Dickson1: Incentive salience to reward cues measured by Pavlovian sign-tracking in 5 inbred founder strains of the Collaborative Cross (2015)
Dickson PE, McNaughton KA, Hou L, Anderson LC, Long KH, Chesler EJ. Sex and strain influence attribution of incentive salience to reward cues in mice.
Behav Brain Res. 2015 Oct 1;292:305-15. doi: 10.1016/j.bbr.2015.05.039. Epub 2015 Jun 20.
Sign-tracking and the related phenotype goal-tracking were evaluated under paired and unpaired conditions. The propensity to attribute incentive salience to reward cues, measured by Pavlovian sign-tracking, has been shown previously to be strongly associated with addiction-related traits including cocaine self-administration, impulsivity, novelty reactivity, and novelty preference. The means of sign-tracking and goal-tracking duration have been accessioned for mice under paired and unpaired conditions. The remaining measurements are available in a supplemental download file and are summarized graphically here.
A correlations matrix of most measurements is also available.
Experimental groups in this study:
• None
• None
Procedures conducted:
Experimental groups in this study:
Procedures conducted:
| Sign tracking and goal tracking paradigm with Pavlovian conditioned approach. |
Dickson1 downloads
• Download Dickson1 project data set animal data, as uploaded
• Download Dickson1 animal data matrix with factor-related expansion applied as necessary
• Download Dickson1 strain means, SD, N, etc. one row per strain/sex/measure
• Dickson1 supplementary data
• Download Dickson1 project data set animal data, as uploaded
• Download Dickson1 animal data matrix with factor-related expansion applied as necessary
• Download Dickson1 strain means, SD, N, etc. one row per strain/sex/measure
• Dickson1 supplementary data
Ontology terms mapped to Dickson1 measures:
| Investigators |
Price E Dickson The Jackson Laboratory, Bar Harbor, ME Elissa J Chesler The Jackson Laboratory, Bar Harbor, ME |
| Participants | McNaughton KA, Hou L, Anderson LC, Long KH |
| Contact | Price E Dickson price.dickson@jax.org |
| Affiliated Center | Center for Systems Neurogenetics of Addiction (CSNA) |
| Acknowledgements | Funding provided by NIH DA37927, GM76468; Research Experience for Undergraduates at The Jackson Laboratory (DBI-1262049) |
| Phenotype strain survey data set | |
| MPD identifiers | Dickson1 MPD:546 |
| No updates/corrections. Initial release date: 06/2016. | |
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