Project measure / variable:   GMC15   PLT

ID, description, units MPD:56431   PLT   platelet count (PLT; units per volume x 103)   [n/µL]  
Data set, strains GMC15   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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GMC15 - platelet count (PLT; units per volume x 103)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means818   n/µL 955   n/µL
Median of the strain means758   n/µL 1006   n/µL
SD of the strain means± 228 ± 208
Coefficient of variation (CV)0.278 0.218
Min–max range of strain means529   –   1229   n/µL 706   –   1255   n/µL
Mean sample size per strain10.2   mice 11.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 913472.7423 913472.7423 14.062 0.0002
strain 7 5880459.3616 840065.6231 12.932 < 0.0001
sex:strain 7 1412217.6281 201745.3754 3.1057 0.0042
Residuals 161 10458628.9121 64960.428


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 529.0 95.9   10 30.3 0.181 408.0, 707.0 -1.27
129S1/SvImJ m 721.0 81.1   12 23.4 0.112 521.0, 825.0 -1.13
A/J f 968.0 205.0   10 64.9 0.212 747.0, 1409.0 0.66
A/J m 1020.0 110.0   12 31.7 0.108 862.0, 1218.0 0.31
C57BL/6J f 978.0 82.4   10 26.0 0.0843 810.0, 1113.0 0.7
C57BL/6J m 1109.0 238.0   12 68.7 0.215 637.0, 1568.0 0.74
CAST/EiJ f 618.0 94.0   12 27.1 0.152 486.0, 813.0 -0.88
CAST/EiJ m 706.0 80.8   12 23.3 0.115 639.0, 921.0 -1.2
NOD/ShiLtJ f 718.0 384.0   10 121.0 0.534 341.0, 1472.0 -0.44
NOD/ShiLtJ m 1255.0 414.0   12 119.0 0.33 385.0, 2038.0 1.44
NZO/HlLtJ f 1229.0 291.0   10 92.0 0.237 953.0, 1850.0 1.8
NZO/HlLtJ m 1098.0 388.0   12 112.0 0.353 520.0, 1888.0 0.69
PWK/PhJ f 708.0 124.0   10 39.1 0.175 553.0, 923.0 -0.48
PWK/PhJ m 740.0 475.0   11 143.0 0.643 226.0, 1984.0 -1.03
WSB/EiJ f 798.0 114.0   10 36.1 0.143 576.0, 957.0 -0.09
WSB/EiJ m 993.0 269.0   12 77.8 0.271 217.0, 1247.0 0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 529.4 80.598 688.5656 370.2344
129S1/SvImJ m 721.4167 73.5756 866.7144 576.119
A/J f 968.5 80.598 1127.6656 809.3344
A/J m 1020.1667 73.5756 1165.4644 874.869
C57BL/6J f 977.5 80.598 1136.6656 818.3344
C57BL/6J m 1108.5833 73.5756 1253.881 963.2856
CAST/EiJ f 617.9167 73.5756 763.2144 472.619
CAST/EiJ m 705.5833 73.5756 850.881 560.2856
NOD/ShiLtJ f 717.9 80.598 877.0656 558.7344
NOD/ShiLtJ m 1254.9167 73.5756 1400.2144 1109.619
NZO/HlLtJ f 1228.9 80.598 1388.0656 1069.7344
NZO/HlLtJ m 1098.0 73.5756 1243.2977 952.7023
PWK/PhJ f 708.2 80.598 867.3656 549.0344
PWK/PhJ m 739.6364 76.8472 891.3949 587.8779
WSB/EiJ f 797.6 80.598 956.7656 638.4344
WSB/EiJ m 992.9167 73.5756 1138.2144 847.619


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 625.4083 54.5651 733.164 517.6527
A/J both 994.3333 54.5651 1102.089 886.5777
C57BL/6J both 1043.0417 54.5651 1150.7973 935.286
CAST/EiJ both 661.75 52.0258 764.491 559.009
NOD/ShiLtJ both 986.4083 54.5651 1094.164 878.6527
NZO/HlLtJ both 1163.45 54.5651 1271.2057 1055.6943
PWK/PhJ both 723.9182 55.6811 833.8777 613.9587
WSB/EiJ both 895.2583 54.5651 1003.014 787.5027




  GWAS USING LINEAR MIXED MODELS