Project measure / variable:   HMDPpheno8   alpha_HOC

ID, description, units MPD:50385   alpha_HOC   liver 7-alpha-hydroxycholesterol (16h fast), relative abundance    
Data set, strains HMDPpheno8   HMDP   105 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver 7-alpha-hydroxycholesterol (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested105 strains
Mean of the strain means77433   None
Median of the strain means73542   None
SD of the strain means± 32099
Coefficient of variation (CV)0.415
Min–max range of strain means10624   –   212670   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 28145194687.8298 1407259734.3915 2.1233 0.0278
Residuals 32 21208497027.06 662765532.0956


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 75877.0 0.0   1   0.0 0.0 75877.0, 75877.0 -0.05
A/J m 85166.0 26469.0   2   18716.0 0.311 66449.0, 103882.0 0.24
AKR/J m 115416.0 0.0   1   0.0 0.0 115416.0, 115416.0 1.18
AXB10/PgnJ m 61429.0 0.0   1   0.0 0.0 61429.0, 61429.0 -0.5
AXB12/PgnJ m 66670.0 0.0   1   0.0 0.0 66670.0, 66670.0 -0.34
AXB13/PgnJ m 43478.0 0.0   1   0.0 0.0 43478.0, 43478.0 -1.06
AXB15/PgnJ m 56334.0 0.0   1   0.0 0.0 56334.0, 56334.0 -0.66
AXB19a/PgnJ m 46498.0 0.0   1   0.0 0.0 46498.0, 46498.0 -0.96
AXB19b/PgnJ m 25648.0 11533.0   2   8155.0 0.45 17494.0, 33803.0 -1.61
AXB19/PgnJ m 37645.0 0.0   1   0.0 0.0 37645.0, 37645.0 -1.24
AXB1/PgnJ m 17568.0 0.0   1   0.0 0.0 17568.0, 17568.0 -1.87
AXB23/PgnJ m 71593.0 0.0   1   0.0 0.0 71593.0, 71593.0 -0.18
AXB24/PgnJ m 62466.0 0.0   1   0.0 0.0 62466.0, 62466.0 -0.47
AXB2/PgnJ m 75520.0 0.0   1   0.0 0.0 75520.0, 75520.0 -0.06
AXB4/PgnJ m 62415.0 0.0   1   0.0 0.0 62415.0, 62415.0 -0.47
AXB5/PgnJ m 47339.0 0.0   1   0.0 0.0 47339.0, 47339.0 -0.94
AXB6/PgnJ m 32363.0 0.0   1   0.0 0.0 32363.0, 32363.0 -1.4
AXB8/PgnJ m 79206.0 0.0   1   0.0 0.0 79206.0, 79206.0 0.06
BALB/cJ m 138009.0 50572.0   3 29198.0 0.366 106456.0, 196339.0 1.89
BTBR T+ Itpr3tf/J m 123718.0 0.0   1   0.0 0.0 123718.0, 123718.0 1.44
BUB/BnJ m 74361.0 0.0   1   0.0 0.0 74361.0, 74361.0 -0.1
BXA11/PgnJ m 65485.0 0.0   1   0.0 0.0 65485.0, 65485.0 -0.37
BXA12/PgnJ m 70327.0 0.0   1   0.0 0.0 70327.0, 70327.0 -0.22
BXA13/PgnJ m 59500.0 0.0   1   0.0 0.0 59500.0, 59500.0 -0.56
BXA14/PgnJ m 34917.0 0.0   1   0.0 0.0 34917.0, 34917.0 -1.32
BXA16/PgnJ m 80458.0 14736.0   2   10420.0 0.183 70038.0, 90878.0 0.09
BXA1/PgnJ m 73266.0 0.0   1   0.0 0.0 73266.0, 73266.0 -0.13
BXA24/PgnJ m 55081.0 0.0   1   0.0 0.0 55081.0, 55081.0 -0.7
BXA25/PgnJ m 82852.0 0.0   1   0.0 0.0 82852.0, 82852.0 0.17
BXA26/PgnJ m 46779.0 0.0   1   0.0 0.0 46779.0, 46779.0 -0.96
BXA2/PgnJ m 44744.0 0.0   1   0.0 0.0 44744.0, 44744.0 -1.02
BXA4/PgnJ m 212670.0 0.0   1   0.0 0.0 212670.0, 212670.0 4.21
BXA7/PgnJ m 57056.0 0.0   1   0.0 0.0 57056.0, 57056.0 -0.63
BXA8/PgnJ m 51391.0 0.0   1   0.0 0.0 51391.0, 51391.0 -0.81
BXD11/TyJ m 64917.0 0.0   1   0.0 0.0 64917.0, 64917.0 -0.39
BXD12/TyJ m 58819.0 0.0   1   0.0 0.0 58819.0, 58819.0 -0.58
BXD13/TyJ m 94312.0 0.0   1   0.0 0.0 94312.0, 94312.0 0.53
BXD14/TyJ m 55566.0 0.0   1   0.0 0.0 55566.0, 55566.0 -0.68
BXD15/TyJ m 112371.0 0.0   1   0.0 0.0 112371.0, 112371.0 1.09
BXD18/TyJ m 92887.0 0.0   1   0.0 0.0 92887.0, 92887.0 0.48
BXD19/TyJ m 78647.0 23762.0   2   16802.0 0.302 61845.0, 95450.0 0.04
BXD1/TyJ m 55696.0 0.0   1   0.0 0.0 55696.0, 55696.0 -0.68
BXD20/TyJ m 143265.0 0.0   1   0.0 0.0 143265.0, 143265.0 2.05
BXD21/TyJ m 64971.0 0.0   1   0.0 0.0 64971.0, 64971.0 -0.39
BXD22/TyJ m 76704.0 0.0   1   0.0 0.0 76704.0, 76704.0 -0.02
BXD24/TyJ m 74648.0 0.0   1   0.0 0.0 74648.0, 74648.0 -0.09
BXD24/TyJ-Cep290rd16/J m 151050.0 0.0   1   0.0 0.0 151050.0, 151050.0 2.29
BXD28/TyJ m 66134.0 5488.0   2   3880.0 0.083 62254.0, 70014.0 -0.35
BXD29-Tlr4lps-2J/J m 35960.0 0.0   1   0.0 0.0 35960.0, 35960.0 -1.29
BXD2/TyJ m 112724.0 0.0   1   0.0 0.0 112724.0, 112724.0 1.1
BXD32/TyJ m 29518.0 0.0   1   0.0 0.0 29518.0, 29518.0 -1.49
BXD33/TyJ m 107714.0 0.0   1   0.0 0.0 107714.0, 107714.0 0.94
BXD34/TyJ m 64800.0 0.0   1   0.0 0.0 64800.0, 64800.0 -0.39
BXD36/TyJ m 80382.0 0.0   1   0.0 0.0 80382.0, 80382.0 0.09
BXD38/TyJ m 69033.0 0.0   1   0.0 0.0 69033.0, 69033.0 -0.26
BXD39/TyJ m 100257.0 0.0   1   0.0 0.0 100257.0, 100257.0 0.71
BXD40/TyJ m 67783.0 0.0   1   0.0 0.0 67783.0, 67783.0 -0.3
BXD42/TyJ m 71703.0 0.0   1   0.0 0.0 71703.0, 71703.0 -0.18
BXD5/TyJ m 86206.0 0.0   1   0.0 0.0 86206.0, 86206.0 0.27
BXD6/TyJ m 16528.0 0.0   1   0.0 0.0 16528.0, 16528.0 -1.9
BXD8/TyJ m 73542.0 0.0   1   0.0 0.0 73542.0, 73542.0 -0.12
BXD9/TyJ m 80639.0 0.0   1   0.0 0.0 80639.0, 80639.0 0.1
BXH10/TyJ m 34349.0 0.0   1   0.0 0.0 34349.0, 34349.0 -1.34
BXH19/TyJ m 123016.0 0.0   1   0.0 0.0 123016.0, 123016.0 1.42
BXH20/KccJ m 135908.0 0.0   1   0.0 0.0 135908.0, 135908.0 1.82
BXH22/KccJ m 70005.0 0.0   1   0.0 0.0 70005.0, 70005.0 -0.23
BXH2/TyJ m 103934.0 0.0   1   0.0 0.0 103934.0, 103934.0 0.83
BXH4/TyJ m 82596.0 8588.0   2   6073.0 0.104 76524.0, 88669.0 0.16
BXH6/TyJ m 91718.0 0.0   1   0.0 0.0 91718.0, 91718.0 0.45
BXH7/TyJ m 69770.0 0.0   1   0.0 0.0 69770.0, 69770.0 -0.24
BXH8/TyJ m 94789.0 0.0   1   0.0 0.0 94789.0, 94789.0 0.54
BXH9/TyJ m 123174.0 0.0   1   0.0 0.0 123174.0, 123174.0 1.43
C3H/HeJ m 100979.0 40204.0   2   28429.0 0.398 72550.0, 129408.0 0.73
C57BL/6J m 55598.0 21562.0   4 10781.0 0.388 31682.0, 81574.0 -0.68
C57L/J m 70856.0 0.0   1   0.0 0.0 70856.0, 70856.0 -0.2
C58/J m 10624.0 0.0   1   0.0 0.0 10624.0, 10624.0 -2.08
CAST/EiJ m 75730.0 0.0   1   0.0 0.0 75730.0, 75730.0 -0.05
CE/J m 103327.0 0.0   1   0.0 0.0 103327.0, 103327.0 0.81
CXB11/HiAJ m 74180.0 33061.0   2   23378.0 0.446 50802.0, 97558.0 -0.1
CXB12/HiAJ m 70968.0 8559.0   2   6052.0 0.121 64916.0, 77020.0 -0.2
CXB13/HiAJ m 89848.0 42432.0   3 24498.0 0.472 42141.0, 123371.0 0.39
CXB1/ByJ m 63324.0 13183.0   3 7611.0 0.208 48129.0, 71703.0 -0.44
CXB2/ByJ m 64801.0 26149.0   3 15097.0 0.404 42946.0, 93772.0 -0.39
CXB3/ByJ m 90162.0 21720.0   2   15359.0 0.241 74803.0, 105520.0 0.4
CXB4/ByJ m 83273.0 3869.0   2   2735.0 0.0465 80538.0, 86008.0 0.18
CXB6/ByJ m 47100.0 5227.0   3 3018.0 0.111 41135.0, 50881.0 -0.95
CXB7/ByJ m 55409.0 23044.0   2   16294.0 0.416 39114.0, 71703.0 -0.69
CXB8/HiAJ m 68893.0 18941.0   3 10936.0 0.275 50678.0, 88485.0 -0.27
CXB9/HiAJ m 43920.0 10153.0   3 5862.0 0.231 33616.0, 53916.0 -1.04
DBA/2J m 77787.0 31008.0   4 15504.0 0.399 31728.0, 99142.0 0.01
FVB/NJ m 118734.0 0.0   1   0.0 0.0 118734.0, 118734.0 1.29
I/LnJ m 76890.0 0.0   1   0.0 0.0 76890.0, 76890.0 -0.02
KK/HlJ m 81036.0 0.0   1   0.0 0.0 81036.0, 81036.0 0.11
LG/J m 97927.0 0.0   1   0.0 0.0 97927.0, 97927.0 0.64
LP/J m 106493.0 0.0   1   0.0 0.0 106493.0, 106493.0 0.91
MA/MyJ m 98528.0 0.0   1   0.0 0.0 98528.0, 98528.0 0.66
NOD/ShiLtJ m 86905.0 0.0   1   0.0 0.0 86905.0, 86905.0 0.3
NON/ShiLtJ m 98624.0 0.0   1   0.0 0.0 98624.0, 98624.0 0.66
NZW/LacJ m 66191.0 0.0   1   0.0 0.0 66191.0, 66191.0 -0.35
PL/J m 83202.0 0.0   1   0.0 0.0 83202.0, 83202.0 0.18
RIIIS/J m 148828.0 0.0   1   0.0 0.0 148828.0, 148828.0 2.22
SEA/GnJ m 64388.0 0.0   1   0.0 0.0 64388.0, 64388.0 -0.41
SJL/J m 63592.0 0.0   1   0.0 0.0 63592.0, 63592.0 -0.43
SM/J m 80394.0 0.0   1   0.0 0.0 80394.0, 80394.0 0.09
SWR/J m 162712.0 0.0   1   0.0 0.0 162712.0, 162712.0 2.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 85165.55 18203.9217 122245.7251 48085.3749
AXB19b/PgnJ m 25648.25 18203.9217 62728.4251 0.0
BALB/cJ m 138009.2333 14863.4398 168285.0696 107733.3971
BXA16/PgnJ m 80458.4 18203.9217 117538.5751 43378.2249
BXD19/TyJ m 78647.4 18203.9217 115727.5751 41567.2249
BXD28/TyJ m 66134.05 18203.9217 103214.2251 29053.8749
BXH4/TyJ m 82596.4 18203.9217 119676.5751 45516.2249
C3H/HeJ m 100979.05 18203.9217 138059.2251 63898.8749
C57BL/6J m 55598.45 12872.1165 81818.0933 29378.8067
CXB11/HiAJ m 74179.8 18203.9217 111259.9751 37099.6249
CXB12/HiAJ m 70967.65 18203.9217 108047.8251 33887.4749
CXB13/HiAJ m 89848.0 14863.4398 120123.8362 59572.1638
CXB1/ByJ m 63324.3 14863.4398 93600.1362 33048.4638
CXB2/ByJ m 64801.3333 14863.4398 95077.1696 34525.4971
CXB3/ByJ m 90161.5 18203.9217 127241.6751 53081.3249
CXB4/ByJ m 83272.95 18203.9217 120353.1251 46192.7749
CXB6/ByJ m 47099.8 14863.4398 77375.6362 16823.9638
CXB7/ByJ m 55408.8 18203.9217 92488.9751 18328.6249
CXB8/HiAJ m 68893.3333 14863.4398 99169.1696 38617.4971
CXB9/HiAJ m 43919.9 14863.4398 74195.7362 13644.0638
DBA/2J m 77787.2 12872.1165 104006.8433 51567.5567




  GWAS USING LINEAR MIXED MODELS