Project measure / variable:   GMC17   pip_6

ID, description, units MPD:56612   pip_6   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  6kHz sound stimulus  
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level 6kHz sound stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means67.1   dB 68.6   dB
Median of the strain means60.6   dB 55.0   dB
SD of the strain means± 21.5 ± 22.5
Coefficient of variation (CV)0.320 0.328
Min–max range of strain means40.0   –   100   dB 48.8   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.4341 3.4341 0.0162 0.8987
strain 6 69992.2894 11665.3816 55.1658 < 0.0001
sex:strain 6 2065.8594 344.3099 1.6282 0.1422
Residuals 168 35525.3676 211.4605


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 60.6 7.93   16 1.98 0.131 50.0, 75.0 -0.3
129S1/SvImJ m 54.1 6.12   16 1.53 0.113 45.0, 65.0 -0.65
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.53
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.39
C57BL/6J f 47.8 7.95   16 1.99 0.166 30.0, 60.0 -0.9
C57BL/6J m 49.4 12.0   16 2.99 0.242 30.0, 70.0 -0.85
CAST/EiJ f 57.5 12.5   8 4.43 0.218 45.0, 80.0 -0.45
CAST/EiJ m 55.0 21.0   7 7.94 0.382 40.0, 100.0 -0.61
NOD/ShiLtJ f 84.4 17.8   17 4.31 0.21 55.0, 100.0 0.8
NOD/ShiLtJ m 97.8 8.75   16 2.19 0.0895 65.0, 100.0 1.3
NZO/HlLtJ f 79.4 26.8   16 6.71 0.338 25.0, 100.0 0.57
NZO/HlLtJ m 75.3 25.6   16 6.4 0.34 35.0, 100.0 0.3
WSB/EiJ f 40.0 14.1   2   10.0 0.354 30.0, 50.0 -1.26
WSB/EiJ m 48.8 7.5   4 3.75 0.154 40.0, 55.0 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 60.625 3.6354 67.802 53.448
129S1/SvImJ m 54.0625 3.6354 61.2395 46.8855
A/J f 100.0 3.6354 107.177 92.823
A/J m 100.0 3.6354 107.177 92.823
C57BL/6J f 47.8125 3.6354 54.9895 40.6355
C57BL/6J m 49.375 3.6354 56.552 42.198
CAST/EiJ f 57.5 5.1413 67.6498 47.3502
CAST/EiJ m 55.0 5.4962 65.8506 44.1494
NOD/ShiLtJ f 84.4118 3.5269 91.3745 77.4491
NOD/ShiLtJ m 97.8125 3.6354 104.9895 90.6355
NZO/HlLtJ f 79.375 3.6354 86.552 72.198
NZO/HlLtJ m 75.3125 3.6354 82.4895 68.1355
WSB/EiJ f 40.0 10.2825 60.2996 19.7004
WSB/EiJ m 48.75 7.2708 63.104 34.396


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 57.3437 2.5706 62.4187 52.2688
A/J both 100.0 2.5706 105.0749 94.9251
C57BL/6J both 48.5937 2.5706 53.6687 43.5188
CAST/EiJ both 56.25 3.763 63.6789 48.8211
NOD/ShiLtJ both 91.1121 2.5325 96.1118 86.1124
NZO/HlLtJ both 77.3437 2.5706 82.4187 72.2688
WSB/EiJ both 44.375 6.2967 56.8059 31.9441




  GWAS USING LINEAR MIXED MODELS