Project measure / variable:   Reed2   bone_area

ID, description, units MPD:53121   bone_area   whole body bone area, head excluded   [cm2]  
Data set, strains Reed2   B6.129 and 129.B6 consomic w/par   9 strains     sex: both     age: 26wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Reed2 - whole body bone area, head excluded



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means8.80   cm2 8.57   cm2
Median of the strain means8.97   cm2 8.47   cm2
SD of the strain means± 0.532 ± 0.411
Coefficient of variation (CV)0.0605 0.0480
Min–max range of strain means7.80   –   9.47   cm2 7.93   –   9.23   cm2
Mean sample size per strain18.0   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.3366 3.3366 7.7523 0.0057
strain 8 42.89 5.3613 12.4565 < 0.0001
sex:strain 8 13.0479 1.631 3.7895 0.0003
Residuals 280 120.5116 0.4304


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3.B6By-Chr1 f 9.29 0.53   19 0.122 0.057 8.27, 10.0 0.91
129P3.B6By-Chr1 m 8.41 0.546   19 0.125 0.0649 7.57, 9.46 -0.4
129P3.B6By-Chr2 f 9.13 0.729   4 0.364 0.0798 8.28, 10.1 0.61
129P3.B6By-Chr2 m 8.88 0.258   5 0.115 0.029 8.45, 9.13 0.74
129P3.B6By-Chr7 f 8.51 0.558   20 0.125 0.0656 7.06, 9.61 -0.55
129P3.B6By-Chr7 m 8.47 0.48   20 0.107 0.0567 7.63, 9.35 -0.25
129P3.B6By-Chr9 f 9.47 0.658   10 0.208 0.0695 8.35, 10.5 1.25
129P3.B6By-Chr9 m 9.08 0.47   11 0.142 0.0517 8.44, 9.78 1.23
129P3/J f 8.76 0.902   24 0.184 0.103 7.13, 10.3 -0.08
129P3/J m 8.42 0.639   14 0.171 0.076 7.27, 9.54 -0.38
B6By.129P3-Chr2 f 7.8 0.473   16 0.118 0.0607 7.07, 9.05 -1.89
B6By.129P3-Chr2 m 7.93 0.583   15 0.15 0.0735 7.06, 9.02 -1.57
B6By.129P3-Chr7 f 8.97 0.836   20 0.187 0.0932 7.6, 11.2 0.31
B6By.129P3-Chr7 m 9.23 0.742   20 0.166 0.0803 8.13, 10.7 1.59
B6By.129P3-Chr9 f 8.26 0.699   20 0.156 0.0847 6.46, 9.3 -1.02
B6By.129P3-Chr9 m 8.47 0.706   19 0.162 0.0834 7.42, 9.82 -0.25
C57BL/6ByJ f 9.05 0.712   21 0.155 0.0787 7.71, 9.97 0.46
C57BL/6ByJ m 8.28 0.614   21 0.134 0.0741 7.05, 9.0 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 f 9.2895 0.1505 9.5857 8.9932
129P3.B6By-Chr1 m 8.41 0.1505 8.7063 8.1137
129P3.B6By-Chr2 f 9.1325 0.328 9.7782 8.4868
129P3.B6By-Chr2 m 8.88 0.2934 9.4575 8.3025
129P3.B6By-Chr7 f 8.5085 0.1467 8.7973 8.2197
129P3.B6By-Chr7 m 8.472 0.1467 8.7608 8.1832
129P3.B6By-Chr9 f 9.472 0.2075 9.8804 9.0636
129P3.B6By-Chr9 m 9.0782 0.1978 9.4676 8.6888
129P3/J f 8.7629 0.1339 9.0265 8.4993
129P3/J m 8.4179 0.1753 8.763 8.0727
B6By.129P3-Chr2 f 7.7963 0.164 8.1191 7.4734
B6By.129P3-Chr2 m 7.9287 0.1694 8.2621 7.5952
B6By.129P3-Chr7 f 8.9725 0.1467 9.2613 8.6837
B6By.129P3-Chr7 m 9.233 0.1467 9.5218 8.9442
B6By.129P3-Chr9 f 8.2575 0.1467 8.5463 7.9687
B6By.129P3-Chr9 m 8.4674 0.1505 8.7636 8.1711
C57BL/6ByJ f 9.0505 0.1432 9.3323 8.7687
C57BL/6ByJ m 8.2771 0.1432 8.559 7.9953


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3.B6By-Chr1 both 8.8497 0.1064 9.0592 8.6402
129P3.B6By-Chr2 both 9.0063 0.22 9.4394 8.5731
129P3.B6By-Chr7 both 8.4903 0.1037 8.6944 8.2861
129P3.B6By-Chr9 both 9.2751 0.1433 9.5572 8.993
129P3/J both 8.5904 0.1103 8.8075 8.3732
B6By.129P3-Chr2 both 7.8625 0.1179 8.0945 7.6304
B6By.129P3-Chr7 both 9.1028 0.1037 9.3069 8.8986
B6By.129P3-Chr9 both 8.3624 0.1051 8.5693 8.1556
C57BL/6ByJ both 8.6638 0.1012 8.8631 8.4645




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA