Project measure / variable:   GMC13   PR

ID, description, units MPD:56213   PR   duration of PR interval   [ms]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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GMC13 - duration of PR interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means25.7   ms 25.7   ms
Median of the strain means26.3   ms 26.1   ms
SD of the strain means± 2.27 ± 2.10
Coefficient of variation (CV)0.0883 0.0819
Min–max range of strain means21.6   –   28.1   ms 21.8   –   27.9   ms
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.4908 1.4908 0.1195 0.73
strain 5 604.1784 120.8357 9.6875 < 0.0001
sex:strain 5 95.3674 19.0735 1.5291 0.1834
Residuals 166 2070.576 12.4733


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 28.1 3.79   16 0.948 0.135 23.0, 37.0 1.06
129S1/SvImJ m 25.2 5.05   16 1.26 0.2 19.0, 34.0 -0.23
A/J f 25.0 2.98   16 0.744 0.119 20.0, 30.0 -0.31
A/J m 26.2 2.32   16 0.581 0.0888 23.0, 32.0 0.25
C57BL/6J f 26.8 3.19   16 0.797 0.119 22.0, 34.0 0.49
C57BL/6J m 26.1 3.13   16 0.782 0.12 21.0, 31.0 0.2
NOD/ShiLtJ f 25.8 4.18   12 1.21 0.162 20.0, 33.0 0.04
NOD/ShiLtJ m 26.9 2.35   12 0.679 0.0874 23.0, 31.0 0.58
NZO/HlLtJ f 26.9 3.88   17 0.941 0.144 20.0, 32.0 0.53
NZO/HlLtJ m 27.9 4.28   11 1.29 0.153 20.0, 32.0 1.05
PWK/PhJ f 21.6 2.96   15 0.764 0.137 18.0, 26.0 -1.81
PWK/PhJ m 21.8 3.38   15 0.874 0.155 16.0, 28.0 -1.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 28.0625 0.8829 29.8057 26.3193
129S1/SvImJ m 25.1937 0.8829 26.937 23.4505
A/J f 24.9875 0.8829 26.7307 23.2443
A/J m 26.1625 0.8829 27.9057 24.4193
C57BL/6J f 26.75 0.8829 28.4932 25.0068
C57BL/6J m 26.1187 0.8829 27.862 24.3755
NOD/ShiLtJ f 25.75 1.0195 27.7629 23.7371
NOD/ShiLtJ m 26.9167 1.0195 28.9296 24.9037
NZO/HlLtJ f 26.8824 0.8566 28.5735 25.1912
NZO/HlLtJ m 27.9091 1.0649 30.0115 25.8067
PWK/PhJ f 21.5933 0.9119 23.3937 19.7929
PWK/PhJ m 21.8 0.9119 23.6004 19.9996


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.6281 0.6243 27.8608 25.3955
A/J both 25.575 0.6243 26.8077 24.3423
C57BL/6J both 26.4344 0.6243 27.667 25.2017
NOD/ShiLtJ both 26.3333 0.7209 27.7567 24.91
NZO/HlLtJ both 27.3957 0.6833 28.7448 26.0466
PWK/PhJ both 21.6967 0.6448 22.9697 20.4236




  GWAS USING LINEAR MIXED MODELS