Project measure / variable:   GMC17   pip_12

ID, description, units MPD:56613   pip_12   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  12 kHz sound stimulus  
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level 12 kHz sound stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means55.2   dB 55.7   dB
Median of the strain means32.5   dB 29.7   dB
SD of the strain means± 32.8 ± 34.5
Coefficient of variation (CV)0.594 0.620
Min–max range of strain means25.0   –   100   dB 28.4   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.3077 4.3077 0.0135 0.9077
strain 6 177975.4379 29662.573 92.9278 < 0.0001
sex:strain 6 846.8518 141.142 0.4422 0.8497
Residuals 168 53625.6224 319.2001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 31.6 6.76   16 1.69 0.214 20.0, 45.0 -0.72
129S1/SvImJ m 28.4 7.0   16 1.75 0.246 20.0, 40.0 -0.79
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.37
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.28
C57BL/6J f 29.1 5.84   16 1.46 0.201 15.0, 35.0 -0.8
C57BL/6J m 29.7 7.18   16 1.8 0.242 20.0, 45.0 -0.75
CAST/EiJ f 32.5 11.3   8 4.01 0.349 20.0, 55.0 -0.69
CAST/EiJ m 28.6 10.3   7 3.89 0.36 15.0, 45.0 -0.79
NOD/ShiLtJ f 91.2 19.9   17 4.82 0.218 45.0, 100.0 1.1
NOD/ShiLtJ m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.28
NZO/HlLtJ f 77.2 36.2   16 9.06 0.469 15.0, 100.0 0.67
NZO/HlLtJ m 74.5 39.1   16 9.79 0.525 12.0, 100.0 0.54
WSB/EiJ f 25.0 0.0   2   0.0 0.0 25.0, 25.0 -0.92
WSB/EiJ m 28.8 11.1   4 5.54 0.386 20.0, 45.0 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 31.5625 4.4665 40.3803 22.7447
129S1/SvImJ m 28.4375 4.4665 37.2553 19.6197
A/J f 100.0 4.4665 108.8178 91.1822
A/J m 100.0 4.4665 108.8178 91.1822
C57BL/6J f 29.0625 4.4665 37.8803 20.2447
C57BL/6J m 29.6875 4.4665 38.5053 20.8697
CAST/EiJ f 32.5 6.3166 44.9702 20.0298
CAST/EiJ m 28.5714 6.7528 41.9027 15.2402
NOD/ShiLtJ f 91.1765 4.3332 99.731 82.622
NOD/ShiLtJ m 100.0 4.4665 108.8178 91.1822
NZO/HlLtJ f 77.1875 4.4665 86.0053 68.3697
NZO/HlLtJ m 74.5 4.4665 83.3178 65.6822
WSB/EiJ f 25.0 12.6333 49.9405 0.0595
WSB/EiJ m 28.75 8.9331 46.3856 11.1144


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 30.0 3.1583 36.2351 23.7649
A/J both 100.0 3.1583 106.2351 93.7649
C57BL/6J both 29.375 3.1583 35.6101 23.1399
CAST/EiJ both 30.5357 4.6233 39.663 21.4084
NOD/ShiLtJ both 95.5882 3.1115 101.731 89.4455
NZO/HlLtJ both 75.8438 3.1583 82.0789 69.6086
WSB/EiJ both 26.875 7.7363 42.1478 11.6022




  GWAS USING LINEAR MIXED MODELS