Project measure / variable:   GMC13   HR_V

ID, description, units MPD:56202   HR_V   heart rate variability, mean of differences between sequential beats; beats per min   [n/min]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC13 - heart rate variability, mean of differences between sequential beats; beats per min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means27.5   n/min 24.3   n/min
Median of the strain means24.5   n/min 13.2   n/min
SD of the strain means± 19.4 ± 30.7
Coefficient of variation (CV)0.708 1.26
Min–max range of strain means5.16   –   63.5   n/min 5.57   –   85.6   n/min
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1587.477 1587.477 0.5624 0.4544
strain 5 42867.3115 8573.4623 3.0372 0.0119
sex:strain 5 41582.1403 8316.4281 2.9461 0.0142
Residuals 166 468592.1101 2822.844


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.16 1.75   16 0.437 0.339 3.0, 8.1 -1.15
129S1/SvImJ m 6.61 5.17   16 1.29 0.782 2.7, 23.0 -0.58
A/J f 63.5 112.0   16 27.9 1.76 6.0, 363.0 1.85
A/J m 16.6 27.6   16 6.91 1.67 4.8, 118.0 -0.25
C57BL/6J f 18.8 44.5   16 11.1 2.37 2.2, 184.0 -0.45
C57BL/6J m 9.79 12.3   16 3.06 1.25 3.1, 52.0 -0.47
NOD/ShiLtJ f 24.6 43.0   12 12.4 1.74 2.7, 132.0 -0.15
NOD/ShiLtJ m 5.57 2.54   12 0.733 0.456 2.9, 9.5 -0.61
NZO/HlLtJ f 28.3 49.8   17 12.1 1.76 3.0, 198.0 0.04
NZO/HlLtJ m 85.6 121.0   11 36.4 1.41 3.2, 288.0 2.0
PWK/PhJ f 24.4 33.6   15 8.66 1.38 3.3, 97.6 -0.16
PWK/PhJ m 21.7 33.6   15 8.68 1.55 2.8, 113.0 -0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.1563 13.2826 31.3809 -21.0684
129S1/SvImJ m 6.6063 13.2826 32.8309 -19.6184
A/J f 63.45 13.2826 89.6746 37.2254
A/J m 16.575 13.2826 42.7996 -9.6496
C57BL/6J f 18.7688 13.2826 44.9934 -7.4559
C57BL/6J m 9.7937 13.2826 36.0184 -16.4309
NOD/ShiLtJ f 24.6333 15.3374 54.9149 -5.6483
NOD/ShiLtJ m 5.5667 15.3374 35.8483 -24.7149
NZO/HlLtJ f 28.2882 12.886 53.7299 2.8466
NZO/HlLtJ m 85.5545 16.0194 117.1826 53.9265
PWK/PhJ f 24.3667 13.7182 51.4513 -2.718
PWK/PhJ m 21.66 13.7182 48.7447 -5.4247


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.8813 9.3922 24.4249 -12.6624
A/J both 40.0125 9.3922 58.5561 21.4689
C57BL/6J both 14.2813 9.3922 32.8249 -4.2624
NOD/ShiLtJ both 15.1 10.8452 36.5123 -6.3123
NZO/HlLtJ both 56.9214 10.2795 77.2168 36.626
PWK/PhJ both 23.0133 9.7002 42.1651 3.8616




GWAS analysis not available: At least 12 strains are required