Project measure / variable:   GMC13   PQ

ID, description, units MPD:56212   PQ   duration of PQ interval   [ms]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC13 - duration of PQ interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means19.6   ms 19.7   ms
Median of the strain means20.2   ms 20.4   ms
SD of the strain means± 2.17 ± 2.01
Coefficient of variation (CV)0.111 0.102
Min–max range of strain means15.6   –   21.6   ms 15.8   –   21.1   ms
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2228 0.2228 0.0221 0.882
strain 5 573.2376 114.6475 11.378 < 0.0001
sex:strain 5 77.3223 15.4645 1.5347 0.1816
Residuals 166 1672.6532 10.0762


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.6 2.73   16 0.684 0.126 18.3, 27.7 0.94
129S1/SvImJ m 19.2 4.75   16 1.19 0.248 12.1, 27.1 -0.23
A/J f 18.8 2.22   16 0.556 0.118 15.0, 22.8 -0.35
A/J m 20.4 2.01   16 0.503 0.0985 16.5, 24.7 0.36
C57BL/6J f 20.9 3.22   16 0.805 0.154 16.2, 28.2 0.61
C57BL/6J m 20.5 2.61   16 0.653 0.128 16.8, 25.3 0.41
NOD/ShiLtJ f 19.8 3.43   12 0.989 0.173 15.0, 25.1 0.11
NOD/ShiLtJ m 21.0 2.34   12 0.677 0.112 17.6, 24.5 0.66
NZO/HlLtJ f 20.7 3.5   17 0.849 0.169 14.7, 25.2 0.52
NZO/HlLtJ m 21.1 3.98   11 1.2 0.188 13.6, 25.0 0.71
PWK/PhJ f 15.6 2.98   15 0.769 0.191 12.2, 21.8 -1.83
PWK/PhJ m 15.8 3.4   15 0.877 0.216 10.4, 21.8 -1.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.6187 0.7936 23.1856 20.0519
129S1/SvImJ m 19.1937 0.7936 20.7606 17.6269
A/J f 18.8437 0.7936 20.4106 17.2769
A/J m 20.4062 0.7936 21.9731 18.8394
C57BL/6J f 20.875 0.7936 22.4418 19.3082
C57BL/6J m 20.4625 0.7936 22.0293 18.8957
NOD/ShiLtJ f 19.7917 0.9163 21.6009 17.9825
NOD/ShiLtJ m 20.95 0.9163 22.7592 19.1408
NZO/HlLtJ f 20.6882 0.7699 22.2083 19.1682
NZO/HlLtJ m 21.1091 0.9571 22.9987 19.2195
PWK/PhJ f 15.62 0.8196 17.2382 14.0018
PWK/PhJ m 15.7667 0.8196 17.3849 14.1485


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 20.4062 0.5611 21.5141 19.2984
A/J both 19.625 0.5611 20.7329 18.5171
C57BL/6J both 20.6687 0.5611 21.7766 19.5609
NOD/ShiLtJ both 20.3708 0.648 21.6501 19.0915
NZO/HlLtJ both 20.8987 0.6142 22.1112 19.6861
PWK/PhJ both 15.6933 0.5795 16.8376 14.5491




  GWAS USING LINEAR MIXED MODELS