Project measure / variable:   GMC12   IVS_diastole

ID, description, units MPD:56131   IVS_diastole   interventricular septum   [mm]  diastole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
Procedure echocardiography
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC12 - interventricular septum diastole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.495   mm 0.498   mm
Median of the strain means0.486   mm 0.492   mm
SD of the strain means± 0.0313 ± 0.0313
Coefficient of variation (CV)0.0632 0.0629
Min–max range of strain means0.469   –   0.564   mm 0.449   –   0.545   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0003 0.0003 0.1102 0.7401
strain 7 0.2238 0.032 10.2889 < 0.0001
sex:strain 7 0.015 0.0021 0.6884 0.6819
Residuals 252 0.783 0.0031


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.509 0.0541   16 0.0135 0.106 0.45, 0.61 0.45
129S1/SvImJ m 0.537 0.059   16 0.0147 0.11 0.45, 0.64 1.26
A/J f 0.498 0.0474   15 0.0122 0.0952 0.41, 0.59 0.1
A/J m 0.503 0.0482   16 0.0121 0.096 0.41, 0.58 0.17
C57BL/6J f 0.479 0.0658   16 0.0164 0.137 0.37, 0.65 -0.51
C57BL/6J m 0.488 0.0412   16 0.0103 0.0844 0.42, 0.58 -0.31
CAST/EiJ f 0.476 0.0481   19 0.011 0.101 0.39, 0.57 -0.6
CAST/EiJ m 0.485 0.0554   14 0.0148 0.114 0.41, 0.6 -0.4
NOD/ShiLtJ f 0.493 0.0484   18 0.0114 0.0981 0.41, 0.63 -0.06
NOD/ShiLtJ m 0.497 0.0208   16 0.0052 0.0418 0.46, 0.53 -0.02
NZO/HlLtJ f 0.564 0.0681   17 0.0165 0.121 0.46, 0.68 2.21
NZO/HlLtJ m 0.545 0.0579   17 0.014 0.106 0.45, 0.63 1.51
PWK/PhJ f 0.469 0.081   19 0.0186 0.173 0.34, 0.63 -0.83
PWK/PhJ m 0.449 0.0555   20 0.0124 0.124 0.36, 0.55 -1.55
WSB/EiJ f 0.471 0.0588   17 0.0143 0.125 0.37, 0.63 -0.76
WSB/EiJ m 0.477 0.0532   16 0.0133 0.111 0.33, 0.55 -0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5094 0.0139 0.5368 0.4819
129S1/SvImJ m 0.5369 0.0139 0.5643 0.5094
A/J f 0.498 0.0144 0.5263 0.4697
A/J m 0.5025 0.0139 0.5299 0.4751
C57BL/6J f 0.4794 0.0139 0.5068 0.4519
C57BL/6J m 0.4881 0.0139 0.5156 0.4607
CAST/EiJ f 0.4763 0.0128 0.5015 0.4511
CAST/EiJ m 0.485 0.0149 0.5143 0.4557
NOD/ShiLtJ f 0.4933 0.0131 0.5192 0.4675
NOD/ShiLtJ m 0.4975 0.0139 0.5249 0.4701
NZO/HlLtJ f 0.5641 0.0135 0.5907 0.5375
NZO/HlLtJ m 0.5447 0.0135 0.5713 0.5181
PWK/PhJ f 0.4689 0.0128 0.4941 0.4438
PWK/PhJ m 0.4485 0.0125 0.473 0.424
WSB/EiJ f 0.4712 0.0135 0.4978 0.4446
WSB/EiJ m 0.4775 0.0139 0.5049 0.4501


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.5231 0.0099 0.5425 0.5037
A/J both 0.5002 0.01 0.52 0.4805
C57BL/6J both 0.4838 0.0099 0.5032 0.4643
CAST/EiJ both 0.4807 0.0098 0.5 0.4613
NOD/ShiLtJ both 0.4954 0.0096 0.5143 0.4766
NZO/HlLtJ both 0.5544 0.0096 0.5732 0.5356
PWK/PhJ both 0.4587 0.0089 0.4763 0.4411
WSB/EiJ both 0.4743 0.0097 0.4935 0.4552




GWAS analysis not available: At least 12 strains are required