Phenotype measure:   HMDPpheno8   sphingosine

ID, description, units MPD:50384   sphingosine   liver sphingosine (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver sphingosine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means459305   None
Median of the strain means272868   None
SD of the strain means± 459754
Coefficient of variation (CV)1.00
Min–max range of strain means55721   –   2915742   None
Mean sample size per strain1.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 17 4098920493211.21 241112970188.895 2.5456 0.0156
Residuals 26 2462628377793.51 94716476068.9813


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 494616.0 0.0   1   0.0 0.0 494616.0, 494616.0 0.08
A/J m 154273.0 116828.0   2   82610.0 0.757 71663.0, 236883.0 -0.66
AXB10/PgnJ m 187210.0 0.0   1   0.0 0.0 187210.0, 187210.0 -0.59
AXB12/PgnJ m 184597.0 0.0   1   0.0 0.0 184597.0, 184597.0 -0.6
AXB13/PgnJ m 55721.0 0.0   1   0.0 0.0 55721.0, 55721.0 -0.88
AXB15/PgnJ m 60734.0 0.0   1   0.0 0.0 60734.0, 60734.0 -0.87
AXB19a/PgnJ m 475307.0 0.0   1   0.0 0.0 475307.0, 475307.0 0.03
AXB19b/PgnJ m 1595482.0 884482.0   2   625423.0 0.554 970059.0, 2220906.0 2.47
AXB19/PgnJ m 1010064.0 0.0   1   0.0 0.0 1010064.0, 1010064.0 1.2
AXB1/PgnJ m 2915742.0 0.0   1   0.0 0.0 2915742.0, 2915742.0 5.34
AXB23/PgnJ m 356501.0 0.0   1   0.0 0.0 356501.0, 356501.0 -0.22
AXB24/PgnJ m 262816.0 0.0   1   0.0 0.0 262816.0, 262816.0 -0.43
AXB2/PgnJ m 478203.0 0.0   1   0.0 0.0 478203.0, 478203.0 0.04
AXB4/PgnJ m 474296.0 0.0   1   0.0 0.0 474296.0, 474296.0 0.03
AXB5/PgnJ m 117132.0 0.0   1   0.0 0.0 117132.0, 117132.0 -0.74
AXB6/PgnJ m 271382.0 0.0   1   0.0 0.0 271382.0, 271382.0 -0.41
AXB8/PgnJ m 213050.0 0.0   1   0.0 0.0 213050.0, 213050.0 -0.54
BALB/cJ m 216064.0 66466.0   3 38374.0 0.308 139485.0, 258781.0 -0.53
BTBR T+ Itpr3tf/J m 271799.0 0.0   1   0.0 0.0 271799.0, 271799.0 -0.41
BUB/BnJ m 451120.0 0.0   1   0.0 0.0 451120.0, 451120.0 -0.02
BXA11/PgnJ m 94478.0 0.0   1   0.0 0.0 94478.0, 94478.0 -0.79
BXA12/PgnJ m 189157.0 0.0   1   0.0 0.0 189157.0, 189157.0 -0.59
BXA13/PgnJ m 1473567.0 0.0   1   0.0 0.0 1473567.0, 1473567.0 2.21
BXA14/PgnJ m 1243738.0 0.0   1   0.0 0.0 1243738.0, 1243738.0 1.71
BXA16/PgnJ m 198500.0 41008.0   2   28997.0 0.207 169504.0, 227497.0 -0.57
BXA1/PgnJ m 129167.0 0.0   1   0.0 0.0 129167.0, 129167.0 -0.72
BXA24/PgnJ m 308559.0 0.0   1   0.0 0.0 308559.0, 308559.0 -0.33
BXA25/PgnJ m 138960.0 0.0   1   0.0 0.0 138960.0, 138960.0 -0.7
BXA26/PgnJ m 522280.0 0.0   1   0.0 0.0 522280.0, 522280.0 0.14
BXA2/PgnJ m 212409.0 0.0   1   0.0 0.0 212409.0, 212409.0 -0.54
BXA4/PgnJ m 393058.0 0.0   1   0.0 0.0 393058.0, 393058.0 -0.14
BXA7/PgnJ m 232534.0 0.0   1   0.0 0.0 232534.0, 232534.0 -0.49
BXA8/PgnJ m 184723.0 0.0   1   0.0 0.0 184723.0, 184723.0 -0.6
BXD11/TyJ m 149305.0 0.0   1   0.0 0.0 149305.0, 149305.0 -0.67
BXD12/TyJ m 1158832.0 0.0   1   0.0 0.0 1158832.0, 1158832.0 1.52
BXD13/TyJ m 202439.0 0.0   1   0.0 0.0 202439.0, 202439.0 -0.56
BXD14/TyJ m 581783.0 0.0   1   0.0 0.0 581783.0, 581783.0 0.27
BXD15/TyJ m 325159.0 0.0   1   0.0 0.0 325159.0, 325159.0 -0.29
BXD18/TyJ m 145962.0 0.0   1   0.0 0.0 145962.0, 145962.0 -0.68
BXD19/TyJ m 255127.0 22988.0   2   16255.0 0.0901 238873.0, 271382.0 -0.44
BXD20/TyJ m 654514.0 0.0   1   0.0 0.0 654514.0, 654514.0 0.42
BXD21/TyJ m 91115.0 0.0   1   0.0 0.0 91115.0, 91115.0 -0.8
BXD22/TyJ m 520479.0 0.0   1   0.0 0.0 520479.0, 520479.0 0.13
BXD24/TyJ m 175645.0 0.0   1   0.0 0.0 175645.0, 175645.0 -0.62
BXD24/TyJ-Cep290rd16/J m 261944.0 0.0   1   0.0 0.0 261944.0, 261944.0 -0.43
BXD28/TyJ m 213700.0 29972.0   2   21193.0 0.14 192507.0, 234894.0 -0.53
BXD29-Tlr4lps-2J/J m 331615.0 0.0   1   0.0 0.0 331615.0, 331615.0 -0.28
BXD2/TyJ m 743578.0 0.0   1   0.0 0.0 743578.0, 743578.0 0.62
BXD32/TyJ m 121597.0 0.0   1   0.0 0.0 121597.0, 121597.0 -0.73
BXD33/TyJ m 877172.0 0.0   1   0.0 0.0 877172.0, 877172.0 0.91
BXD34/TyJ m 240433.0 0.0   1   0.0 0.0 240433.0, 240433.0 -0.48
BXD36/TyJ m 158860.0 0.0   1   0.0 0.0 158860.0, 158860.0 -0.65
BXD38/TyJ m 268828.0 0.0   1   0.0 0.0 268828.0, 268828.0 -0.41
BXD39/TyJ m 273936.0 0.0   1   0.0 0.0 273936.0, 273936.0 -0.4
BXD40/TyJ m 162253.0 0.0   1   0.0 0.0 162253.0, 162253.0 -0.65
BXD42/TyJ m 374669.0 0.0   1   0.0 0.0 374669.0, 374669.0 -0.18
BXD5/TyJ m 519230.0 0.0   1   0.0 0.0 519230.0, 519230.0 0.13
BXD6/TyJ m 614494.0 0.0   1   0.0 0.0 614494.0, 614494.0 0.34
BXD8/TyJ m 120709.0 0.0   1   0.0 0.0 120709.0, 120709.0 -0.74
BXD9/TyJ m 435853.0 0.0   1   0.0 0.0 435853.0, 435853.0 -0.05
BXH10/TyJ m 271382.0 0.0   1   0.0 0.0 271382.0, 271382.0 -0.41
BXH19/TyJ m 1989463.0 0.0   1   0.0 0.0 1989463.0, 1989463.0 3.33
BXH20/KccJ m 672166.0 0.0   1   0.0 0.0 672166.0, 672166.0 0.46
BXH22/KccJ m 257583.0 0.0   1   0.0 0.0 257583.0, 257583.0 -0.44
BXH2/TyJ m 435332.0 0.0   1   0.0 0.0 435332.0, 435332.0 -0.05
BXH4/TyJ m 417409.0 30663.0   2   21682.0 0.0735 395727.0, 439092.0 -0.09
BXH6/TyJ m 510917.0 0.0   1   0.0 0.0 510917.0, 510917.0 0.11
BXH7/TyJ m 1017503.0 0.0   1   0.0 0.0 1017503.0, 1017503.0 1.21
BXH8/TyJ m 529596.0 0.0   1   0.0 0.0 529596.0, 529596.0 0.15
BXH9/TyJ m 224722.0 0.0   1   0.0 0.0 224722.0, 224722.0 -0.51
C3H/HeJ m 348773.0 126807.0   2   89666.0 0.364 259107.0, 438439.0 -0.24
C57BL/6J m 226298.0 66544.0   4 33272.0 0.294 149009.0, 302013.0 -0.51
C57L/J m 144937.0 0.0   1   0.0 0.0 144937.0, 144937.0 -0.68
C58/J m 1658129.0 0.0   1   0.0 0.0 1658129.0, 1658129.0 2.61
CAST/EiJ m 1097559.0 0.0   1   0.0 0.0 1097559.0, 1097559.0 1.39
CBA/J m 181482.0 0.0   1   0.0 0.0 181482.0, 181482.0 -0.6
CE/J m 271382.0 0.0   1   0.0 0.0 271382.0, 271382.0 -0.41
CXB11/HiAJ m 174595.0 0.0   1   0.0 0.0 174595.0, 174595.0 -0.62
CXB12/HiAJ m 158126.0 0.0   1   0.0 0.0 158126.0, 158126.0 -0.66
CXB13/HiAJ m 620973.0 524898.0   3 303050.0 0.845 246909.0, 1221012.0 0.35
CXB1/ByJ m 576278.0 557547.0   3 321900.0 0.967 194678.0, 1216127.0 0.25
CXB2/ByJ m 155390.0 0.0   1   0.0 0.0 155390.0, 155390.0 -0.66
CXB3/ByJ m 350424.0 78511.0   2   55516.0 0.224 294908.0, 405940.0 -0.24
CXB4/ByJ m 206667.0 101957.0   2   72095.0 0.493 134572.0, 278761.0 -0.55
CXB6/ByJ m 140180.0 129079.0   2   91273.0 0.921 48907.0, 231452.0 -0.69
CXB7/ByJ m 181951.0 4883.0   2   3453.0 0.0268 178498.0, 185404.0 -0.6
CXB8/HiAJ m 480381.0 343797.0   3 198491.0 0.716 131838.0, 819227.0 0.05
CXB9/HiAJ m 121472.0 116883.0   2   82649.0 0.962 38822.0, 204121.0 -0.73
DBA/2J m 399986.0 236904.0   4 118452.0 0.592 146428.0, 693316.0 -0.13
FVB/NJ m 488281.0 0.0   1   0.0 0.0 488281.0, 488281.0 0.06
I/LnJ m 532851.0 0.0   1   0.0 0.0 532851.0, 532851.0 0.16
KK/HlJ m 356442.0 0.0   1   0.0 0.0 356442.0, 356442.0 -0.22
LG/J m 1108793.0 0.0   1   0.0 0.0 1108793.0, 1108793.0 1.41
LP/J m 620546.0 0.0   1   0.0 0.0 620546.0, 620546.0 0.35
MA/MyJ m 148050.0 0.0   1   0.0 0.0 148050.0, 148050.0 -0.68
NOD/ShiLtJ m 230868.0 0.0   1   0.0 0.0 230868.0, 230868.0 -0.5
NON/ShiLtJ m 1863276.0 0.0   1   0.0 0.0 1863276.0, 1863276.0 3.05
NZW/LacJ m 205980.0 0.0   1   0.0 0.0 205980.0, 205980.0 -0.55
PL/J m 373152.0 0.0   1   0.0 0.0 373152.0, 373152.0 -0.19
RIIIS/J m 105393.0 0.0   1   0.0 0.0 105393.0, 105393.0 -0.77
SEA/GnJ m 254354.0 0.0   1   0.0 0.0 254354.0, 254354.0 -0.45
SJL/J m 929155.0 0.0   1   0.0 0.0 929155.0, 929155.0 1.02
SM/J m 855869.0 0.0   1   0.0 0.0 855869.0, 855869.0 0.86
SWR/J m 327229.0 0.0   1   0.0 0.0 327229.0, 327229.0 -0.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 154272.95 217619.4799 601596.1974 0.0
AXB19b/PgnJ m 1595482.1 217619.4799 2042805.3474 1148158.8526
BALB/cJ m 216063.7 177685.5613 581301.602 0.0
BXA16/PgnJ m 198500.4 217619.4799 645823.6474 0.0
BXD19/TyJ m 255127.4 217619.4799 702450.6474 0.0
BXD28/TyJ m 213700.2 217619.4799 661023.4474 0.0
BXH4/TyJ m 417409.45 217619.4799 864732.6974 0.0
C3H/HeJ m 348773.05 217619.4799 796096.2974 0.0
C57BL/6J m 226297.6 153880.21 542602.9016 0.0
CXB13/HiAJ m 620972.6667 177685.5613 986210.5687 255734.7646
CXB1/ByJ m 576278.3 177685.5613 941516.202 211040.398
CXB3/ByJ m 350423.85 217619.4799 797747.0974 0.0
CXB4/ByJ m 206666.55 217619.4799 653989.7974 0.0
CXB6/ByJ m 140179.75 217619.4799 587502.9974 0.0
CXB7/ByJ m 181951.0 217619.4799 629274.2474 0.0
CXB8/HiAJ m 480381.4333 177685.5613 845619.3354 115143.5313
CXB9/HiAJ m 121471.55 217619.4799 568794.7974 0.0
DBA/2J m 399986.425 153880.21 716291.7266 83681.1234




  GWAS USING LINEAR MIXED MODELS