Project measure / variable:   Bolivar2   act_shock_1

ID, description, units MPD:63902   act_shock_1   activity (beam breaks) during 2.5 min period of training on day 1   [n]  after 1st shock  
Data set, strains Bolivar2   inbred   8 strains     sex: both     age: 9-20wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Bolivar2 - activity (beam breaks) during 2.5 min period of training on day 1 after 1st shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means83.64   n 91.43   n
Median of the strain means85.64   n 82.69   n
SD of the strain means± 29.341 ± 29.324
Coefficient of variation (CV)0.3508 0.3207
Min–max range of strain means41.822   –   122.0   n 53.33   –   142.3   n
Mean sample size per strain18.0   mice 18.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4374.2422 4374.2422 9.3924 0.0024
strain 7 207381.5267 29625.9324 63.6132 < 0.0001
sex:strain 7 9482.0956 1354.5851 2.9086 0.006
Residuals 272 126675.84 465.72


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 50.4 22.013   18 5.1886 0.4368 23.2, 121.2 -1.13
129S1/SvImJ m 53.33 18.004   18 4.2437 0.3376 23.6, 87.2 -1.3
A/J f 65.69 17.445   18 4.1118 0.2656 42.4, 107.2 -0.61
A/J m 72.02 17.902   18 4.2197 0.2486 36.4, 104.0 -0.66
BALB/cByJ f 122.0 20.473   18 4.8255 0.1678 82.0, 165.2 1.31
BALB/cByJ m 142.3 27.115   18 6.391 0.1905 93.6, 192.8 1.73
C3H/HeJ f 79.44 16.884   18 3.9796 0.2125 45.2, 111.2 -0.14
C3H/HeJ m 74.87 19.978   18 4.7087 0.2668 36.4, 112.8 -0.56
C57BL/6J f 91.84 20.862   18 4.9171 0.2271 52.8, 122.0 0.28
C57BL/6J m 90.51 19.654   18 4.6326 0.2171 48.4, 122.4 -0.03
CBA/J f 106.4 22.465   18 5.295 0.2112 72.8, 164.8 0.78
CBA/J m 105.5 26.795   18 6.3156 0.2541 49.6, 143.2 0.48
DBA/2J f 41.822 15.98   18 3.7664 0.3821 12.8, 72.4 -1.43
DBA/2J m 73.24 30.554   18 7.2017 0.4172 20.4, 127.6 -0.62
FVB/NJ f 111.5 26.589   18 6.267 0.2384 53.2, 152.0 0.95
FVB/NJ m 119.7 15.473   18 3.6471 0.1293 97.6, 156.8 0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 50.4 5.0866 60.4141 40.3859
129S1/SvImJ m 53.3333 5.0866 63.3474 43.3193
A/J f 65.6889 5.0866 75.703 55.6748
A/J m 72.0222 5.0866 82.0363 62.0081
BALB/cByJ f 122.0 5.0866 132.0141 111.9859
BALB/cByJ m 142.3333 5.0866 152.3474 132.3193
C3H/HeJ f 79.4444 5.0866 89.4585 69.4304
C3H/HeJ m 74.8667 5.0866 84.8807 64.8526
C57BL/6J f 91.8444 5.0866 101.8585 81.8304
C57BL/6J m 90.5111 5.0866 100.5252 80.497
CBA/J f 106.3778 5.0866 116.3919 96.3637
CBA/J m 105.4667 5.0866 115.4807 95.4526
DBA/2J f 41.8222 5.0866 51.8363 31.8081
DBA/2J m 73.2444 5.0866 83.2585 63.2304
FVB/NJ f 111.5333 5.0866 121.5474 101.5193
FVB/NJ m 119.6889 5.0866 129.703 109.6748


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 51.8667 3.5968 58.9477 44.7856
A/J both 68.8556 3.5968 75.9366 61.7745
BALB/cByJ both 132.1667 3.5968 139.2477 125.0856
C3H/HeJ both 77.1556 3.5968 84.2366 70.0745
C57BL/6J both 91.1778 3.5968 98.2588 84.0968
CBA/J both 105.9222 3.5968 113.0032 98.8412
DBA/2J both 57.5333 3.5968 64.6144 50.4523
FVB/NJ both 115.6111 3.5968 122.6921 108.5301




  GWAS USING LINEAR MIXED MODELS