Project measure / variable:   GMC14   fundus_vessels_R

ID, description, units MPD:56342   fundus_vessels_R   number of main vessels in fundus   [n]  right eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-17wks
Procedure computed tomography
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  STRAIN COMPARISON PLOT
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GMC14 - number of main vessels in fundus right eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means10.2   n 10.4   n
Median of the strain means10.6   n 10.6   n
SD of the strain means± 1.54 ± 1.28
Coefficient of variation (CV)0.151 0.123
Min–max range of strain means7.40   –   12.0   n 8.45   –   11.8   n
Mean sample size per strain11.0   mice 11.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5.38 5.38 1.7432 0.1886
strain 7 241.801 34.543 11.1927 < 0.0001
sex:strain 7 7.7145 1.1021 0.3571 0.9257
Residuals 162 499.9641 3.0862


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.8 1.81   14 0.482 0.167 8.0, 14.0 0.38
129S1/SvImJ m 10.4 1.7   14 0.453 0.163 8.0, 15.0 -0.02
A/J f 7.4 1.43   10 0.452 0.193 5.0, 10.0 -1.82
A/J m 8.45 1.63   11 0.493 0.193 6.0, 12.0 -1.54
C57BL/6J f 9.67 1.8   15 0.465 0.186 7.0, 13.0 -0.35
C57BL/6J m 10.1 1.6   15 0.413 0.158 8.0, 13.0 -0.25
CAST/EiJ f 11.3 2.31   12 0.667 0.204 6.0, 15.0 0.7
CAST/EiJ m 11.6 1.39   14 0.372 0.12 9.0, 14.0 0.92
NOD/ShiLtJ f 8.76 1.56   17 0.379 0.178 6.0, 12.0 -0.94
NOD/ShiLtJ m 8.71 2.09   14 0.559 0.24 6.0, 12.0 -1.33
NZO/HlLtJ f 10.3 1.4   16 0.35 0.136 7.0, 12.0 0.05
NZO/HlLtJ m 10.8 2.02   16 0.504 0.188 8.0, 14.0 0.3
PWK/PhJ f 11.5 2.12   2   1.5 0.184 10.0, 13.0 0.83
PWK/PhJ m 11.5 2.12   2   1.5 0.184 10.0, 13.0 0.84
WSB/EiJ f 12.0 1.41   2   1.0 0.118 11.0, 13.0 1.15
WSB/EiJ m 11.8 2.06   4 1.03 0.175 10.0, 14.0 1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.7857 0.4695 11.7129 9.8586
129S1/SvImJ m 10.4286 0.4695 11.3557 9.5014
A/J f 7.4 0.5555 8.497 6.303
A/J m 8.4545 0.5297 9.5005 7.4086
C57BL/6J f 9.6667 0.4536 10.5624 8.7709
C57BL/6J m 10.1333 0.4536 11.0291 9.2376
CAST/EiJ f 11.3333 0.5071 12.3348 10.3319
CAST/EiJ m 11.6429 0.4695 12.57 10.7157
NOD/ShiLtJ f 8.7647 0.4261 9.6061 7.9233
NOD/ShiLtJ m 8.7143 0.4695 9.6414 7.7871
NZO/HlLtJ f 10.3125 0.4392 11.1798 9.4452
NZO/HlLtJ m 10.75 0.4392 11.6173 9.8827
PWK/PhJ f 11.5 1.2422 13.953 9.047
PWK/PhJ m 11.5 1.2422 13.953 9.047
WSB/EiJ f 12.0 1.2422 14.453 9.547
WSB/EiJ m 11.75 0.8784 13.4845 10.0155


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.6071 0.332 11.2627 9.9515
A/J both 7.9273 0.3838 8.6852 7.1694
C57BL/6J both 9.9 0.3207 10.5334 9.2666
CAST/EiJ both 11.4881 0.3456 12.1705 10.8057
NOD/ShiLtJ both 8.7395 0.317 9.3655 8.1135
NZO/HlLtJ both 10.5312 0.3106 11.1445 9.918
PWK/PhJ both 11.5 0.8784 13.2345 9.7655
WSB/EiJ both 11.875 0.7607 13.3772 10.3728




  GWAS USING LINEAR MIXED MODELS