8-60wks	N=574

Hallgrimsson1:22	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, right side, y coordinate [mm] lm6_y 110568	DO population	both	8-60wks	N=574

Hallgrimsson1:23	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, right side, z coordinate [mm] lm6_z 110569	DO population	both	8-60wks	N=574

Hallgrimsson1:24	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, right side, x coordinate [mm] lm7_x 110570	DO population	both	8-60wks	N=574

Hallgrimsson1:25	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, right side, y coordinate [mm] lm7_y 110571	DO population	both	8-60wks	N=574

Hallgrimsson1:26	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, right side, z coordinate [mm] lm7_z 110572	DO population	both	8-60wks	N=574

Hallgrimsson1:27	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, right side, x coordinate [mm] lm8_x 110573	DO population	both	8-60wks	N=574

Hallgrimsson1:28	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, right side, y coordinate [mm] lm8_y 110574	DO population	both	8-60wks	N=574

Hallgrimsson1:29	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, right side, z coordinate [mm] lm8_z 110575	DO population	both	8-60wks	N=574

Hallgrimsson1:30	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, right side, x coordinate [mm] lm9_x 110576	DO population	both	8-60wks	N=574

Hallgrimsson1:31	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, right side, y coordinate [mm] lm9_y 110577	DO population	both	8-60wks	N=574

Hallgrimsson1:32	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, right side, z coordinate [mm] lm9_z 110578	DO population	both	8-60wks	N=574

Hallgrimsson1:33	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, right side, x coordinate [mm] lm10_x 110579	DO population	both	8-60wks	N=574

Hallgrimsson1:34	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, right side, y coordinate [mm] lm10_y 110580	DO population	both	8-60wks	N=574

Hallgrimsson1:35	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, right side, z coordinate [mm] lm10_z 110581	DO population	both	8-60wks	N=574

Hallgrimsson1:36	Hallgrimsson1	bone dimensions	(none)	nasion, x coordinate [mm] lm11_x 110582	DO population	both	8-60wks	N=574

Hallgrimsson1:37	Hallgrimsson1	bone dimensions	(none)	nasion, y coordinate [mm] lm11_y 110583	DO population	both	8-60wks	N=574

Hallgrimsson1:38	Hallgrimsson1	bone dimensions	(none)	nasion, z coordinate [mm] lm11_z 110584	DO population	both	8-60wks	N=574

Hallgrimsson1:39	Hallgrimsson1	bone dimensions	(none)	midline endocranial point at the intersection of the frontal bones and the anterior most point of the cribriform plate of the ethmoid, generally placed on the frontal bone, x coordinate [mm] lm12_x 110585	DO population	both	8-60wks	N=574

Hallgrimsson1:40	Hallgrimsson1	bone dimensions	(none)	midline endocranial point at the intersection of the frontal bones and the anterior most point of the cribriform plate of the ethmoid, generally placed on the frontal bone, y coordinate [mm] lm12_y 110586	DO population	both	8-60wks	N=574

Hallgrimsson1:41	Hallgrimsson1	None	(none)	midline endocranial point at the intersection of the frontal bones and the anterior most point of the cribriform plate of the ethmoid, generally placed on the frontal bone, z coordinate [mm] lm12_z 110587	DO population	both	8-60wks	N=574

Hallgrimsson1:42	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, left side, x coordinate [mm] lm13_x 110588	DO population	both	8-60wks	N=574

Hallgrimsson1:43	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, left side, y coordinate [mm] lm13_y 110589	DO population	both	8-60wks	N=574

Hallgrimsson1:44	Hallgrimsson1	bone dimensions	(none)	midline superior incisor, left side, z coordinate [mm] lm13_z 110590	DO population	both	8-60wks	N=574

Hallgrimsson1:45	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, left side, x coordinate [mm] lm14_x 110591	DO population	both	8-60wks	N=574

Hallgrimsson1:46	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, left side, y coordinate [mm] lm14_y 110592	DO population	both	8-60wks	N=574

Hallgrimsson1:47	Hallgrimsson1	bone dimensions	(none)	anterior most intersection of nasal and premaxilla, left side, z coordinate [mm] lm14_z 110593	DO population	both	8-60wks	N=574

Hallgrimsson1:48	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, left side, x coordinate [mm] lm15_x 110594	DO population	both	8-60wks	N=574

Hallgrimsson1:49	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, left side, y coordinate [mm] lm15_y 110595	DO population	both	8-60wks	N=574

Hallgrimsson1:50	Hallgrimsson1	bone dimensions	(none)	anterior margin of incisive foramen, left side, z coordinate [mm] lm15_z 110596	DO population	both	8-60wks	N=574

Hallgrimsson1:51	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, left side, x coordinate [mm] lm16_x 110597	DO population	both	8-60wks	N=574

Hallgrimsson1:52	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, left side, y coordinate [mm] lm16_y 110598	DO population	both	8-60wks	N=574

Hallgrimsson1:53	Hallgrimsson1	bone dimensions	(none)	medial maxilla-premaxilla junction, left side, z coordinate [mm] lm16_z 110599	DO population	both	8-60wks	N=574

Hallgrimsson1:54	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, left side, x coordinate [mm] lm17_x 110600	DO population	both	8-60wks	N=574

Hallgrimsson1:55	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, left side, y coordinate [mm] lm17_y 110601	DO population	both	8-60wks	N=574

Hallgrimsson1:56	Hallgrimsson1	bone dimensions	(none)	posterior incisive foramen, left side, z coordinate [mm] lm17_z 110602	DO population	both	8-60wks	N=574

Hallgrimsson1:57	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, left side, x coordinate [mm] lm18_x 110603	DO population	both	8-60wks	N=574

Hallgrimsson1:58	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, left side, y coordinate [mm] lm18_y 110604	DO population	both	8-60wks	N=574

Hallgrimsson1:59	Hallgrimsson1	bone dimensions	(none)	anterior superior alveoli, left side, z coordinate [mm] lm18_z 110605	DO population	both	8-60wks	N=574

Hallgrimsson1:60	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, left side, x coordinate [mm] lm19_x 110606	DO population	both	8-60wks	N=574

Hallgrimsson1:61	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, left side, y coordinate [mm] lm19_y 110607	DO population	both	8-60wks	N=574

Hallgrimsson1:62	Hallgrimsson1	bone dimensions	(none)	posterior superior alveoli, left side, z coordinate [mm] lm19_z 110608	DO population	both	8-60wks	N=574

Hallgrimsson1:63	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, left side, x coordinate [mm] lm20_x 110609	DO population	both	8-60wks	N=574

Hallgrimsson1:64	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, left side, y coordinate [mm] lm20_y 110610	DO population	both	8-60wks	N=574

Hallgrimsson1:65	Hallgrimsson1	bone dimensions	(none)	intersection of frontal suture with orbital rim, left side, z coordinate [mm] lm20_z 110611	DO population	both	8-60wks	N=574

Hallgrimsson1:66	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, left side, x coordinate [mm] lm21_x 110612	DO population	both	8-60wks	N=574

Hallgrimsson1:67	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, left side, y coordinate [mm] lm21_y 110613	DO population	both	8-60wks	N=574

Hallgrimsson1:68	Hallgrimsson1	bone dimensions	(none)	anterior inferior zygomatic, left side, z coordinate [mm] lm21_z 110614	DO population	both	8-60wks	N=574

Hallgrimsson1:69	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, left side, x coordinate [mm] lm22_x 110615	DO population	both	8-60wks	N=574

Hallgrimsson1:70	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, left side, y coordinate [mm] lm22_y 110616	DO population	both	8-60wks	N=574

Hallgrimsson1:71	Hallgrimsson1	bone dimensions	(none)	lateral point along frontal suture, left side, z coordinate [mm] lm22_z 110617	DO population	both	8-60wks	N=574