Project measure / variable:   GMC12   LVID_diastole

ID, description, units MPD:56133   LVID_diastole   left ventricular internal dimension   [mm]  diastole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
Procedure echocardiography
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC12 - left ventricular internal dimension diastole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.35   mm 2.53   mm
Median of the strain means2.16   mm 2.35   mm
SD of the strain means± 0.474 ± 0.526
Coefficient of variation (CV)0.201 0.208
Min–max range of strain means1.91   –   3.17   mm 1.95   –   3.30   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.4599 2.4599 15.137 0.0001
strain 7 59.727 8.5324 52.5046 < 0.0001
sex:strain 7 1.1175 0.1596 0.9824 0.4445
Residuals 252 40.9521 0.1625


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.99 0.356   16 0.0891 0.179 1.48, 2.61 -0.77
129S1/SvImJ m 2.11 0.438   16 0.109 0.208 1.68, 3.34 -0.79
A/J f 1.91 0.324   15 0.0836 0.169 1.39, 2.37 -0.94
A/J m 2.17 0.467   16 0.117 0.215 1.28, 3.2 -0.68
C57BL/6J f 2.59 0.409   16 0.102 0.158 1.95, 3.49 0.5
C57BL/6J m 2.7 0.616   16 0.154 0.228 1.95, 4.43 0.33
CAST/EiJ f 1.99 0.378   19 0.0867 0.19 1.4, 3.1 -0.77
CAST/EiJ m 2.18 0.309   14 0.0825 0.142 1.68, 2.65 -0.66
NOD/ShiLtJ f 2.33 0.284   18 0.067 0.122 1.83, 2.93 -0.05
NOD/ShiLtJ m 2.53 0.283   16 0.0708 0.112 2.0, 3.18 0.01
NZO/HlLtJ f 2.86 0.234   17 0.0567 0.0817 2.53, 3.55 1.07
NZO/HlLtJ m 3.3 0.408   17 0.099 0.124 2.44, 4.07 1.47
PWK/PhJ f 3.17 0.505   19 0.116 0.159 2.52, 3.83 1.72
PWK/PhJ m 3.27 0.502   20 0.112 0.153 2.38, 4.26 1.41
WSB/EiJ f 1.99 0.401   17 0.0972 0.202 1.38, 2.72 -0.77
WSB/EiJ m 1.95 0.301   16 0.0754 0.154 1.46, 2.36 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.9913 0.1008 2.1897 1.7928
129S1/SvImJ m 2.1075 0.1008 2.306 1.909
A/J f 1.9127 0.1041 2.1177 1.7077
A/J m 2.1725 0.1008 2.371 1.974
C57BL/6J f 2.5888 0.1008 2.7872 2.3903
C57BL/6J m 2.6988 0.1008 2.8972 2.5003
CAST/EiJ f 1.9916 0.0925 2.1737 1.8094
CAST/EiJ m 2.1757 0.1077 2.3879 1.9635
NOD/ShiLtJ f 2.3333 0.095 2.5205 2.1462
NOD/ShiLtJ m 2.5306 0.1008 2.7291 2.3321
NZO/HlLtJ f 2.8612 0.0978 3.0537 2.6686
NZO/HlLtJ m 3.2976 0.0978 3.4902 3.1051
PWK/PhJ f 3.1658 0.0925 3.3479 2.9837
PWK/PhJ m 3.2695 0.0901 3.447 3.092
WSB/EiJ f 1.9882 0.0978 2.1808 1.7957
WSB/EiJ m 1.9525 0.1008 2.151 1.754


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.0494 0.0713 2.1897 1.909
A/J both 2.0426 0.0724 2.1852 1.8999
C57BL/6J both 2.6437 0.0713 2.7841 2.5034
CAST/EiJ both 2.0836 0.071 2.2235 1.9438
NOD/ShiLtJ both 2.432 0.0693 2.5684 2.2956
NZO/HlLtJ both 3.0794 0.0691 3.2156 2.9433
PWK/PhJ both 3.2176 0.0646 3.3448 3.0905
WSB/EiJ both 1.9704 0.0702 2.1086 1.8321




GWAS analysis not available: At least 12 strains are required