Project measure / variable:   GMC17   pip_24

ID, description, units MPD:56615   pip_24   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  24 kHz sound stimulus  
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level 24 kHz sound stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means66.7   dB 63.4   dB
Median of the strain means64.7   dB 49.7   dB
SD of the strain means± 27.4 ± 28.4
Coefficient of variation (CV)0.411 0.448
Min–max range of strain means35.0   –   100   dB 35.0   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1137.5 1137.5 3.6652 0.0573
strain 6 105028.3467 17504.7244 56.4034 < 0.0001
sex:strain 6 1388.5318 231.422 0.7457 0.6136
Residuals 168 52138.6161 310.3489


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 49.4 7.72   16 1.93 0.156 40.0, 70.0 -0.63
129S1/SvImJ m 43.1 8.14   16 2.03 0.189 30.0, 65.0 -0.71
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.21
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.29
C57BL/6J f 64.7 26.2   16 6.54 0.405 30.0, 100.0 -0.07
C57BL/6J m 49.7 16.6   16 4.14 0.334 30.0, 100.0 -0.48
CAST/EiJ f 38.1 6.51   8 2.3 0.171 30.0, 45.0 -1.04
CAST/EiJ m 39.3 9.76   7 3.69 0.248 30.0, 55.0 -0.85
NOD/ShiLtJ f 100.0 0.0   17 0.0 0.0 100.0, 100.0 1.21
NOD/ShiLtJ m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.29
NZO/HlLtJ f 80.0 32.2   16 8.05 0.402 25.0, 100.0 0.48
NZO/HlLtJ m 76.6 35.9   16 8.99 0.47 20.0, 100.0 0.47
WSB/EiJ f 35.0 0.0   2   0.0 0.0 35.0, 35.0 -1.16
WSB/EiJ m 35.0 4.08   4 2.04 0.117 30.0, 40.0 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 49.375 4.4042 58.0697 40.6803
129S1/SvImJ m 43.125 4.4042 51.8197 34.4303
A/J f 100.0 4.4042 108.6947 91.3053
A/J m 100.0 4.4042 108.6947 91.3053
C57BL/6J f 64.6875 4.4042 73.3822 55.9928
C57BL/6J m 49.6875 4.4042 58.3822 40.9928
CAST/EiJ f 38.125 6.2285 50.4211 25.8289
CAST/EiJ m 39.2857 6.6585 52.4308 26.1406
NOD/ShiLtJ f 100.0 4.2727 108.4351 91.5649
NOD/ShiLtJ m 100.0 4.4042 108.6947 91.3053
NZO/HlLtJ f 80.0 4.4042 88.6947 71.3053
NZO/HlLtJ m 76.5625 4.4042 85.2572 67.8678
WSB/EiJ f 35.0 12.4569 59.5922 10.4078
WSB/EiJ m 35.0 8.8084 52.3893 17.6107


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.25 3.1142 52.3981 40.1019
A/J both 100.0 3.1142 106.1481 93.8519
C57BL/6J both 57.1875 3.1142 63.3356 51.0394
CAST/EiJ both 38.7054 4.5588 47.7052 29.7055
NOD/ShiLtJ both 100.0 3.0681 106.057 93.943
NZO/HlLtJ both 78.2813 3.1142 84.4293 72.1332
WSB/EiJ both 35.0 7.6283 50.0596 19.9404




  GWAS USING LINEAR MIXED MODELS