Project measure / variable:   GMC14   lens_max_density_L

ID, description, units MPD:56333   lens_max_density_L   maximal density value of lens, Scheimpflug imaging   [%]  left eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-16wks
Procedure Scheimpflug imaging
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  STRAIN COMPARISON PLOT
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GMC14 - maximal density value of lens, Scheimpflug imaging left eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means9.00   % 8.91   %
Median of the strain means9.18   % 8.55   %
SD of the strain means± 1.65 ± 2.04
Coefficient of variation (CV)0.183 0.229
Min–max range of strain means6.66   –   11.2   % 6.50   –   12.1   %
Mean sample size per strain13.5   mice 12.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6.7295 6.7295 0.5474 0.4603
strain 7 457.5629 65.3661 5.3173 < 0.0001
sex:strain 7 76.4635 10.9234 0.8886 0.5165
Residuals 194 2384.8611 12.2931


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.29 1.74   16 0.435 0.187 7.1, 12.5 0.17
129S1/SvImJ m 10.2 3.14   16 0.785 0.308 6.7, 18.8 0.63
A/J f 11.2 2.09   16 0.522 0.186 8.2, 15.7 1.33
A/J m 11.1 2.06   15 0.533 0.187 8.2, 15.3 1.07
C57BL/6J f 8.05 2.52   16 0.631 0.313 5.5, 15.3 -0.58
C57BL/6J m 7.5 1.32   16 0.33 0.176 5.5, 10.2 -0.69
CAST/EiJ f 11.0 8.66   19 1.99 0.789 5.9, 36.9 1.21
CAST/EiJ m 8.34 5.12   16 1.28 0.613 4.7, 24.3 -0.28
NOD/ShiLtJ f 9.06 1.29   16 0.321 0.142 7.1, 12.5 0.03
NOD/ShiLtJ m 8.76 0.84   16 0.21 0.0959 7.5, 10.6 -0.08
NZO/HlLtJ f 6.66 0.809   17 0.196 0.121 5.5, 8.2 -1.42
NZO/HlLtJ m 6.81 0.703   17 0.171 0.103 5.9, 8.6 -1.03
PWK/PhJ f 7.17 1.39   4 0.697 0.194 5.9, 9.0 -1.11
PWK/PhJ m 6.5 0.283   2   0.2 0.0435 6.3, 6.7 -1.18
WSB/EiJ f 9.6 1.33   4 0.663 0.138 7.8, 11.0 0.36
WSB/EiJ m 12.1 6.79   4 3.4 0.563 6.7, 21.2 1.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.2875 0.8765 11.0163 7.5587
129S1/SvImJ m 10.1938 0.8765 11.9225 8.465
A/J f 11.25 0.8765 12.9788 9.5212
A/J m 11.06 0.9053 12.8455 9.2745
C57BL/6J f 8.05 0.8765 9.7788 6.3212
C57BL/6J m 7.5 0.8765 9.2288 5.7712
CAST/EiJ f 10.9737 0.8044 12.5601 9.3873
CAST/EiJ m 8.3438 0.8765 10.0725 6.615
NOD/ShiLtJ f 9.0563 0.8765 10.785 7.3275
NOD/ShiLtJ m 8.7563 0.8765 10.485 7.0275
NZO/HlLtJ f 6.6647 0.8504 8.3419 4.9876
NZO/HlLtJ m 6.8059 0.8504 8.483 5.1287
PWK/PhJ f 7.175 1.7531 10.6325 3.7175
PWK/PhJ m 6.5 2.4792 11.3897 1.6103
WSB/EiJ f 9.6 1.7531 13.0575 6.1425
WSB/EiJ m 12.075 1.7531 15.5325 8.6175


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.7406 0.6198 10.963 8.5182
A/J both 11.155 0.6301 12.3976 9.9124
C57BL/6J both 7.775 0.6198 8.9974 6.5526
CAST/EiJ both 9.6587 0.5948 10.8319 8.4855
NOD/ShiLtJ both 8.9063 0.6198 10.1287 7.6838
NZO/HlLtJ both 6.7353 0.6013 7.9212 5.5494
PWK/PhJ both 6.8375 1.5182 9.8318 3.8432
WSB/EiJ both 10.8375 1.2396 13.2823 8.3927




  GWAS USING LINEAR MIXED MODELS