Project measure / variable:   GMC12   EJ_fraction

ID, description, units MPD:56123   EJ_fraction   ejection fraction   [%]  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - ejection fraction



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means90.9   % 91.1   %
Median of the strain means93.9   % 93.6   %
SD of the strain means± 9.11 ± 6.99
Coefficient of variation (CV)0.100 0.0767
Min–max range of strain means68.8   –   96.9   % 74.8   –   96.9   %
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.9886 0.9886 0.0217 0.883
strain 7 16708.4915 2386.9274 52.421 < 0.0001
sex:strain 7 513.9381 73.4197 1.6124 0.1322
Residuals 252 11474.5282 45.5338


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 95.2 5.18   16 1.29 0.0543 80.7, 99.9 0.48
129S1/SvImJ m 94.6 4.73   16 1.18 0.05 82.8, 99.8 0.5
A/J f 96.9 2.61   15 0.675 0.027 89.8, 99.8 0.66
A/J m 94.6 5.41   16 1.35 0.0572 78.8, 98.8 0.5
C57BL/6J f 91.1 6.67   16 1.67 0.0733 76.0, 99.0 0.03
C57BL/6J m 89.0 8.23   16 2.06 0.0925 65.7, 96.5 -0.3
CAST/EiJ f 93.5 4.06   19 0.931 0.0434 86.1, 99.3 0.29
CAST/EiJ m 94.1 5.26   14 1.4 0.0558 81.4, 99.6 0.43
NOD/ShiLtJ f 91.9 4.86   18 1.14 0.0528 81.2, 98.5 0.11
NOD/ShiLtJ m 93.1 3.78   16 0.945 0.0406 86.0, 97.7 0.28
NZO/HlLtJ f 94.3 4.08   17 0.989 0.0432 82.7, 99.4 0.38
NZO/HlLtJ m 91.8 4.28   17 1.04 0.0466 85.3, 99.2 0.1
PWK/PhJ f 68.8 11.4   19 2.61 0.165 45.9, 93.8 -2.42
PWK/PhJ m 74.8 13.8   20 3.1 0.185 42.5, 99.0 -2.33
WSB/EiJ f 95.2 6.34   17 1.54 0.0666 77.2, 99.9 0.48
WSB/EiJ m 96.9 2.25   16 0.562 0.0232 92.8, 99.8 0.83


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 95.2462 1.687 98.5686 91.9239
129S1/SvImJ m 94.6425 1.687 97.9649 91.3201
A/J f 96.8813 1.7423 100.3126 93.45
A/J m 94.6119 1.687 97.9342 91.2895
C57BL/6J f 91.1094 1.687 94.4317 87.787
C57BL/6J m 89.0312 1.687 92.3536 85.7089
CAST/EiJ f 93.5242 1.5481 96.573 90.4754
CAST/EiJ m 94.1314 1.8034 97.6832 90.5797
NOD/ShiLtJ f 91.9133 1.5905 95.0457 88.781
NOD/ShiLtJ m 93.1281 1.687 96.4505 89.8058
NZO/HlLtJ f 94.2741 1.6366 97.4973 91.051
NZO/HlLtJ m 91.7647 1.6366 94.9879 88.5415
PWK/PhJ f 68.7826 1.5481 71.8314 65.7338
PWK/PhJ m 74.82 1.5089 77.7916 71.8484
WSB/EiJ f 95.1512 1.6366 98.3743 91.928
WSB/EiJ m 96.8556 1.687 100.178 93.5333


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 94.9444 1.1929 97.2936 92.5951
A/J both 95.7466 1.2126 98.1347 93.3585
C57BL/6J both 90.0703 1.1929 92.4196 87.7211
CAST/EiJ both 93.8278 1.1884 96.1682 91.4874
NOD/ShiLtJ both 92.5207 1.1593 94.8038 90.2377
NZO/HlLtJ both 93.0194 1.1573 95.2985 90.7403
PWK/PhJ both 71.8013 1.0809 73.93 69.6726
WSB/EiJ both 96.0034 1.1752 98.3179 93.6889




  GWAS USING LINEAR MIXED MODELS