Project measure / variable:   GMC15   PDW

ID, description, units MPD:56436   PDW   platelet corpuscular distribution width (PDW)   [fL]  
Data set, strains GMC15   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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GMC15 - platelet corpuscular distribution width (PDW)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means5.43   fL 5.41   fL
Median of the strain means5.62   fL 5.32   fL
SD of the strain means± 0.796 ± 0.758
Coefficient of variation (CV)0.147 0.140
Min–max range of strain means4.42   –   6.43   fL 4.57   –   6.77   fL
Mean sample size per strain10.2   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0003 0.0003 0.0012 0.9725
strain 7 88.1627 12.5947 57.5778 < 0.0001
sex:strain 7 5.8982 0.8426 3.852 0.0007
Residuals 160 34.9987 0.2187


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.61 0.191   10 0.0605 0.0415 4.4, 4.9 -1.03
129S1/SvImJ m 4.69 0.235   12 0.0679 0.0502 4.3, 5.0 -0.95
A/J f 5.57 0.514   10 0.163 0.0923 5.2, 6.8 0.18
A/J m 5.27 0.264   12 0.0762 0.0501 5.0, 5.8 -0.18
C57BL/6J f 5.68 0.551   10 0.174 0.0971 5.2, 6.9 0.32
C57BL/6J m 5.38 0.134   12 0.0386 0.0248 5.2, 5.6 -0.04
CAST/EiJ f 4.42 0.154   12 0.0446 0.0349 4.3, 4.8 -1.26
CAST/EiJ m 4.57 0.183   12 0.0527 0.04 4.3, 4.9 -1.11
NOD/ShiLtJ f 6.3 1.25   10 0.396 0.199 5.1, 8.3 1.1
NOD/ShiLtJ m 5.55 0.446   11 0.134 0.0804 5.1, 6.6 0.18
NZO/HlLtJ f 6.43 0.236   10 0.0746 0.0367 6.1, 6.9 1.26
NZO/HlLtJ m 6.77 0.456   12 0.131 0.0672 6.3, 7.8 1.79
PWK/PhJ f 5.83 0.206   10 0.0651 0.0353 5.5, 6.2 0.51
PWK/PhJ m 6.19 0.596   11 0.18 0.0962 5.6, 7.7 1.03
WSB/EiJ f 4.57 0.183   10 0.0578 0.04 4.3, 4.9 -1.08
WSB/EiJ m 4.86 0.623   12 0.18 0.128 4.3, 6.7 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.61 0.1479 4.9021 4.3179
129S1/SvImJ m 4.6917 0.135 4.9583 4.425
A/J f 5.57 0.1479 5.8621 5.2779
A/J m 5.2667 0.135 5.5333 5.0
C57BL/6J f 5.68 0.1479 5.9721 5.3879
C57BL/6J m 5.3833 0.135 5.65 5.1167
CAST/EiJ f 4.425 0.135 4.6916 4.1584
CAST/EiJ m 4.5667 0.135 4.8333 4.3
NOD/ShiLtJ f 6.3 0.1479 6.5921 6.0079
NOD/ShiLtJ m 5.5455 0.141 5.8239 5.267
NZO/HlLtJ f 6.43 0.1479 6.7221 6.1379
NZO/HlLtJ m 6.775 0.135 7.0416 6.5084
PWK/PhJ f 5.83 0.1479 6.1221 5.5379
PWK/PhJ m 6.1909 0.141 6.4694 5.9124
WSB/EiJ f 4.57 0.1479 4.8621 4.2779
WSB/EiJ m 4.8583 0.135 5.125 4.5917


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.6508 0.1001 4.8486 4.4531
A/J both 5.4183 0.1001 5.6161 5.2206
C57BL/6J both 5.5317 0.1001 5.7294 5.3339
CAST/EiJ both 4.4958 0.0955 4.6844 4.3073
NOD/ShiLtJ both 5.9227 0.1022 6.1245 5.7209
NZO/HlLtJ both 6.6025 0.1001 6.8002 6.4048
PWK/PhJ both 6.0105 0.1022 6.2122 5.8087
WSB/EiJ both 4.7142 0.1001 4.9119 4.5164




  GWAS USING LINEAR MIXED MODELS