Project measure / variable:   GMC12   LVID_systole

ID, description, units MPD:56134   LVID_systole   left ventricular internal dimension   [mm]  systole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - left ventricular internal dimension systole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.932   mm 1.01   mm
Median of the strain means0.820   mm 0.878   mm
SD of the strain means± 0.459 ± 0.435
Coefficient of variation (CV)0.493 0.431
Min–max range of strain means0.580   –   2.00   mm 0.542   –   1.90   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5454 0.5454 3.2887 0.0709
strain 7 49.8476 7.1211 42.9358 < 0.0001
sex:strain 7 1.4888 0.2127 1.2824 0.2594
Residuals 252 41.7953 0.1659


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.646 0.323   16 0.0807 0.5 0.17, 1.23 -0.62
129S1/SvImJ m 0.696 0.382   16 0.0954 0.548 0.26, 1.76 -0.72
A/J f 0.58 0.19   15 0.0492 0.328 0.33, 1.11 -0.77
A/J m 0.735 0.381   16 0.0954 0.519 0.42, 1.98 -0.63
C57BL/6J f 0.991 0.383   16 0.0956 0.386 0.47, 2.01 0.13
C57BL/6J m 1.2 0.519   16 0.13 0.432 0.62, 2.7 0.44
CAST/EiJ f 0.755 0.357   19 0.082 0.473 0.28, 1.74 -0.39
CAST/EiJ m 0.798 0.296   14 0.079 0.371 0.31, 1.26 -0.49
NOD/ShiLtJ f 0.973 0.253   18 0.0596 0.26 0.51, 1.4 0.09
NOD/ShiLtJ m 0.958 0.271   16 0.0678 0.283 0.54, 1.52 -0.12
NZO/HlLtJ f 0.885 0.274   17 0.0665 0.31 0.54, 1.53 -0.1
NZO/HlLtJ m 1.25 0.418   17 0.101 0.335 0.46, 1.94 0.55
PWK/PhJ f 2.0 0.56   19 0.129 0.28 1.09, 2.86 2.32
PWK/PhJ m 1.9 0.765   20 0.171 0.402 0.43, 3.34 2.04
WSB/EiJ f 0.629 0.354   17 0.0858 0.563 0.2, 1.32 -0.66
WSB/EiJ m 0.542 0.221   16 0.0553 0.409 0.25, 0.92 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6456 0.1018 0.8461 0.4451
129S1/SvImJ m 0.6962 0.1018 0.8968 0.4957
A/J f 0.58 0.1052 0.7871 0.3729
A/J m 0.735 0.1018 0.9355 0.5345
C57BL/6J f 0.9906 0.1018 1.1911 0.7901
C57BL/6J m 1.2012 0.1018 1.4018 1.0007
CAST/EiJ f 0.7547 0.0934 0.9387 0.5707
CAST/EiJ m 0.7979 0.1088 1.0122 0.5835
NOD/ShiLtJ f 0.9728 0.096 1.1618 0.7837
NOD/ShiLtJ m 0.9575 0.1018 1.158 0.757
NZO/HlLtJ f 0.8847 0.0988 1.0792 0.6902
NZO/HlLtJ m 1.2482 0.0988 1.4428 1.0537
PWK/PhJ f 1.9989 0.0934 2.183 1.8149
PWK/PhJ m 1.9025 0.0911 2.0818 1.7232
WSB/EiJ f 0.6288 0.0988 0.8233 0.4343
WSB/EiJ m 0.5419 0.1018 0.7424 0.3414


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6709 0.072 0.8127 0.5292
A/J both 0.6575 0.0732 0.8016 0.5134
C57BL/6J both 1.0959 0.072 1.2377 0.9542
CAST/EiJ both 0.7763 0.0717 0.9175 0.635
NOD/ShiLtJ both 0.9651 0.07 1.1029 0.8273
NZO/HlLtJ both 1.0665 0.0698 1.204 0.9289
PWK/PhJ both 1.9507 0.0652 2.0792 1.8223
WSB/EiJ both 0.5853 0.0709 0.725 0.4457




  GWAS USING LINEAR MIXED MODELS