Phenotype measure:   HMDPpheno8   malonate

ID, description, units MPD:50376   malonate   liver malonate (propanedioate) (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver malonate (propanedioate) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means159829   None
Median of the strain means17464   None
SD of the strain means± 363562
Coefficient of variation (CV)2.27
Min–max range of strain means7687   –   1666027   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 2842152173149.15 135340579673.769 6.316 < 0.0001
Residuals 34 728557859724.133 21428172344.8274


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 19635.0 0.0   1   0.0 0.0 19635.0, 19635.0 -0.39
A/J m 25633.0 6012.0   2   4251.0 0.235 21382.0, 29884.0 -0.37
AKR/J m 16263.0 0.0   1   0.0 0.0 16263.0, 16263.0 -0.39
AXB10/PgnJ m 16862.0 0.0   1   0.0 0.0 16862.0, 16862.0 -0.39
AXB12/PgnJ m 16499.0 0.0   1   0.0 0.0 16499.0, 16499.0 -0.39
AXB13/PgnJ m 27518.0 0.0   1   0.0 0.0 27518.0, 27518.0 -0.36
AXB15/PgnJ m 26744.0 0.0   1   0.0 0.0 26744.0, 26744.0 -0.37
AXB19a/PgnJ m 21091.0 0.0   1   0.0 0.0 21091.0, 21091.0 -0.38
AXB19b/PgnJ m 18154.0 5495.0   2   3885.0 0.303 14269.0, 22040.0 -0.39
AXB19/PgnJ m 13724.0 0.0   1   0.0 0.0 13724.0, 13724.0 -0.4
AXB1/PgnJ m 18362.0 0.0   1   0.0 0.0 18362.0, 18362.0 -0.39
AXB23/PgnJ m 14532.0 0.0   1   0.0 0.0 14532.0, 14532.0 -0.4
AXB24/PgnJ m 16859.0 5673.0   2   4012.0 0.337 12848.0, 20871.0 -0.39
AXB2/PgnJ m 23000.0 0.0   1   0.0 0.0 23000.0, 23000.0 -0.38
AXB4/PgnJ m 22737.0 0.0   1   0.0 0.0 22737.0, 22737.0 -0.38
AXB5/PgnJ m 13175.0 0.0   1   0.0 0.0 13175.0, 13175.0 -0.4
AXB6/PgnJ m 12414.0 0.0   1   0.0 0.0 12414.0, 12414.0 -0.41
AXB8/PgnJ m 17175.0 0.0   1   0.0 0.0 17175.0, 17175.0 -0.39
BALB/cJ m 15533.0 5118.0   3 2955.0 0.329 11395.0, 21256.0 -0.4
BTBR T+ Itpr3tf/J m 16272.0 0.0   1   0.0 0.0 16272.0, 16272.0 -0.39
BUB/BnJ m 17188.0 0.0   1   0.0 0.0 17188.0, 17188.0 -0.39
BXA11/PgnJ m 16958.0 0.0   1   0.0 0.0 16958.0, 16958.0 -0.39
BXA12/PgnJ m 32385.0 0.0   1   0.0 0.0 32385.0, 32385.0 -0.35
BXA13/PgnJ m 22274.0 0.0   1   0.0 0.0 22274.0, 22274.0 -0.38
BXA14/PgnJ m 7932.0 0.0   1   0.0 0.0 7932.0, 7932.0 -0.42
BXA16/PgnJ m 358434.0 492363.0   2   348154.0 1.37 10281.0, 706588.0 0.55
BXA1/PgnJ m 11609.0 0.0   1   0.0 0.0 11609.0, 11609.0 -0.41
BXA24/PgnJ m 17486.0 0.0   1   0.0 0.0 17486.0, 17486.0 -0.39
BXA25/PgnJ m 26657.0 0.0   1   0.0 0.0 26657.0, 26657.0 -0.37
BXA26/PgnJ m 7687.0 0.0   1   0.0 0.0 7687.0, 7687.0 -0.42
BXA2/PgnJ m 13060.0 0.0   1   0.0 0.0 13060.0, 13060.0 -0.4
BXA4/PgnJ m 61777.0 0.0   1   0.0 0.0 61777.0, 61777.0 -0.27
BXA7/PgnJ m 12766.0 0.0   1   0.0 0.0 12766.0, 12766.0 -0.4
BXA8/PgnJ m 18615.0 0.0   1   0.0 0.0 18615.0, 18615.0 -0.39
BXD11/TyJ m 297391.0 0.0   1   0.0 0.0 297391.0, 297391.0 0.38
BXD12/TyJ m 17106.0 0.0   1   0.0 0.0 17106.0, 17106.0 -0.39
BXD13/TyJ m 18695.0 0.0   1   0.0 0.0 18695.0, 18695.0 -0.39
BXD14/TyJ m 18393.0 0.0   1   0.0 0.0 18393.0, 18393.0 -0.39
BXD15/TyJ m 439815.0 0.0   1   0.0 0.0 439815.0, 439815.0 0.77
BXD18/TyJ m 29365.0 0.0   1   0.0 0.0 29365.0, 29365.0 -0.36
BXD19/TyJ m 412104.0 560713.0   2   396484.0 1.36 15620.0, 808588.0 0.69
BXD1/TyJ m 1589354.0 0.0   1   0.0 0.0 1589354.0, 1589354.0 3.93
BXD20/TyJ m 1666027.0 0.0   1   0.0 0.0 1666027.0, 1666027.0 4.14
BXD21/TyJ m 518507.0 0.0   1   0.0 0.0 518507.0, 518507.0 0.99
BXD22/TyJ m 364473.0 0.0   1   0.0 0.0 364473.0, 364473.0 0.56
BXD24/TyJ m 548531.0 0.0   1   0.0 0.0 548531.0, 548531.0 1.07
BXD24/TyJ-Cep290rd16/J m 515224.0 0.0   1   0.0 0.0 515224.0, 515224.0 0.98
BXD28/TyJ m 16386.0 441.0   2   312.0 0.0269 16074.0, 16697.0 -0.39
BXD29-Tlr4lps-2J/J m 986608.0 0.0   1   0.0 0.0 986608.0, 986608.0 2.27
BXD2/TyJ m 14346.0 0.0   1   0.0 0.0 14346.0, 14346.0 -0.4
BXD32/TyJ m 25655.0 0.0   1   0.0 0.0 25655.0, 25655.0 -0.37
BXD33/TyJ m 458026.0 0.0   1   0.0 0.0 458026.0, 458026.0 0.82
BXD34/TyJ m 102356.0 0.0   1   0.0 0.0 102356.0, 102356.0 -0.16
BXD36/TyJ m 14916.0 0.0   1   0.0 0.0 14916.0, 14916.0 -0.4
BXD38/TyJ m 1072342.0 0.0   1   0.0 0.0 1072342.0, 1072342.0 2.51
BXD39/TyJ m 915222.0 0.0   1   0.0 0.0 915222.0, 915222.0 2.08
BXD40/TyJ m 16008.0 0.0   1   0.0 0.0 16008.0, 16008.0 -0.4
BXD42/TyJ m 1629813.0 0.0   1   0.0 0.0 1629813.0, 1629813.0 4.04
BXD5/TyJ m 159893.0 0.0   1   0.0 0.0 159893.0, 159893.0 0.0
BXD6/TyJ m 17292.0 0.0   1   0.0 0.0 17292.0, 17292.0 -0.39
BXD8/TyJ m 1179920.0 0.0   1   0.0 0.0 1179920.0, 1179920.0 2.81
BXD9/TyJ m 15558.0 0.0   1   0.0 0.0 15558.0, 15558.0 -0.4
BXH10/TyJ m 17442.0 0.0   1   0.0 0.0 17442.0, 17442.0 -0.39
BXH19/TyJ m 26549.0 0.0   1   0.0 0.0 26549.0, 26549.0 -0.37
BXH20/KccJ m 16013.0 0.0   1   0.0 0.0 16013.0, 16013.0 -0.4
BXH22/KccJ m 14546.0 0.0   1   0.0 0.0 14546.0, 14546.0 -0.4
BXH2/TyJ m 16316.0 0.0   1   0.0 0.0 16316.0, 16316.0 -0.39
BXH4/TyJ m 14336.0 1967.0   2   1391.0 0.137 12945.0, 15726.0 -0.4
BXH6/TyJ m 12378.0 0.0   1   0.0 0.0 12378.0, 12378.0 -0.41
BXH7/TyJ m 21069.0 0.0   1   0.0 0.0 21069.0, 21069.0 -0.38
BXH8/TyJ m 16008.0 0.0   1   0.0 0.0 16008.0, 16008.0 -0.4
BXH9/TyJ m 21374.0 0.0   1   0.0 0.0 21374.0, 21374.0 -0.38
C3H/HeJ m 19368.0 4688.0   2   3315.0 0.242 16053.0, 22682.0 -0.39
C57BL/6J m 14604.0 1906.0   5 852.0 0.131 12478.0, 16643.0 -0.4
C57L/J m 23480.0 0.0   1   0.0 0.0 23480.0, 23480.0 -0.38
C58/J m 11026.0 0.0   1   0.0 0.0 11026.0, 11026.0 -0.41
CAST/EiJ m 14536.0 0.0   1   0.0 0.0 14536.0, 14536.0 -0.4
CBA/J m 16454.0 0.0   1   0.0 0.0 16454.0, 16454.0 -0.39
CE/J m 18101.0 0.0   1   0.0 0.0 18101.0, 18101.0 -0.39
CXB11/HiAJ m 15400.0 2788.0   2   1971.0 0.181 13429.0, 17372.0 -0.4
CXB12/HiAJ m 13471.0 562.0   2   397.0 0.0417 13074.0, 13868.0 -0.4
CXB13/HiAJ m 14016.0 1768.0   3 1021.0 0.126 12015.0, 15365.0 -0.4
CXB1/ByJ m 12964.0 1720.0   3 993.0 0.133 11090.0, 14471.0 -0.4
CXB2/ByJ m 12977.0 2068.0   3 1194.0 0.159 10869.0, 15003.0 -0.4
CXB3/ByJ m 16178.0 3781.0   2   2674.0 0.234 13504.0, 18851.0 -0.4
CXB4/ByJ m 13411.0 3531.0   2   2496.0 0.263 10915.0, 15908.0 -0.4
CXB6/ByJ m 16880.0 2181.0   3 1259.0 0.129 15421.0, 19387.0 -0.39
CXB7/ByJ m 13395.0 3711.0   2   2624.0 0.277 10771.0, 16019.0 -0.4
CXB8/HiAJ m 10776.0 2507.0   3 1447.0 0.233 9201.0, 13667.0 -0.41
CXB9/HiAJ m 12779.0 2970.0   3 1715.0 0.232 9750.0, 15687.0 -0.4
DBA/2J m 836131.0 239051.0   4 119526.0 0.286 644354.0, 1178196.0 1.86
FVB/NJ m 22545.0 0.0   1   0.0 0.0 22545.0, 22545.0 -0.38
I/LnJ m 16808.0 0.0   1   0.0 0.0 16808.0, 16808.0 -0.39
KK/HlJ m 29184.0 0.0   1   0.0 0.0 29184.0, 29184.0 -0.36
LG/J m 15309.0 0.0   1   0.0 0.0 15309.0, 15309.0 -0.4
LP/J m 13343.0 0.0   1   0.0 0.0 13343.0, 13343.0 -0.4
MA/MyJ m 25409.0 0.0   1   0.0 0.0 25409.0, 25409.0 -0.37
NOD/ShiLtJ m 25440.0 0.0   1   0.0 0.0 25440.0, 25440.0 -0.37
NON/ShiLtJ m 24547.0 0.0   1   0.0 0.0 24547.0, 24547.0 -0.37
NZW/LacJ m 13660.0 0.0   1   0.0 0.0 13660.0, 13660.0 -0.4
PL/J m 20500.0 0.0   1   0.0 0.0 20500.0, 20500.0 -0.38
RIIIS/J m 21480.0 0.0   1   0.0 0.0 21480.0, 21480.0 -0.38
SEA/GnJ m 16330.0 0.0   1   0.0 0.0 16330.0, 16330.0 -0.39
SJL/J m 23198.0 0.0   1   0.0 0.0 23198.0, 23198.0 -0.38
SM/J m 1322671.0 0.0   1   0.0 0.0 1322671.0, 1322671.0 3.2
SWR/J m 13112.0 0.0   1   0.0 0.0 13112.0, 13112.0 -0.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 25632.9 103508.87 235988.2328 0.0
AXB19b/PgnJ m 18154.3 103508.87 228509.6328 0.0
AXB24/PgnJ m 16859.35 103508.87 227214.6828 0.0
BALB/cJ m 15532.8667 84514.6385 187287.2766 0.0
BXA16/PgnJ m 358434.4 103508.87 568789.7328 148079.0672
BXD19/TyJ m 412104.3 103508.87 622459.6328 201748.9672
BXD28/TyJ m 16385.8 103508.87 226741.1328 0.0
BXH4/TyJ m 14335.95 103508.87 224691.2828 0.0
C3H/HeJ m 19367.65 103508.87 229722.9828 0.0
C57BL/6J m 14604.38 65464.7575 147644.7739 0.0
CXB11/HiAJ m 15400.3 103508.87 225755.6328 0.0
CXB12/HiAJ m 13471.05 103508.87 223826.3828 0.0
CXB13/HiAJ m 14016.1333 84514.6385 185770.5433 0.0
CXB1/ByJ m 12963.9667 84514.6385 184718.3766 0.0
CXB2/ByJ m 12977.3667 84514.6385 184731.7766 0.0
CXB3/ByJ m 16177.75 103508.87 226533.0828 0.0
CXB4/ByJ m 13411.4 103508.87 223766.7328 0.0
CXB6/ByJ m 16880.0667 84514.6385 188634.4766 0.0
CXB7/ByJ m 13395.1 103508.87 223750.4328 0.0
CXB8/HiAJ m 10776.1 84514.6385 182530.51 0.0
CXB9/HiAJ m 12779.1 84514.6385 184533.51 0.0
DBA/2J m 836130.875 73191.8239 984874.5573 687387.1927




  GWAS USING LINEAR MIXED MODELS