Project measure / variable:   GMC13   HR_CV

ID, description, units MPD:56203   HR_CV   heart rate coefficient of variation (signal intensity)   [%]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC13 - heart rate coefficient of variation (signal intensity)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means3.51   % 3.08   %
Median of the strain means3.04   % 1.81   %
SD of the strain means± 2.45 ± 3.76
Coefficient of variation (CV)0.699 1.22
Min–max range of strain means0.743   –   8.07   % 0.728   –   10.6   %
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 27.0662 27.0662 0.6367 0.4261
strain 5 686.2852 137.257 3.2287 0.0083
sex:strain 5 608.1204 121.6241 2.861 0.0166
Residuals 166 7056.8989 42.5114


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.743 0.278   16 0.0696 0.375 0.42, 1.28 -1.13
129S1/SvImJ m 0.937 0.679   16 0.17 0.725 0.38, 2.99 -0.57
A/J f 8.07 13.4   16 3.36 1.67 0.8, 41.9 1.86
A/J m 2.31 3.87   16 0.968 1.68 0.6, 16.5 -0.21
C57BL/6J f 2.42 5.47   16 1.37 2.26 0.31, 22.7 -0.44
C57BL/6J m 1.32 1.69   16 0.423 1.29 0.39, 7.2 -0.47
NOD/ShiLtJ f 3.09 5.36   12 1.55 1.73 0.38, 16.7 -0.17
NOD/ShiLtJ m 0.728 0.334   12 0.0963 0.458 0.38, 1.27 -0.63
NZO/HlLtJ f 3.75 6.67   17 1.62 1.78 0.41, 26.7 0.1
NZO/HlLtJ m 10.6 14.5   11 4.39 1.37 0.45, 36.2 2.0
PWK/PhJ f 3.0 4.15   15 1.07 1.38 0.38, 11.8 -0.21
PWK/PhJ m 2.61 4.11   15 1.06 1.57 0.33, 13.8 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.7431 1.63 3.9614 -2.4751
129S1/SvImJ m 0.9369 1.63 4.1551 -2.2814
A/J f 8.0675 1.63 11.2857 4.8493
A/J m 2.3081 1.63 5.5264 -0.9101
C57BL/6J f 2.4225 1.63 5.6407 -0.7957
C57BL/6J m 1.3156 1.63 4.5339 -1.9026
NOD/ShiLtJ f 3.0942 1.8822 6.8103 -0.6219
NOD/ShiLtJ m 0.7283 1.8822 4.4444 -2.9878
NZO/HlLtJ f 3.7541 1.5814 6.8763 0.632
NZO/HlLtJ m 10.5882 1.9659 14.4695 6.7068
PWK/PhJ f 3.0013 1.6835 6.3251 -0.3225
PWK/PhJ m 2.6113 1.6835 5.9351 -0.7125


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.84 1.1526 3.1156 -1.4356
A/J both 5.1878 1.1526 7.4635 2.9122
C57BL/6J both 1.8691 1.1526 4.1447 -0.4066
NOD/ShiLtJ both 1.9113 1.3309 4.5389 -0.7164
NZO/HlLtJ both 7.1711 1.2615 9.6618 4.6805
PWK/PhJ both 2.8063 1.1904 5.1566 0.4561




  GWAS USING LINEAR MIXED MODELS