Project measure / variable:   GMC13   pNN50

ID, description, units MPD:56242   pNN50   proportion of number of pairs of successive beat-to-beat intervals that exceed 50 ms (6<ms)   [%]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC13 - proportion of number of pairs of successive beat-to-beat intervals that exceed 50 ms (6<ms)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means4.56   % 5.18   %
Median of the strain means0.656   % 1.34   %
SD of the strain means± 7.70 ± 9.58
Coefficient of variation (CV)1.69 1.85
Min–max range of strain means0   –   19.4   % 0   –   24.5   %
Mean sample size per strain11.3   mice 10.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 28.0155 28.0155 0.124 0.7254
strain 5 3115.5145 623.1029 2.757 0.0215
sex:strain 5 3824.8632 764.9726 3.3847 0.0068
Residuals 120 27121.3986 226.0117


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   12 0.0 0.0 -0.59
129S1/SvImJ m 0.833 2.89   12 0.833 3.46 -0.45
A/J f 19.4 34.0   12 9.82 1.75 1.93
A/J m 0.0 0.0   12 0.0 0.0 -0.54
C57BL/6J f 0.0 0.0   12 0.0 0.0 -0.59
C57BL/6J m 3.89 12.3   12 3.56 3.17 -0.13
NOD/ShiLtJ f 0.834 2.36   8 0.834 2.83 -0.48
NOD/ShiLtJ m 0.0 0.0   8 0.0 0.0 -0.54
NZO/HlLtJ f 6.64 11.5   13 3.2 1.74 0.27
NZO/HlLtJ m 24.5 42.0   7 15.9 1.71 2.02
PWK/PhJ f 0.478 1.59   11 0.478 3.32 -0.53
PWK/PhJ m 1.85 5.77   13 1.6 3.12 -0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 4.3399 8.5926 -8.5926
129S1/SvImJ m 0.8333 4.3399 9.4259 -7.7593
A/J f 19.3975 4.3399 27.9901 10.8049
A/J m 0.0 4.3399 8.5926 -8.5926
C57BL/6J f 0.0 4.3399 8.5926 -8.5926
C57BL/6J m 3.8925 4.3399 12.4851 -4.7001
NOD/ShiLtJ f 0.8338 5.3152 11.3575 -9.69
NOD/ShiLtJ m 0.0 5.3152 10.5237 -10.5237
NZO/HlLtJ f 6.6431 4.1696 14.8986 -1.6124
NZO/HlLtJ m 24.5457 5.6822 35.7961 13.2954
PWK/PhJ f 0.4782 4.5328 9.4529 -8.4965
PWK/PhJ m 1.8508 4.1696 10.1063 -6.4047


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4167 3.0687 6.4926 -5.6592
A/J both 9.6987 3.0687 15.7746 3.6229
C57BL/6J both 1.9463 3.0687 8.0221 -4.1296
NOD/ShiLtJ both 0.4169 3.7584 7.8583 -7.0245
NZO/HlLtJ both 15.5944 3.5239 22.5716 8.6172
PWK/PhJ both 1.1645 3.0794 7.2616 -4.9326




GWAS analysis not available: At least 12 strains are required