Project measure / variable:   GMC14   lens_min_density_L

ID, description, units MPD:56331   lens_min_density_L   minimal density value of lens, Scheimpflug imaging   [%]  left eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-16wks
Procedure Scheimpflug imaging
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC14 - minimal density value of lens, Scheimpflug imaging left eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means5.17   % 5.22   %
Median of the strain means4.58   % 4.58   %
SD of the strain means± 1.36 ± 1.31
Coefficient of variation (CV)0.263 0.250
Min–max range of strain means4.17   –   8.03   % 4.22   –   8.01   %
Mean sample size per strain13.5   mice 12.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0813 0.0813 0.1478 0.701
strain 7 356.3659 50.9094 92.5106 < 0.0001
sex:strain 7 3.9103 0.5586 1.0151 0.4218
Residuals 194 106.76 0.5503


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.17 0.733   16 0.183 0.142 3.5, 5.9 0.0
129S1/SvImJ m 5.65 0.482   16 0.12 0.0853 5.1, 6.7 0.33
A/J f 8.03 1.35   16 0.338 0.168 5.9, 10.2 2.11
A/J m 8.01 1.57   15 0.407 0.197 6.3, 11.0 2.14
C57BL/6J f 4.65 0.635   16 0.159 0.136 3.9, 6.7 -0.38
C57BL/6J m 4.33 0.516   16 0.129 0.119 3.5, 5.1 -0.68
CAST/EiJ f 4.17 0.443   19 0.102 0.106 3.5, 5.1 -0.74
CAST/EiJ m 4.22 0.551   16 0.138 0.13 3.1, 5.5 -0.77
NOD/ShiLtJ f 6.33 0.516   16 0.129 0.0815 5.5, 7.5 0.85
NOD/ShiLtJ m 6.02 0.615   16 0.154 0.102 5.1, 7.1 0.61
NZO/HlLtJ f 4.32 0.331   17 0.0802 0.0765 3.9, 4.7 -0.63
NZO/HlLtJ m 4.46 0.348   17 0.0844 0.078 3.9, 5.1 -0.59
PWK/PhJ f 4.2 0.6   4 0.3 0.143 3.5, 4.7 -0.72
PWK/PhJ m 4.7 0.0   2   0.0 0.0 4.7, 4.7 -0.4
WSB/EiJ f 4.5 0.231   4 0.115 0.0513 4.3, 4.7 -0.49
WSB/EiJ m 4.4 0.383   4 0.191 0.087 3.9, 4.7 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.175 0.1855 5.5408 4.8092
129S1/SvImJ m 5.65 0.1855 6.0158 5.2842
A/J f 8.0312 0.1855 8.397 7.6655
A/J m 8.0067 0.1915 8.3844 7.6289
C57BL/6J f 4.65 0.1855 5.0158 4.2842
C57BL/6J m 4.325 0.1855 4.6908 3.9592
CAST/EiJ f 4.1737 0.1702 4.5093 3.838
CAST/EiJ m 4.225 0.1855 4.5908 3.8592
NOD/ShiLtJ f 6.325 0.1855 6.6908 5.9592
NOD/ShiLtJ m 6.025 0.1855 6.3908 5.6592
NZO/HlLtJ f 4.3235 0.1799 4.6784 3.9687
NZO/HlLtJ m 4.4647 0.1799 4.8196 4.1099
PWK/PhJ f 4.2 0.3709 4.9315 3.4685
PWK/PhJ m 4.7 0.5246 5.7346 3.6654
WSB/EiJ f 4.5 0.3709 5.2315 3.7685
WSB/EiJ m 4.4 0.3709 5.1315 3.6685


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.4125 0.1311 5.6711 5.1539
A/J both 8.019 0.1333 8.2819 7.756
C57BL/6J both 4.4875 0.1311 4.7461 4.2289
CAST/EiJ both 4.1993 0.1259 4.4476 3.9511
NOD/ShiLtJ both 6.175 0.1311 6.4336 5.9164
NZO/HlLtJ both 4.3941 0.1272 4.645 4.1432
PWK/PhJ both 4.45 0.3212 5.0835 3.8165
WSB/EiJ both 4.45 0.2623 4.9673 3.9327




  GWAS USING LINEAR MIXED MODELS