Project measure / variable:   GMC13   QT

ID, description, units MPD:56215   QT   duration of QT interval   [ms]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC13 - duration of QT interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means39.5   ms 39.4   ms
Median of the strain means39.6   ms 39.8   ms
SD of the strain means± 1.79 ± 2.73
Coefficient of variation (CV)0.0453 0.0693
Min–max range of strain means37.1   –   42.0   ms 35.0   –   42.5   ms
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.9703 1.9703 0.1334 0.7154
strain 5 640.0257 128.0051 8.6683 < 0.0001
sex:strain 5 131.4313 26.2863 1.7801 0.1196
Residuals 166 2451.3362 14.7671


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 42.0 3.84   16 0.959 0.0913 36.0, 50.0 1.38
129S1/SvImJ m 41.5 3.82   16 0.955 0.0921 34.6, 50.0 0.77
A/J f 40.8 6.74   16 1.69 0.165 32.0, 58.0 0.71
A/J m 40.5 5.24   16 1.31 0.129 33.0, 51.0 0.4
C57BL/6J f 38.0 2.36   16 0.59 0.0621 35.9, 43.0 -0.86
C57BL/6J m 39.1 2.02   16 0.505 0.0516 35.0, 43.0 -0.11
NOD/ShiLtJ f 39.8 3.81   12 1.1 0.0956 36.0, 48.0 0.15
NOD/ShiLtJ m 37.8 3.24   12 0.936 0.0857 33.0, 46.0 -0.59
NZO/HlLtJ f 39.5 3.27   17 0.793 0.0828 34.0, 45.0 -0.02
NZO/HlLtJ m 42.5 3.17   11 0.957 0.0748 37.0, 48.0 1.14
PWK/PhJ f 37.1 2.97   15 0.766 0.0799 31.0, 43.0 -1.36
PWK/PhJ m 35.0 2.73   15 0.704 0.0779 31.0, 40.0 -1.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 42.05 0.9607 43.9468 40.1532
129S1/SvImJ m 41.475 0.9607 43.3718 39.5782
A/J f 40.8062 0.9607 42.703 38.9095
A/J m 40.4937 0.9607 42.3905 38.597
C57BL/6J f 37.9562 0.9607 39.853 36.0595
C57BL/6J m 39.125 0.9607 41.0218 37.2282
NOD/ShiLtJ f 39.8333 1.1093 42.0235 37.6431
NOD/ShiLtJ m 37.8333 1.1093 40.0235 35.6431
NZO/HlLtJ f 39.4647 0.932 41.3048 37.6246
NZO/HlLtJ m 42.4545 1.1586 44.7421 40.167
PWK/PhJ f 37.1067 0.9922 39.0656 35.1477
PWK/PhJ m 34.9733 0.9922 36.9323 33.0144


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 41.7625 0.6793 43.1037 40.4213
A/J both 40.65 0.6793 41.9912 39.3088
C57BL/6J both 38.5406 0.6793 39.8818 37.1994
NOD/ShiLtJ both 38.8333 0.7844 40.382 37.2846
NZO/HlLtJ both 40.9596 0.7435 42.4275 39.4917
PWK/PhJ both 36.04 0.7016 37.4252 34.6548




GWAS analysis not available: At least 12 strains are required