Project measure / variable:   GMC14   retinal_thickness_R

ID, description, units MPD:56352   retinal_thickness_R   retinal thickness, optical coherence tomography   [µm]  right eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-17wks
Procedure computed tomography
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  STRAIN COMPARISON PLOT
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GMC14 - retinal thickness, optical coherence tomography right eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means230   µm 230   µm
Median of the strain means231   µm 227   µm
SD of the strain means± 11.7 ± 8.08
Coefficient of variation (CV)0.0509 0.0351
Min–max range of strain means211   –   249   µm 219   –   243   µm
Mean sample size per strain12.6   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0699 0.0699 0.0005 0.9825
strain 7 17668.566 2524.0809 17.353 < 0.0001
sex:strain 7 2210.3356 315.7622 2.1709 0.0387
Residuals 184 26763.6484 145.4546


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 237.0 8.89   15 2.29 0.0375 226.0, 260.0 0.58
129S1/SvImJ m 235.0 12.5   16 3.13 0.0534 210.0, 254.0 0.6
A/J f 236.0 9.91   13 2.75 0.042 220.0, 254.0 0.49
A/J m 243.0 10.5   15 2.71 0.0432 229.0, 273.0 1.59
C57BL/6J f 249.0 9.55   15 2.46 0.0383 232.0, 266.0 1.6
C57BL/6J m 239.0 23.8   16 5.95 0.0998 156.0, 257.0 1.1
CAST/EiJ f 229.0 4.11   18 0.968 0.0179 223.0, 236.0 -0.11
CAST/EiJ m 225.0 6.56   14 1.75 0.0291 214.0, 241.0 -0.63
NOD/ShiLtJ f 211.0 17.6   17 4.27 0.0833 155.0, 228.0 -1.64
NOD/ShiLtJ m 219.0 11.7   16 2.92 0.0532 194.0, 248.0 -1.38
NZO/HlLtJ f 229.0 8.58   16 2.15 0.0374 216.0, 246.0 -0.11
NZO/HlLtJ m 226.0 9.02   16 2.26 0.0399 207.0, 240.0 -0.51
PWK/PhJ f 233.0 3.0   3 1.73 0.0129 230.0, 236.0 0.23
PWK/PhJ m 226.0 4.95   2   3.5 0.0219 223.0, 230.0 -0.51
WSB/EiJ f 218.0 13.0   4 6.51 0.0599 198.0, 225.0 -1.05
WSB/EiJ m 228.0 5.16   4 2.58 0.0226 222.0, 234.0 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 237.1333 3.114 243.2771 230.9896
129S1/SvImJ m 235.0 3.0151 240.9486 229.0514
A/J f 236.0 3.345 242.5994 229.4006
A/J m 242.7333 3.114 248.8771 236.5896
C57BL/6J f 249.4667 3.114 255.6104 243.3229
C57BL/6J m 238.5625 3.0151 244.5111 232.6139
CAST/EiJ f 228.8333 2.8427 234.4418 223.2249
CAST/EiJ m 225.0714 3.2233 231.4308 218.7121
NOD/ShiLtJ f 211.3529 2.9251 217.124 205.5819
NOD/ShiLtJ m 219.125 3.0151 225.0736 213.1764
NZO/HlLtJ f 229.25 3.0151 235.1986 223.3014
NZO/HlLtJ m 226.125 3.0151 232.0736 220.1764
PWK/PhJ f 233.0 6.9631 246.7378 219.2622
PWK/PhJ m 226.5 8.528 243.3253 209.6747
WSB/EiJ f 217.5 6.0302 229.3973 205.6027
WSB/EiJ m 228.0 6.0302 239.8973 216.1027


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 236.0667 2.1672 240.3425 231.7908
A/J both 239.3667 2.285 243.8749 234.8584
C57BL/6J both 244.0146 2.1672 248.2904 239.7387
CAST/EiJ both 226.9524 2.1489 231.192 222.7128
NOD/ShiLtJ both 215.239 2.1004 219.383 211.095
NZO/HlLtJ both 227.6875 2.132 231.8938 223.4812
PWK/PhJ both 229.75 5.5048 240.6107 218.8893
WSB/EiJ both 222.75 4.264 231.1626 214.3374




  GWAS USING LINEAR MIXED MODELS