Phenotype measure:   Reed2   BMC

ID, description, units MPD:53122   BMC   whole body bone mineral content (BMC)   [mg]
Data set, strains Reed2   B6.129 and 129.B6 consomic w/par   9 strains     sex: both     age: 26wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Reed2 - whole body bone mineral content (BMC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.526   mg 0.481   mg
Median of the strain means0.523   mg 0.482   mg
SD of the strain means± 0.0793 ± 0.0550
Coefficient of variation (CV)0.151 0.114
Min–max range of strain means0.416   –   0.649   mg 0.405   –   0.558   mg
Mean sample size per strain18.0   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1379 0.1379 67.371 < 0.0001
strain 8 0.9138 0.1142 55.786 < 0.0001
sex:strain 8 0.0672 0.0084 4.1035 0.0001
Residuals 280 0.5733 0.002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3.B6By-Chr1 f 0.573 0.0539   19 0.0124 0.094 0.488, 0.663 0.59
129P3.B6By-Chr1 m 0.482 0.05   19 0.0115 0.104 0.37, 0.593 0.02
129P3.B6By-Chr2 f 0.605 0.0123   4 0.00617 0.0204 0.587, 0.614 0.99
129P3.B6By-Chr2 m 0.558 0.0474   5 0.0212 0.0849 0.514, 0.63 1.4
129P3.B6By-Chr7 f 0.523 0.0466   20 0.0104 0.0889 0.436, 0.604 -0.04
129P3.B6By-Chr7 m 0.48 0.0322   20 0.00721 0.0672 0.429, 0.542 -0.02
129P3.B6By-Chr9 f 0.649 0.0882   10 0.0279 0.136 0.51, 0.805 1.55
129P3.B6By-Chr9 m 0.558 0.029   11 0.00874 0.0519 0.519, 0.604 1.4
129P3/J f 0.562 0.0625   24 0.0128 0.111 0.439, 0.658 0.45
129P3/J m 0.496 0.0462   14 0.0123 0.0931 0.379, 0.553 0.27
B6By.129P3-Chr2 f 0.416 0.0294   16 0.00735 0.0706 0.375, 0.492 -1.39
B6By.129P3-Chr2 m 0.409 0.0477   15 0.0123 0.116 0.338, 0.489 -1.31
B6By.129P3-Chr7 f 0.503 0.0409   20 0.00915 0.0813 0.445, 0.594 -0.29
B6By.129P3-Chr7 m 0.493 0.0393   20 0.0088 0.0797 0.425, 0.578 0.22
B6By.129P3-Chr9 f 0.42 0.0447   20 0.00999 0.106 0.355, 0.505 -1.34
B6By.129P3-Chr9 m 0.405 0.0359   19 0.00825 0.0889 0.355, 0.47 -1.38
C57BL/6ByJ f 0.486 0.0361   21 0.00788 0.0743 0.411, 0.556 -0.51
C57BL/6ByJ m 0.449 0.0286   21 0.00625 0.0638 0.386, 0.5 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 f 0.5731 0.0104 0.5935 0.5526
129P3.B6By-Chr1 m 0.482 0.0104 0.5024 0.4616
129P3.B6By-Chr2 f 0.6052 0.0226 0.6498 0.5607
129P3.B6By-Chr2 m 0.5576 0.0202 0.5974 0.5178
129P3.B6By-Chr7 f 0.5235 0.0101 0.5434 0.5036
129P3.B6By-Chr7 m 0.48 0.0101 0.4999 0.46
129P3.B6By-Chr9 f 0.6492 0.0143 0.6774 0.621
129P3.B6By-Chr9 m 0.5583 0.0136 0.5851 0.5314
129P3/J f 0.5615 0.0092 0.5797 0.5434
129P3/J m 0.4961 0.0121 0.5199 0.4723
B6By.129P3-Chr2 f 0.4163 0.0113 0.4386 0.394
B6By.129P3-Chr2 m 0.4095 0.0117 0.4325 0.3865
B6By.129P3-Chr7 f 0.5032 0.0101 0.5231 0.4833
B6By.129P3-Chr7 m 0.4935 0.0101 0.5134 0.4735
B6By.129P3-Chr9 f 0.4203 0.0101 0.4402 0.4004
B6By.129P3-Chr9 m 0.4045 0.0104 0.425 0.3841
C57BL/6ByJ f 0.4859 0.0099 0.5053 0.4664
C57BL/6ByJ m 0.4485 0.0099 0.468 0.4291


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 both 0.5275 0.0073 0.542 0.5131
129P3.B6By-Chr2 both 0.5814 0.0152 0.6113 0.5515
129P3.B6By-Chr7 both 0.5017 0.0072 0.5158 0.4876
129P3.B6By-Chr9 both 0.6037 0.0099 0.6232 0.5843
129P3/J both 0.5288 0.0076 0.5438 0.5138
B6By.129P3-Chr2 both 0.4129 0.0081 0.4289 0.3969
B6By.129P3-Chr7 both 0.4983 0.0072 0.5124 0.4842
B6By.129P3-Chr9 both 0.4124 0.0072 0.4267 0.3981
C57BL/6ByJ both 0.4672 0.007 0.4809 0.4534




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA