Project measure / variable:   GMC14   fundus_vessels_L

ID, description, units MPD:56341   fundus_vessels_L   number of main vessels in fundus   [n]  left eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-17wks
Procedure computed tomography
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  STRAIN COMPARISON PLOT
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GMC14 - number of main vessels in fundus left eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means10.3   n 10.2   n
Median of the strain means10.4   n 10.6   n
SD of the strain means± 1.37 ± 1.53
Coefficient of variation (CV)0.133 0.150
Min–max range of strain means8.50   –   13.0   n 7.46   –   12.2   n
Mean sample size per strain11.6   mice 12.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.2805 1.2805 0.4836 0.4877
strain 7 251.9046 35.9864 13.5907 < 0.0001
sex:strain 7 34.4125 4.9161 1.8566 0.0794
Residuals 175 463.3762 2.6479


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.4 0.506   13 0.14 0.0488 10.0, 11.0 0.07
129S1/SvImJ m 10.9 2.31   15 0.597 0.212 8.0, 15.0 0.45
A/J f 8.5 1.31   12 0.379 0.155 6.0, 10.0 -1.31
A/J m 7.46 0.967   13 0.268 0.13 5.0, 9.0 -1.79
C57BL/6J f 10.0 1.71   16 0.428 0.171 7.0, 14.0 -0.22
C57BL/6J m 10.2 1.68   16 0.421 0.165 7.0, 13.0 0.0
CAST/EiJ f 10.5 1.98   13 0.55 0.188 6.0, 13.0 0.14
CAST/EiJ m 11.3 1.5   15 0.386 0.132 9.0, 14.0 0.71
NOD/ShiLtJ f 8.82 1.51   17 0.366 0.171 6.0, 11.0 -1.08
NOD/ShiLtJ m 8.88 1.89   16 0.473 0.213 5.0, 12.0 -0.86
NZO/HlLtJ f 10.9 1.53   16 0.382 0.14 8.0, 13.0 0.43
NZO/HlLtJ m 11.2 1.82   17 0.442 0.162 8.0, 15.0 0.65
PWK/PhJ f 13.0 1.0   3 0.577 0.0769 12.0, 14.0 1.96
PWK/PhJ m 9.5 0.707   2   0.5 0.0744 9.0, 10.0 -0.46
WSB/EiJ f 10.3 0.577   3 0.333 0.0559 10.0, 11.0 0.0
WSB/EiJ m 12.2 1.71   4 0.854 0.139 10.0, 14.0 1.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.3846 0.4513 11.2753 9.4939
129S1/SvImJ m 10.9333 0.4201 11.7625 10.1041
A/J f 8.5 0.4697 9.4271 7.5729
A/J m 7.4615 0.4513 8.3523 6.5708
C57BL/6J f 10.0 0.4068 10.8029 9.1971
C57BL/6J m 10.1875 0.4068 10.9904 9.3846
CAST/EiJ f 10.5385 0.4513 11.4292 9.6477
CAST/EiJ m 11.3333 0.4201 12.1625 10.5041
NOD/ShiLtJ f 8.8235 0.3947 9.6024 8.0446
NOD/ShiLtJ m 8.875 0.4068 9.6779 8.0721
NZO/HlLtJ f 10.9375 0.4068 11.7404 10.1346
NZO/HlLtJ m 11.2353 0.3947 12.0142 10.4564
PWK/PhJ f 13.0 0.9395 14.8542 11.1458
PWK/PhJ m 9.5 1.1506 11.7709 7.2291
WSB/EiJ f 10.3333 0.9395 12.1875 8.4792
WSB/EiJ m 12.25 0.8136 13.8558 10.6442


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.659 0.3083 11.2674 10.0505
A/J both 7.9808 0.3257 8.6236 7.338
C57BL/6J both 10.0937 0.2877 10.6615 9.526
CAST/EiJ both 10.9359 0.3083 11.5444 10.3274
NOD/ShiLtJ both 8.8493 0.2834 9.4086 8.29
NZO/HlLtJ both 11.0864 0.2834 11.6457 10.5271
PWK/PhJ both 11.25 0.7427 12.7158 9.7842
WSB/EiJ both 11.2917 0.6214 12.5181 10.0652




  GWAS USING LINEAR MIXED MODELS