Project measure / variable:   HMDPpheno8   beta_HOC

ID, description, units MPD:50386   beta_HOC   liver 7-beta-hydroxycholesterol (16h fast), relative abundance    
Data set, strains HMDPpheno8   HMDP   105 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver 7-beta-hydroxycholesterol (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested105 strains
Mean of the strain means106174   None
Median of the strain means97369   None
SD of the strain means± 39869
Coefficient of variation (CV)0.376
Min–max range of strain means26119   –   249068   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 45929857961.8132 2187136093.4197 1.6175 0.1034
Residuals 34 45974813575.6812 1352200399.2847


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 92334.0 0.0   1   0.0 0.0 92334.0, 92334.0 -0.35
A/J m 105810.0 35581.0   2   25159.0 0.336 80651.0, 130969.0 -0.01
AKR/J m 126587.0 0.0   1   0.0 0.0 126587.0, 126587.0 0.51
AXB10/PgnJ m 65430.0 0.0   1   0.0 0.0 65430.0, 65430.0 -1.02
AXB12/PgnJ m 60599.0 0.0   1   0.0 0.0 60599.0, 60599.0 -1.14
AXB13/PgnJ m 37480.0 0.0   1   0.0 0.0 37480.0, 37480.0 -1.72
AXB15/PgnJ m 96671.0 0.0   1   0.0 0.0 96671.0, 96671.0 -0.24
AXB19a/PgnJ m 129817.0 0.0   1   0.0 0.0 129817.0, 129817.0 0.59
AXB19b/PgnJ m 54465.0 2779.0   2   1965.0 0.051 52500.0, 56430.0 -1.3
AXB19/PgnJ m 76954.0 0.0   1   0.0 0.0 76954.0, 76954.0 -0.73
AXB23/PgnJ m 82479.0 0.0   1   0.0 0.0 82479.0, 82479.0 -0.59
AXB24/PgnJ m 76439.0 13497.0   2   9544.0 0.177 66895.0, 85983.0 -0.75
AXB2/PgnJ m 104645.0 0.0   1   0.0 0.0 104645.0, 104645.0 -0.04
AXB4/PgnJ m 116343.0 0.0   1   0.0 0.0 116343.0, 116343.0 0.26
AXB5/PgnJ m 77016.0 0.0   1   0.0 0.0 77016.0, 77016.0 -0.73
AXB6/PgnJ m 64565.0 0.0   1   0.0 0.0 64565.0, 64565.0 -1.04
AXB8/PgnJ m 83647.0 0.0   1   0.0 0.0 83647.0, 83647.0 -0.57
BALB/cJ m 138115.0 99882.0   3 57667.0 0.723 71515.0, 252961.0 0.8
BTBR T+ Itpr3tf/J m 150084.0 0.0   1   0.0 0.0 150084.0, 150084.0 1.1
BUB/BnJ m 108056.0 0.0   1   0.0 0.0 108056.0, 108056.0 0.05
BXA11/PgnJ m 77921.0 0.0   1   0.0 0.0 77921.0, 77921.0 -0.71
BXA12/PgnJ m 78779.0 0.0   1   0.0 0.0 78779.0, 78779.0 -0.69
BXA13/PgnJ m 88557.0 0.0   1   0.0 0.0 88557.0, 88557.0 -0.44
BXA14/PgnJ m 75680.0 0.0   1   0.0 0.0 75680.0, 75680.0 -0.76
BXA16/PgnJ m 146349.0 61567.0   2   43535.0 0.421 102815.0, 189884.0 1.01
BXA1/PgnJ m 73106.0 0.0   1   0.0 0.0 73106.0, 73106.0 -0.83
BXA24/PgnJ m 97760.0 0.0   1   0.0 0.0 97760.0, 97760.0 -0.21
BXA25/PgnJ m 43619.0 0.0   1   0.0 0.0 43619.0, 43619.0 -1.57
BXA26/PgnJ m 57374.0 0.0   1   0.0 0.0 57374.0, 57374.0 -1.22
BXA2/PgnJ m 85499.0 0.0   1   0.0 0.0 85499.0, 85499.0 -0.52
BXA4/PgnJ m 249068.0 0.0   1   0.0 0.0 249068.0, 249068.0 3.58
BXA7/PgnJ m 75727.0 0.0   1   0.0 0.0 75727.0, 75727.0 -0.76
BXA8/PgnJ m 57318.0 0.0   1   0.0 0.0 57318.0, 57318.0 -1.23
BXD11/TyJ m 95222.0 0.0   1   0.0 0.0 95222.0, 95222.0 -0.27
BXD12/TyJ m 66737.0 0.0   1   0.0 0.0 66737.0, 66737.0 -0.99
BXD13/TyJ m 132244.0 0.0   1   0.0 0.0 132244.0, 132244.0 0.65
BXD14/TyJ m 97369.0 0.0   1   0.0 0.0 97369.0, 97369.0 -0.22
BXD15/TyJ m 162574.0 0.0   1   0.0 0.0 162574.0, 162574.0 1.41
BXD18/TyJ m 173686.0 0.0   1   0.0 0.0 173686.0, 173686.0 1.69
BXD19/TyJ m 116059.0 43956.0   2   31082.0 0.379 84977.0, 147140.0 0.25
BXD1/TyJ m 85479.0 0.0   1   0.0 0.0 85479.0, 85479.0 -0.52
BXD20/TyJ m 179673.0 0.0   1   0.0 0.0 179673.0, 179673.0 1.84
BXD21/TyJ m 101241.0 0.0   1   0.0 0.0 101241.0, 101241.0 -0.12
BXD22/TyJ m 85722.0 0.0   1   0.0 0.0 85722.0, 85722.0 -0.51
BXD24/TyJ m 83367.0 0.0   1   0.0 0.0 83367.0, 83367.0 -0.57
BXD24/TyJ-Cep290rd16/J m 172018.0 0.0   1   0.0 0.0 172018.0, 172018.0 1.65
BXD28/TyJ m 122268.0 2835.0   2   2005.0 0.0232 120263.0, 124273.0 0.4
BXD29-Tlr4lps-2J/J m 54938.0 0.0   1   0.0 0.0 54938.0, 54938.0 -1.29
BXD2/TyJ m 147463.0 0.0   1   0.0 0.0 147463.0, 147463.0 1.04
BXD32/TyJ m 100607.0 0.0   1   0.0 0.0 100607.0, 100607.0 -0.14
BXD33/TyJ m 126140.0 0.0   1   0.0 0.0 126140.0, 126140.0 0.5
BXD34/TyJ m 85094.0 0.0   1   0.0 0.0 85094.0, 85094.0 -0.53
BXD36/TyJ m 99738.0 0.0   1   0.0 0.0 99738.0, 99738.0 -0.16
BXD38/TyJ m 94859.0 0.0   1   0.0 0.0 94859.0, 94859.0 -0.28
BXD39/TyJ m 80794.0 0.0   1   0.0 0.0 80794.0, 80794.0 -0.64
BXD40/TyJ m 118855.0 0.0   1   0.0 0.0 118855.0, 118855.0 0.32
BXD42/TyJ m 116186.0 0.0   1   0.0 0.0 116186.0, 116186.0 0.25
BXD5/TyJ m 93037.0 0.0   1   0.0 0.0 93037.0, 93037.0 -0.33
BXD6/TyJ m 116235.0 0.0   1   0.0 0.0 116235.0, 116235.0 0.25
BXD8/TyJ m 85692.0 0.0   1   0.0 0.0 85692.0, 85692.0 -0.51
BXD9/TyJ m 107177.0 0.0   1   0.0 0.0 107177.0, 107177.0 0.03
BXH10/TyJ m 42995.0 0.0   1   0.0 0.0 42995.0, 42995.0 -1.58
BXH19/TyJ m 167435.0 0.0   1   0.0 0.0 167435.0, 167435.0 1.54
BXH20/KccJ m 204348.0 0.0   1   0.0 0.0 204348.0, 204348.0 2.46
BXH22/KccJ m 114735.0 0.0   1   0.0 0.0 114735.0, 114735.0 0.21
BXH2/TyJ m 118600.0 0.0   1   0.0 0.0 118600.0, 118600.0 0.31
BXH4/TyJ m 111050.0 73340.0   2   51859.0 0.66 59190.0, 162909.0 0.12
BXH6/TyJ m 134875.0 0.0   1   0.0 0.0 134875.0, 134875.0 0.72
BXH7/TyJ m 90181.0 0.0   1   0.0 0.0 90181.0, 90181.0 -0.4
BXH8/TyJ m 179170.0 0.0   1   0.0 0.0 179170.0, 179170.0 1.83
BXH9/TyJ m 130168.0 0.0   1   0.0 0.0 130168.0, 130168.0 0.6
C3H/HeJ m 128606.0 43499.0   2   30758.0 0.338 97848.0, 159364.0 0.56
C57BL/6J m 65030.0 13599.0   5 6082.0 0.209 53516.0, 88469.0 -1.03
C57L/J m 93772.0 0.0   1   0.0 0.0 93772.0, 93772.0 -0.31
C58/J m 26119.0 0.0   1   0.0 0.0 26119.0, 26119.0 -2.01
CAST/EiJ m 88458.0 0.0   1   0.0 0.0 88458.0, 88458.0 -0.44
CBA/J m 65111.0 0.0   1   0.0 0.0 65111.0, 65111.0 -1.03
CE/J m 64568.0 0.0   1   0.0 0.0 64568.0, 64568.0 -1.04
CXB11/HiAJ m 92877.0 35171.0   2   24870.0 0.379 68007.0, 117746.0 -0.33
CXB12/HiAJ m 92711.0 4064.0   2   2874.0 0.0438 89837.0, 95584.0 -0.34
CXB13/HiAJ m 115926.0 23519.0   3 13579.0 0.203 88789.0, 130409.0 0.24
CXB1/ByJ m 106395.0 14519.0   3 8382.0 0.136 93704.0, 122227.0 0.01
CXB2/ByJ m 92434.0 15584.0   3 8997.0 0.169 79860.0, 109869.0 -0.34
CXB3/ByJ m 148230.0 5454.0   2   3856.0 0.0368 144374.0, 152086.0 1.05
CXB4/ByJ m 98847.0 9825.0   2   6947.0 0.0994 91899.0, 105794.0 -0.18
CXB6/ByJ m 74514.0 7174.0   3 4142.0 0.0963 68709.0, 82535.0 -0.79
CXB7/ByJ m 87482.0 29542.0   2   20889.0 0.338 66593.0, 108372.0 -0.47
CXB8/HiAJ m 93473.0 36655.0   3 21163.0 0.392 64358.0, 134635.0 -0.32
CXB9/HiAJ m 65338.0 13926.0   3 8040.0 0.213 55082.0, 81192.0 -1.02
DBA/2J m 152363.0 33569.0   4 16784.0 0.22 104735.0, 182006.0 1.16
FVB/NJ m 247738.0 0.0   1   0.0 0.0 247738.0, 247738.0 3.55
I/LnJ m 118275.0 0.0   1   0.0 0.0 118275.0, 118275.0 0.3
KK/HlJ m 137657.0 0.0   1   0.0 0.0 137657.0, 137657.0 0.79
LG/J m 155182.0 0.0   1   0.0 0.0 155182.0, 155182.0 1.23
LP/J m 119874.0 0.0   1   0.0 0.0 119874.0, 119874.0 0.34
MA/MyJ m 107510.0 0.0   1   0.0 0.0 107510.0, 107510.0 0.03
NOD/ShiLtJ m 87439.0 0.0   1   0.0 0.0 87439.0, 87439.0 -0.47
NON/ShiLtJ m 119157.0 0.0   1   0.0 0.0 119157.0, 119157.0 0.33
NZW/LacJ m 77816.0 0.0   1   0.0 0.0 77816.0, 77816.0 -0.71
PL/J m 140801.0 0.0   1   0.0 0.0 140801.0, 140801.0 0.87
RIIIS/J m 160373.0 0.0   1   0.0 0.0 160373.0, 160373.0 1.36
SEA/GnJ m 105283.0 0.0   1   0.0 0.0 105283.0, 105283.0 -0.02
SJL/J m 94262.0 0.0   1   0.0 0.0 94262.0, 94262.0 -0.3
SM/J m 96182.0 0.0   1   0.0 0.0 96182.0, 96182.0 -0.25
SWR/J m 180123.0 0.0   1   0.0 0.0 180123.0, 180123.0 1.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 105809.95 26001.9268 158652.2231 52967.6769
AXB19b/PgnJ m 54465.0 26001.9268 107307.2731 1622.7269
AXB24/PgnJ m 76438.85 26001.9268 129281.1231 23596.5769
BALB/cJ m 138115.2333 21230.4844 181260.7686 94969.698
BXA16/PgnJ m 146349.35 26001.9268 199191.6231 93507.0769
BXD19/TyJ m 116058.9 26001.9268 168901.1731 63216.6269
BXD28/TyJ m 122268.15 26001.9268 175110.4231 69425.8769
BXH4/TyJ m 111049.8 26001.9268 163892.0731 58207.5269
C3H/HeJ m 128606.1 26001.9268 181448.3731 75763.8269
C57BL/6J m 65029.94 16445.0625 98450.3279 31609.5521
CXB11/HiAJ m 92876.55 26001.9268 145718.8231 40034.2769
CXB12/HiAJ m 92710.6 26001.9268 145552.8731 39868.3269
CXB13/HiAJ m 115925.9333 21230.4844 159071.4686 72780.398
CXB1/ByJ m 106395.0667 21230.4844 149540.602 63249.5314
CXB2/ByJ m 92434.2333 21230.4844 135579.7686 49288.698
CXB3/ByJ m 148229.95 26001.9268 201072.2231 95387.6769
CXB4/ByJ m 98846.7 26001.9268 151688.9731 46004.4269
CXB6/ByJ m 74514.4 21230.4844 117659.9353 31368.8647
CXB7/ByJ m 87482.25 26001.9268 140324.5231 34639.9769
CXB8/HiAJ m 93472.7 21230.4844 136618.2353 50327.1647
CXB9/HiAJ m 65337.8 21230.4844 108483.3353 22192.2647
DBA/2J m 152363.075 18386.1388 189728.2046 114997.9454




  GWAS USING LINEAR MIXED MODELS