Project measure / variable:   GMC13   rMSSD

ID, description, units MPD:56241   rMSSD   root mean square of successive differences of neighboring RR intervals   [rms(ms)]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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GMC13 - root mean square of successive differences of neighboring RR intervals



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means2.79   rms(ms) 3.04   rms(ms)
Median of the strain means1.89   rms(ms) 1.40   rms(ms)
SD of the strain means± 2.77 ± 3.85
Coefficient of variation (CV)0.994 1.27
Min–max range of strain means0.812   –   8.07   rms(ms) 0.644   –   10.7   rms(ms)
Mean sample size per strain11.3   mice 10.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.1395 3.1395 0.0723 0.7885
strain 5 460.5492 92.1098 2.1199 0.0676
sex:strain 5 553.3299 110.666 2.547 0.0315
Residuals 120 5213.9728 43.4498


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.812 0.284   12 0.082 0.35 0.44, 1.35 -0.71
129S1/SvImJ m 0.942 0.636   12 0.184 0.675 0.33, 2.58 -0.54
A/J f 8.07 13.9   12 4.02 1.72 0.91, 46.0 1.9
A/J m 1.17 0.329   12 0.0949 0.281 0.51, 1.71 -0.48
C57BL/6J f 0.958 0.905   12 0.261 0.944 0.31, 3.74 -0.66
C57BL/6J m 1.64 2.5   12 0.722 1.52 0.48, 9.48 -0.36
NOD/ShiLtJ f 0.996 0.738   8 0.261 0.741 0.5, 2.78 -0.65
NOD/ShiLtJ m 0.644 0.223   8 0.0789 0.346 0.43, 1.14 -0.62
NZO/HlLtJ f 3.12 3.58   13 0.993 1.15 0.48, 9.45 0.12
NZO/HlLtJ m 10.7 17.6   7 6.66 1.64 0.58, 43.8 1.99
PWK/PhJ f 2.79 7.18   11 2.16 2.57 0.37, 24.4 0.0
PWK/PhJ m 3.13 6.19   13 1.72 1.98 0.32, 18.9 0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.8117 1.9028 4.5792 -2.9558
129S1/SvImJ m 0.9417 1.9028 4.7092 -2.8258
A/J f 8.0742 1.9028 11.8417 4.3067
A/J m 1.1708 1.9028 4.9383 -2.5967
C57BL/6J f 0.9583 1.9028 4.7258 -2.8092
C57BL/6J m 1.6433 1.9028 5.4108 -2.1242
NOD/ShiLtJ f 0.9962 2.3305 5.6105 -3.618
NOD/ShiLtJ m 0.6438 2.3305 5.258 -3.9705
NZO/HlLtJ f 3.1208 1.8282 6.7405 -0.4989
NZO/HlLtJ m 10.7286 2.4914 15.6614 5.7958
PWK/PhJ f 2.7918 1.9875 6.7268 -1.1432
PWK/PhJ m 3.1308 1.8282 6.7505 -0.4889


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.8767 1.3455 3.5407 -1.7874
A/J both 4.6225 1.3455 7.2865 1.9585
C57BL/6J both 1.3008 1.3455 3.9649 -1.3632
NOD/ShiLtJ both 0.82 1.6479 4.0827 -2.4427
NZO/HlLtJ both 6.9247 1.5451 9.9839 3.8655
PWK/PhJ both 2.9613 1.3502 5.6346 0.288




  GWAS USING LINEAR MIXED MODELS