Project measure / variable:   GMC13   QT_dispersion

ID, description, units MPD:56221   QT_dispersion   QT dispersion, measured as inter-lead variability of QT intervals   [ms]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC13 - QT dispersion, measured as inter-lead variability of QT intervals



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means19.9   ms 19.7   ms
Median of the strain means19.4   ms 20.1   ms
SD of the strain means± 2.13 ± 0.763
Coefficient of variation (CV)0.107 0.0387
Min–max range of strain means17.9   –   23.5   ms 18.7   –   20.4   ms
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.4592 2.4592 0.0345 0.8528
strain 5 268.7048 53.741 0.7543 0.5841
sex:strain 5 126.3181 25.2636 0.3546 0.8788
Residuals 166 11827.4224 71.2495


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.2 6.03   16 1.51 0.284 8.0, 34.0 0.61
129S1/SvImJ m 20.1 6.85   16 1.71 0.341 8.0, 30.0 0.5
A/J f 23.5 8.13   16 2.03 0.346 14.0, 38.5 1.69
A/J m 20.4 9.68   16 2.42 0.474 1.0, 38.0 0.9
C57BL/6J f 19.3 4.41   16 1.1 0.228 12.0, 29.0 -0.28
C57BL/6J m 18.7 7.62   16 1.9 0.407 -1.33
NOD/ShiLtJ f 18.0 7.05   12 2.03 0.391 -0.89
NOD/ShiLtJ m 18.8 6.06   12 1.75 0.323 1.0, 24.0 -1.2
NZO/HlLtJ f 17.9 8.07   17 1.96 0.451 1.0, 30.0 -0.94
NZO/HlLtJ m 20.3 11.0   11 3.31 0.541 9.0, 48.0 0.76
PWK/PhJ f 19.5 12.1   15 3.12 0.62 7.0, 56.5 -0.19
PWK/PhJ m 20.0 11.3   15 2.91 0.563 6.0, 55.5 0.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.1875 2.1102 25.3539 17.0211
129S1/SvImJ m 20.0937 2.1102 24.2601 15.9274
A/J f 23.5 2.1102 27.6664 19.3336
A/J m 20.4375 2.1102 24.6039 16.2711
C57BL/6J f 19.3125 2.1102 23.4789 15.1461
C57BL/6J m 18.7187 2.1102 22.8851 14.5524
NOD/ShiLtJ f 18.0 2.4367 22.8109 13.1891
NOD/ShiLtJ m 18.75 2.4367 23.5609 13.9391
NZO/HlLtJ f 17.9118 2.0472 21.9537 13.8698
NZO/HlLtJ m 20.2727 2.545 25.2975 15.2479
PWK/PhJ f 19.4667 2.1794 23.7697 15.1637
PWK/PhJ m 20.0333 2.1794 24.3363 15.7303


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 20.6406 1.4922 23.5867 17.6946
A/J both 21.9687 1.4922 24.9148 19.0227
C57BL/6J both 19.0156 1.4922 21.9617 16.0696
NOD/ShiLtJ both 18.375 1.723 21.7768 14.9732
NZO/HlLtJ both 19.0922 1.6331 22.3166 15.8679
PWK/PhJ both 19.75 1.5411 22.7927 16.7073




GWAS analysis not available: At least 12 strains are required