Project measure / variable:   GMC12   IVS_systole

ID, description, units MPD:56132   IVS_systole   interventricular septum   [mm]  systole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - interventricular septum systole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.489   mm 0.503   mm
Median of the strain means0.483   mm 0.495   mm
SD of the strain means± 0.0335 ± 0.0364
Coefficient of variation (CV)0.0684 0.0723
Min–max range of strain means0.442   –   0.553   mm 0.464   –   0.579   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0123 0.0123 4.5297 0.0343
strain 7 0.2483 0.0355 13.0813 < 0.0001
sex:strain 7 0.0429 0.0061 2.2603 0.0301
Residuals 252 0.6834 0.0027


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.469 0.0556   16 0.0139 0.119 0.35, 0.6 -0.61
129S1/SvImJ m 0.524 0.0516   16 0.0129 0.0986 0.4, 0.61 0.58
A/J f 0.485 0.0304   15 0.00786 0.0627 0.42, 0.53 -0.13
A/J m 0.487 0.0405   16 0.0101 0.0831 0.41, 0.55 -0.44
C57BL/6J f 0.519 0.0533   16 0.0133 0.103 0.42, 0.6 0.89
C57BL/6J m 0.482 0.0443   16 0.0111 0.0919 0.4, 0.57 -0.58
CAST/EiJ f 0.489 0.0489   19 0.0112 0.1 0.41, 0.58 -0.01
CAST/EiJ m 0.51 0.0451   14 0.012 0.0884 0.45, 0.59 0.19
NOD/ShiLtJ f 0.476 0.0279   18 0.00658 0.0587 0.43, 0.52 -0.4
NOD/ShiLtJ m 0.503 0.028   16 0.007 0.0556 0.45, 0.56 0.0
NZO/HlLtJ f 0.553 0.0572   17 0.0139 0.103 0.46, 0.66 1.9
NZO/HlLtJ m 0.579 0.059   17 0.0143 0.102 0.41, 0.66 2.09
PWK/PhJ f 0.482 0.0845   19 0.0194 0.175 0.34, 0.63 -0.22
PWK/PhJ m 0.475 0.0668   20 0.0149 0.141 0.38, 0.61 -0.77
WSB/EiJ f 0.442 0.054   17 0.0131 0.122 0.37, 0.6 -1.42
WSB/EiJ m 0.464 0.0408   16 0.0102 0.088 0.39, 0.55 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4688 0.013 0.4944 0.4431
129S1/SvImJ m 0.5238 0.013 0.5494 0.4981
A/J f 0.4853 0.0134 0.5118 0.4589
A/J m 0.4869 0.013 0.5125 0.4612
C57BL/6J f 0.5188 0.013 0.5444 0.4931
C57BL/6J m 0.4825 0.013 0.5081 0.4569
CAST/EiJ f 0.4895 0.0119 0.513 0.4659
CAST/EiJ m 0.51 0.0139 0.5374 0.4826
NOD/ShiLtJ f 0.4756 0.0123 0.4997 0.4514
NOD/ShiLtJ m 0.5031 0.013 0.5288 0.4775
NZO/HlLtJ f 0.5529 0.0126 0.5778 0.5281
NZO/HlLtJ m 0.5794 0.0126 0.6043 0.5545
PWK/PhJ f 0.4816 0.0119 0.5051 0.458
PWK/PhJ m 0.4745 0.0116 0.4974 0.4516
WSB/EiJ f 0.4418 0.0126 0.4666 0.4169
WSB/EiJ m 0.4638 0.013 0.4894 0.4381


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4963 0.0092 0.5144 0.4781
A/J both 0.4861 0.0094 0.5045 0.4677
C57BL/6J both 0.5006 0.0092 0.5188 0.4825
CAST/EiJ both 0.4997 0.0092 0.5178 0.4817
NOD/ShiLtJ both 0.4893 0.0089 0.507 0.4717
NZO/HlLtJ both 0.5662 0.0089 0.5838 0.5486
PWK/PhJ both 0.478 0.0083 0.4945 0.4616
WSB/EiJ both 0.4528 0.0091 0.4706 0.4349




  GWAS USING LINEAR MIXED MODELS