Project measure / variable:   GMC15   PLCR

ID, description, units MPD:56438   PLCR   platelet large cell ratio (PLCR)   [%]  
Data set, strains GMC15   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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GMC15 - platelet large cell ratio (PLCR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.68   % 2.81   %
Median of the strain means2.75   % 2.25   %
SD of the strain means± 1.58 ± 1.66
Coefficient of variation (CV)0.589 0.593
Min–max range of strain means0.967   –   5.15   % 0.975   –   5.28   %
Mean sample size per strain10.2   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8034 0.8034 0.2451 0.6212
strain 7 355.5287 50.7898 15.4925 < 0.0001
sex:strain 7 51.4279 7.3468 2.241 0.0336
Residuals 160 524.5372 3.2784


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.26 0.615   10 0.194 0.488 0.2, 2.0 -0.9
129S1/SvImJ m 0.975 0.852   12 0.246 0.874 0.2, 3.1 -1.1
A/J f 2.88 1.84   10 0.581 0.638 1.9, 8.0 0.13
A/J m 2.03 0.363   12 0.105 0.178 1.6, 2.8 -0.47
C57BL/6J f 2.61 1.18   10 0.373 0.452 1.0, 5.3 -0.04
C57BL/6J m 2.16 0.483   12 0.14 0.224 1.4, 3.0 -0.39
CAST/EiJ f 0.967 0.588   12 0.17 0.609 0.5, 2.3 -1.09
CAST/EiJ m 1.05 0.743   12 0.214 0.707 0.4, 2.9 -1.06
NOD/ShiLtJ f 5.15 3.44   10 1.09 0.667 2.0, 11.7 1.56
NOD/ShiLtJ m 3.59 1.65   11 0.498 0.46 2.3, 8.2 0.47
NZO/HlLtJ f 4.56 1.15   10 0.362 0.251 2.7, 6.8 1.19
NZO/HlLtJ m 5.28 1.48   12 0.427 0.28 2.9, 7.6 1.49
PWK/PhJ f 2.99 0.652   10 0.206 0.218 2.0, 4.0 0.2
PWK/PhJ m 5.03 3.08   11 0.929 0.613 2.7, 13.1 1.34
WSB/EiJ f 1.03 0.525   10 0.166 0.51 0.4, 2.1 -1.05
WSB/EiJ m 2.33 4.11   12 1.19 1.76 0.2, 15.2 -0.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.26 0.5726 2.3908 0.1292
129S1/SvImJ m 0.975 0.5227 2.0072 -0.0572
A/J f 2.88 0.5726 4.0108 1.7492
A/J m 2.0333 0.5227 3.0656 1.0011
C57BL/6J f 2.61 0.5726 3.7408 1.4792
C57BL/6J m 2.1583 0.5227 3.1906 1.1261
CAST/EiJ f 0.9667 0.5227 1.9989 -0.0656
CAST/EiJ m 1.05 0.5227 2.0822 0.0178
NOD/ShiLtJ f 5.15 0.5726 6.2808 4.0192
NOD/ShiLtJ m 3.5909 0.5459 4.6691 2.5128
NZO/HlLtJ f 4.56 0.5726 5.6908 3.4292
NZO/HlLtJ m 5.2833 0.5227 6.3156 4.2511
PWK/PhJ f 2.99 0.5726 4.1208 1.8592
PWK/PhJ m 5.0273 0.5459 6.1054 3.9491
WSB/EiJ f 1.03 0.5726 2.1608 -0.1008
WSB/EiJ m 2.3333 0.5227 3.3656 1.3011


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.1175 0.3876 1.883 0.352
A/J both 2.4567 0.3876 3.2222 1.6911
C57BL/6J both 2.3842 0.3876 3.1497 1.6186
CAST/EiJ both 1.0083 0.3696 1.7382 0.2784
NOD/ShiLtJ both 4.3705 0.3956 5.1516 3.5893
NZO/HlLtJ both 4.9217 0.3876 5.6872 4.1561
PWK/PhJ both 4.0086 0.3956 4.7898 3.2274
WSB/EiJ both 1.6817 0.3876 2.4472 0.9161




  GWAS USING LINEAR MIXED MODELS