Project measure / variable:   GMC12   LVPW_diastole

ID, description, units MPD:56135   LVPW_diastole   left ventricular posterior wall width   [mm]  diastole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - left ventricular posterior wall width diastole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.546   mm 0.543   mm
Median of the strain means0.538   mm 0.543   mm
SD of the strain means± 0.0271 ± 0.0242
Coefficient of variation (CV)0.0497 0.0446
Min–max range of strain means0.522   –   0.610   mm 0.511   –   0.576   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0007 0.0007 0.1532 0.6959
strain 7 0.1221 0.0174 3.8214 0.0006
sex:strain 7 0.0344 0.0049 1.0757 0.3794
Residuals 252 1.1499 0.0046


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.541 0.0645   16 0.0161 0.119 0.42, 0.66 -0.19
129S1/SvImJ m 0.576 0.0734   16 0.0183 0.127 0.44, 0.7 1.34
A/J f 0.551 0.0518   15 0.0134 0.094 0.43, 0.62 0.17
A/J m 0.532 0.062   16 0.0155 0.116 0.41, 0.64 -0.47
C57BL/6J f 0.534 0.0689   16 0.0172 0.129 0.41, 0.67 -0.45
C57BL/6J m 0.558 0.0533   16 0.0133 0.0955 0.46, 0.64 0.6
CAST/EiJ f 0.534 0.0628   19 0.0144 0.118 0.42, 0.64 -0.45
CAST/EiJ m 0.539 0.0751   14 0.0201 0.139 0.44, 0.66 -0.19
NOD/ShiLtJ f 0.544 0.0509   18 0.012 0.0935 0.43, 0.65 -0.08
NOD/ShiLtJ m 0.547 0.04   16 0.00999 0.0731 0.5, 0.62 0.14
NZO/HlLtJ f 0.61 0.0769   17 0.0186 0.126 0.48, 0.75 2.35
NZO/HlLtJ m 0.571 0.0728   17 0.0176 0.128 0.43, 0.68 1.13
PWK/PhJ f 0.534 0.0955   19 0.0219 0.179 0.4, 0.72 -0.45
PWK/PhJ m 0.514 0.0792   20 0.0177 0.154 0.39, 0.64 -1.22
WSB/EiJ f 0.522 0.0673   17 0.0163 0.129 0.47, 0.73 -0.89
WSB/EiJ m 0.511 0.0578   16 0.0145 0.113 0.44, 0.62 -1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5412 0.0169 0.5745 0.508
129S1/SvImJ m 0.5756 0.0169 0.6089 0.5424
A/J f 0.5513 0.0174 0.5857 0.517
A/J m 0.5325 0.0169 0.5658 0.4992
C57BL/6J f 0.5344 0.0169 0.5676 0.5011
C57BL/6J m 0.5581 0.0169 0.5914 0.5249
CAST/EiJ f 0.5337 0.0155 0.5642 0.5032
CAST/EiJ m 0.5393 0.0181 0.5748 0.5037
NOD/ShiLtJ f 0.5444 0.0159 0.5758 0.5131
NOD/ShiLtJ m 0.5469 0.0169 0.5801 0.5136
NZO/HlLtJ f 0.61 0.0164 0.6423 0.5777
NZO/HlLtJ m 0.5706 0.0164 0.6029 0.5383
PWK/PhJ f 0.5342 0.0155 0.5647 0.5037
PWK/PhJ m 0.514 0.0151 0.5437 0.4843
WSB/EiJ f 0.5224 0.0164 0.5546 0.4901
WSB/EiJ m 0.5112 0.0169 0.5445 0.478


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.5584 0.0119 0.582 0.5349
A/J both 0.5419 0.0121 0.5658 0.518
C57BL/6J both 0.5462 0.0119 0.5698 0.5227
CAST/EiJ both 0.5365 0.0119 0.5599 0.5131
NOD/ShiLtJ both 0.5457 0.0116 0.5685 0.5228
NZO/HlLtJ both 0.5903 0.0116 0.6131 0.5675
PWK/PhJ both 0.5241 0.0108 0.5454 0.5028
WSB/EiJ both 0.5168 0.0118 0.54 0.4936




  GWAS USING LINEAR MIXED MODELS