Project measure / variable:   GMC12   fract_shortening

ID, description, units MPD:56122   fract_shortening   fractional shortening   [%]  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - fractional shortening



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means65.0   % 64.6   %
Median of the strain means67.5   % 67.1   %
SD of the strain means± 11.6 ± 9.03
Coefficient of variation (CV)0.178 0.140
Min–max range of strain means38.4   –   74.4   % 45.2   –   74.6   %
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13.5137 13.5137 0.1257 0.7232
strain 7 26493.7192 3784.817 35.2013 < 0.0001
sex:strain 7 1121.0613 160.1516 1.4895 0.1713
Residuals 252 27094.8489 107.5192


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 72.7 13.4   16 3.34 0.184 47.0, 92.7 0.66
129S1/SvImJ m 69.8 10.8   16 2.7 0.154 50.3, 89.4 0.57
A/J f 74.4 8.12   15 2.1 0.109 58.5, 89.2 0.81
A/J m 69.5 10.1   16 2.52 0.145 46.3, 80.8 0.54
C57BL/6J f 63.2 10.9   16 2.73 0.173 43.9, 82.1 -0.16
C57BL/6J m 59.5 9.79   16 2.45 0.165 35.9, 72.0 -0.57
CAST/EiJ f 66.0 8.42   19 1.93 0.128 52.4, 83.3 0.09
CAST/EiJ m 68.7 11.0   14 2.95 0.161 48.4, 87.2 0.45
NOD/ShiLtJ f 63.5 8.48   18 2.0 0.134 47.5, 81.3 -0.13
NOD/ShiLtJ m 65.5 7.05   16 1.76 0.108 53.8, 75.7 0.1
NZO/HlLtJ f 68.9 8.61   17 2.09 0.125 49.8, 85.0 0.34
NZO/HlLtJ m 64.2 8.82   17 2.14 0.137 54.5, 84.1 -0.05
PWK/PhJ f 38.4 9.75   19 2.24 0.254 22.3, 66.0 -2.3
PWK/PhJ m 45.2 14.9   20 3.32 0.328 20.7, 82.1 -2.15
WSB/EiJ f 72.9 13.1   17 3.19 0.18 43.4, 90.7 0.68
WSB/EiJ m 74.6 8.45   16 2.11 0.113 63.1, 89.2 1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 72.7487 2.5923 77.8541 67.6434
129S1/SvImJ m 69.8362 2.5923 74.9416 64.7309
A/J f 74.3833 2.6773 79.6561 69.1106
A/J m 69.4869 2.5923 74.5922 64.3816
C57BL/6J f 63.1887 2.5923 68.2941 58.0834
C57BL/6J m 59.485 2.5923 64.5903 54.3797
CAST/EiJ f 65.9821 2.3788 70.6671 61.2972
CAST/EiJ m 68.7207 2.7713 74.1785 63.2629
NOD/ShiLtJ f 63.4861 2.444 68.2994 58.6728
NOD/ShiLtJ m 65.5306 2.5923 70.6359 60.4253
NZO/HlLtJ f 68.9012 2.5149 73.8541 63.9483
NZO/HlLtJ m 64.2359 2.5149 69.1888 59.283
PWK/PhJ f 38.4174 2.3788 43.1023 33.7324
PWK/PhJ m 45.247 2.3186 49.8133 40.6807
WSB/EiJ f 72.8694 2.5149 77.8223 67.9165
WSB/EiJ m 74.5806 2.5923 79.6859 69.4753


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 71.2925 1.833 74.9025 67.6825
A/J both 71.9351 1.8633 75.6048 68.2654
C57BL/6J both 61.3369 1.833 64.9469 57.7269
CAST/EiJ both 67.3514 1.8261 70.9478 63.755
NOD/ShiLtJ both 64.5084 1.7814 68.0167 61.0001
NZO/HlLtJ both 66.5685 1.7783 70.0707 63.0663
PWK/PhJ both 41.8322 1.6609 45.1033 38.5611
WSB/EiJ both 73.725 1.8059 77.2815 70.1685




  GWAS USING LINEAR MIXED MODELS