Phenotype measure:   GMC17   click

ID, description, units MPD:56611   click   auditory brainstem response (ABR) threshold, sound pressure level, click stimulus   [dB]   measure
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level, click stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means60.1   dB 59.2   dB
Median of the strain means49.7   dB 42.5   dB
SD of the strain means± 28.0 ± 31.1
Coefficient of variation (CV)0.466 0.527
Min–max range of strain means30.0   –   100   dB 31.2   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 149.5879 149.5879 0.6767 0.4119
strain 6 126312.7299 21052.1216 95.2329 < 0.0001
sex:strain 6 1594.8887 265.8148 1.2025 0.3074
Residuals 168 37137.9858 221.0594


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 49.7 5.31   16 1.33 0.107 40.0, 60.0 -0.37
129S1/SvImJ m 42.5 5.77   16 1.44 0.136 35.0, 55.0 -0.53
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.42
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.31
C57BL/6J f 40.3 5.91   16 1.48 0.147 30.0, 45.0 -0.71
C57BL/6J m 34.1 4.17   16 1.04 0.122 25.0, 40.0 -0.8
CAST/EiJ f 35.0 4.63   8 1.64 0.132 30.0, 45.0 -0.9
CAST/EiJ m 32.9 5.67   7 2.14 0.173 25.0, 40.0 -0.84
NOD/ShiLtJ f 87.9 13.9   17 3.38 0.158 65.0, 100.0 0.99
NOD/ShiLtJ m 98.1 7.5   16 1.88 0.0764 70.0, 100.0 1.25
NZO/HlLtJ f 77.8 30.8   16 7.71 0.396 25.0, 100.0 0.63
NZO/HlLtJ m 75.3 33.5   16 8.37 0.445 25.0, 100.0 0.52
WSB/EiJ f 30.0 7.07   2   5.0 0.236 25.0, 35.0 -1.07
WSB/EiJ m 31.2 2.5   4 1.25 0.08 30.0, 35.0 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 49.6875 3.717 57.0256 42.3494
129S1/SvImJ m 42.5 3.717 49.8381 35.1619
A/J f 100.0 3.717 107.3381 92.6619
A/J m 100.0 3.717 107.3381 92.6619
C57BL/6J f 40.3125 3.717 47.6506 32.9744
C57BL/6J m 34.0625 3.717 41.4006 26.7244
CAST/EiJ f 35.0 5.2567 45.3776 24.6224
CAST/EiJ m 32.8571 5.6196 43.9513 21.763
NOD/ShiLtJ f 87.9412 3.606 95.0602 80.8222
NOD/ShiLtJ m 98.125 3.717 105.4631 90.7869
NZO/HlLtJ f 77.8125 3.717 85.1506 70.4744
NZO/HlLtJ m 75.3125 3.717 82.6506 67.9744
WSB/EiJ f 30.0 10.5133 50.7552 9.2448
WSB/EiJ m 31.25 7.434 45.9262 16.5738


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.0938 2.6283 51.2826 40.9049
A/J both 100.0 2.6283 105.1888 94.8112
C57BL/6J both 37.1875 2.6283 42.3763 31.9987
CAST/EiJ both 33.9286 3.8475 41.5242 26.3329
NOD/ShiLtJ both 93.0331 2.5894 98.145 87.9212
NZO/HlLtJ both 76.5625 2.6283 81.7513 71.3737
WSB/EiJ both 30.625 6.4381 43.3349 17.9151




GWAS analysis not available: At least 12 strains are required