Project measure / variable:   Reed2   BMD

ID, description, units MPD:53123   BMD   whole body bone mineral density (BMD)   [mg/cm2]  
Data set, strains Reed2   B6.129 and 129.B6 consomic w/par   9 strains     sex: both     age: 26wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Reed2 - whole body bone mineral density (BMD)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.0596   mg/cm2 0.0560   mg/cm2
Median of the strain means0.0615   mg/cm2 0.0567   mg/cm2
SD of the strain means± 0.00629 ± 0.00485
Coefficient of variation (CV)0.105 0.0866
Min–max range of strain means0.0509   –   0.0685   mg/cm2 0.0476   –   0.0628   mg/cm2
Mean sample size per strain18.0   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0009 0.0009 75.1051 < 0.0001
strain 8 0.0067 0.0008 68.5839 < 0.0001
sex:strain 8 0.0003 0.0 3.2042 0.0017
Residuals 280 0.0034 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3.B6By-Chr1 f 0.0617 0.00452   19 0.00104 0.0733 0.0542, 0.0683 0.33
129P3.B6By-Chr1 m 0.0572 0.00357   19 0.00082 0.0624 0.0488, 0.0628 0.24
129P3.B6By-Chr2 f 0.0665 0.00409   4 0.00205 0.0616 0.061, 0.0709 1.09
129P3.B6By-Chr2 m 0.0628 0.0041   5 0.00183 0.0653 0.0589, 0.069 1.4
129P3.B6By-Chr7 f 0.0615 0.00261   20 0.000585 0.0425 0.0557, 0.0664 0.3
129P3.B6By-Chr7 m 0.0567 0.0033   20 0.000738 0.0582 0.0492, 0.0646 0.14
129P3.B6By-Chr9 f 0.0685 0.00724   10 0.00229 0.106 0.0558, 0.0789 1.41
129P3.B6By-Chr9 m 0.0616 0.00402   11 0.00121 0.0653 0.0561, 0.0693 1.15
129P3/J f 0.0642 0.00478   24 0.000976 0.0745 0.0555, 0.0746 0.73
129P3/J m 0.059 0.00371   14 0.000992 0.063 0.0494, 0.0633 0.61
B6By.129P3-Chr2 f 0.0534 0.00198   16 0.000494 0.037 0.0497, 0.056 -0.99
B6By.129P3-Chr2 m 0.0515 0.00286   15 0.000738 0.0555 0.0477, 0.0578 -0.93
B6By.129P3-Chr7 f 0.0561 0.00307   20 0.000687 0.0547 0.0507, 0.0614 -0.56
B6By.129P3-Chr7 m 0.0535 0.00198   20 0.000443 0.037 0.0508, 0.0584 -0.52
B6By.129P3-Chr9 f 0.0509 0.0031   20 0.000693 0.0609 0.0457, 0.0573 -1.39
B6By.129P3-Chr9 m 0.0476 0.00201   19 0.00046 0.0421 0.0437, 0.052 -1.74
C57BL/6ByJ f 0.0538 0.00244   21 0.000532 0.0453 0.0492, 0.0575 -0.93
C57BL/6ByJ m 0.0543 0.00325   21 0.000709 0.0598 0.0498, 0.0624 -0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 f 0.0617 0.0008 0.0632 0.0601
129P3.B6By-Chr1 m 0.0572 0.0008 0.0588 0.0557
129P3.B6By-Chr2 f 0.0665 0.0017 0.0699 0.063
129P3.B6By-Chr2 m 0.0628 0.0016 0.0658 0.0597
129P3.B6By-Chr7 f 0.0615 0.0008 0.063 0.0599
129P3.B6By-Chr7 m 0.0567 0.0008 0.0582 0.0552
129P3.B6By-Chr9 f 0.0685 0.0011 0.0707 0.0664
129P3.B6By-Chr9 m 0.0616 0.0011 0.0637 0.0596
129P3/J f 0.0642 0.0007 0.0656 0.0628
129P3/J m 0.059 0.0009 0.0608 0.0571
B6By.129P3-Chr2 f 0.0534 0.0009 0.0552 0.0517
B6By.129P3-Chr2 m 0.0515 0.0009 0.0533 0.0497
B6By.129P3-Chr7 f 0.0561 0.0008 0.0576 0.0546
B6By.129P3-Chr7 m 0.0535 0.0008 0.055 0.052
B6By.129P3-Chr9 f 0.0509 0.0008 0.0524 0.0494
B6By.129P3-Chr9 m 0.0476 0.0008 0.0492 0.0461
C57BL/6ByJ f 0.0538 0.0008 0.0552 0.0523
C57BL/6ByJ m 0.0543 0.0008 0.0558 0.0528


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 both 0.0595 0.0006 0.0606 0.0583
129P3.B6By-Chr2 both 0.0646 0.0012 0.0669 0.0623
129P3.B6By-Chr7 both 0.0591 0.0006 0.0602 0.058
129P3.B6By-Chr9 both 0.0651 0.0008 0.0666 0.0636
129P3/J both 0.0616 0.0006 0.0627 0.0604
B6By.129P3-Chr2 both 0.0525 0.0006 0.0537 0.0513
B6By.129P3-Chr7 both 0.0548 0.0006 0.0559 0.0537
B6By.129P3-Chr9 both 0.0493 0.0006 0.0504 0.0482
C57BL/6ByJ both 0.054 0.0005 0.0551 0.053




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA