Project measure / variable:   GMC14   lens_max_density_R

ID, description, units MPD:56334   lens_max_density_R   maximal density value of lens, Scheimpflug imaging   [%]  right eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-16wks
Procedure Scheimpflug imaging
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  STRAIN COMPARISON PLOT
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GMC14 - maximal density value of lens, Scheimpflug imaging right eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means8.76   % 8.44   %
Median of the strain means8.77   % 8.51   %
SD of the strain means± 1.77 ± 1.83
Coefficient of variation (CV)0.202 0.217
Min–max range of strain means6.38   –   11.0   % 6.10   –   11.1   %
Mean sample size per strain13.8   mice 12.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.0336 1.0336 0.1476 0.7013
strain 7 522.2376 74.6054 10.6516 < 0.0001
sex:strain 7 29.0438 4.1491 0.5924 0.7617
Residuals 195 1365.804 7.0041


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.2 1.65   16 0.412 0.162 7.5, 12.9 0.81
129S1/SvImJ m 9.93 2.75   16 0.689 0.277 6.3, 14.5 0.81
A/J f 11.0 2.88   16 0.719 0.26 7.5, 18.4 1.27
A/J m 11.1 2.53   14 0.677 0.228 8.6, 17.3 1.45
C57BL/6J f 7.11 1.37   16 0.343 0.193 5.5, 9.4 -0.93
C57BL/6J m 7.49 1.7   16 0.425 0.227 5.9, 11.0 -0.52
CAST/EiJ f 8.88 5.14   19 1.18 0.579 4.7, 27.8 0.07
CAST/EiJ m 7.47 4.06   16 1.02 0.544 3.9, 18.0 -0.53
NOD/ShiLtJ f 8.66 0.998   18 0.235 0.115 7.1, 10.2 -0.06
NOD/ShiLtJ m 9.57 1.63   16 0.408 0.17 7.1, 11.8 0.62
NZO/HlLtJ f 6.38 0.839   17 0.204 0.131 5.5, 8.6 -1.35
NZO/HlLtJ m 6.36 0.766   17 0.186 0.12 5.1, 7.8 -1.14
PWK/PhJ f 7.15 0.768   4 0.384 0.107 6.3, 7.8 -0.91
PWK/PhJ m 6.1 0.283   2   0.2 0.0464 5.9, 6.3 -1.28
WSB/EiJ f 10.7 3.75   4 1.88 0.351 7.8, 16.1 1.1
WSB/EiJ m 9.53 5.39   4 2.69 0.566 6.7, 17.6 0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.1688 0.6616 11.4736 8.8639
129S1/SvImJ m 9.9313 0.6616 11.2361 8.6264
A/J f 11.0437 0.6616 12.3486 9.7389
A/J m 11.0929 0.7073 12.4878 9.6979
C57BL/6J f 7.1125 0.6616 8.4174 5.8076
C57BL/6J m 7.4875 0.6616 8.7924 6.1826
CAST/EiJ f 8.8789 0.6072 10.0764 7.6815
CAST/EiJ m 7.4688 0.6616 8.7736 6.1639
NOD/ShiLtJ f 8.6611 0.6238 9.8914 7.4309
NOD/ShiLtJ m 9.5687 0.6616 10.8736 8.2639
NZO/HlLtJ f 6.3824 0.6419 7.6483 5.1164
NZO/HlLtJ m 6.3647 0.6419 7.6306 5.0988
PWK/PhJ f 7.15 1.3233 9.7597 4.5403
PWK/PhJ m 6.1 1.8714 9.7907 2.4093
WSB/EiJ f 10.675 1.3233 13.2847 8.0653
WSB/EiJ m 9.525 1.3233 12.1347 6.9153


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.05 0.4678 10.9727 9.1273
A/J both 11.0683 0.4843 12.0234 10.1132
C57BL/6J both 7.3 0.4678 8.2227 6.3773
CAST/EiJ both 8.1738 0.449 9.0594 7.2883
NOD/ShiLtJ both 9.1149 0.4547 10.0116 8.2182
NZO/HlLtJ both 6.3735 0.4539 7.2687 5.4784
PWK/PhJ both 6.625 1.146 8.8851 4.3649
WSB/EiJ both 10.1 0.9357 11.9454 8.2546




  GWAS USING LINEAR MIXED MODELS