Phenotype measure:   HMDPpheno8   propanediol

ID, description, units MPD:50352   propanediol   liver 1,2-propanediol (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver 1,2-propanediol (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means3062134   None
Median of the strain means1090392   None
SD of the strain means± 8004144
Coefficient of variation (CV)2.61
Min–max range of strain means145436   –   74725872   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 858758264891870.0 42937913244593.5 1.7429 0.0765
Residuals 33 812990076628807.0 24636062928145.7


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 973143.0 493098.0   2   348673.0 0.507 624470.0, 1321816.0 -0.26
AKR/J m 2331790.0 0.0   1   0.0 0.0 2331790.0, 2331790.0 -0.09
AXB10/PgnJ m 1332809.0 0.0   1   0.0 0.0 1332809.0, 1332809.0 -0.22
AXB12/PgnJ m 1262294.0 0.0   1   0.0 0.0 1262294.0, 1262294.0 -0.22
AXB13/PgnJ m 1363307.0 0.0   1   0.0 0.0 1363307.0, 1363307.0 -0.21
AXB15/PgnJ m 886301.0 0.0   1   0.0 0.0 886301.0, 886301.0 -0.27
AXB19a/PgnJ m 1812081.0 0.0   1   0.0 0.0 1812081.0, 1812081.0 -0.16
AXB19b/PgnJ m 1444575.0 166998.0   2   118086.0 0.116 1326490.0, 1562661.0 -0.2
AXB19/PgnJ m 1748214.0 0.0   1   0.0 0.0 1748214.0, 1748214.0 -0.16
AXB1/PgnJ m 2543813.0 0.0   1   0.0 0.0 2543813.0, 2543813.0 -0.06
AXB23/PgnJ m 204941.0 0.0   1   0.0 0.0 204941.0, 204941.0 -0.36
AXB24/PgnJ m 21548111.0 27519795.0   2   19459433.0 1.28 2088677.0, 41007544.0 2.31
AXB2/PgnJ m 1275922.0 0.0   1   0.0 0.0 1275922.0, 1275922.0 -0.22
AXB4/PgnJ m 2243610.0 0.0   1   0.0 0.0 2243610.0, 2243610.0 -0.1
AXB5/PgnJ m 832260.0 0.0   1   0.0 0.0 832260.0, 832260.0 -0.28
AXB6/PgnJ m 677700.0 0.0   1   0.0 0.0 677700.0, 677700.0 -0.3
AXB8/PgnJ m 865970.0 0.0   1   0.0 0.0 865970.0, 865970.0 -0.27
BALB/cJ m 3902671.0 4454299.0   3 2571691.0 1.14 1158220.0, 9042093.0 0.11
BTBR T+ Itpr3tf/J m 74725872.0 0.0   1   0.0 0.0 74725872.0, 74725872.0 8.95
BUB/BnJ m 1199597.0 0.0   1   0.0 0.0 1199597.0, 1199597.0 -0.23
BXA12/PgnJ m 2019906.0 0.0   1   0.0 0.0 2019906.0, 2019906.0 -0.13
BXA13/PgnJ m 1424043.0 0.0   1   0.0 0.0 1424043.0, 1424043.0 -0.2
BXA14/PgnJ m 9961089.0 0.0   1   0.0 0.0 9961089.0, 9961089.0 0.86
BXA16/PgnJ m 2153278.0 2340720.0   2   1655139.0 1.09 498139.0, 3808417.0 -0.11
BXA1/PgnJ m 2073308.0 0.0   1   0.0 0.0 2073308.0, 2073308.0 -0.12
BXA24/PgnJ m 2042601.0 0.0   1   0.0 0.0 2042601.0, 2042601.0 -0.13
BXA25/PgnJ m 3036072.0 0.0   1   0.0 0.0 3036072.0, 3036072.0 0.0
BXA26/PgnJ m 352064.0 0.0   1   0.0 0.0 352064.0, 352064.0 -0.34
BXA2/PgnJ m 613260.0 0.0   1   0.0 0.0 613260.0, 613260.0 -0.31
BXA4/PgnJ m 543938.0 0.0   1   0.0 0.0 543938.0, 543938.0 -0.31
BXA7/PgnJ m 884660.0 0.0   1   0.0 0.0 884660.0, 884660.0 -0.27
BXA8/PgnJ m 189339.0 0.0   1   0.0 0.0 189339.0, 189339.0 -0.36
BXD11/TyJ m 734720.0 0.0   1   0.0 0.0 734720.0, 734720.0 -0.29
BXD12/TyJ m 770220.0 0.0   1   0.0 0.0 770220.0, 770220.0 -0.29
BXD13/TyJ m 688634.0 0.0   1   0.0 0.0 688634.0, 688634.0 -0.3
BXD14/TyJ m 848018.0 0.0   1   0.0 0.0 848018.0, 848018.0 -0.28
BXD15/TyJ m 2501004.0 0.0   1   0.0 0.0 2501004.0, 2501004.0 -0.07
BXD18/TyJ m 1584374.0 0.0   1   0.0 0.0 1584374.0, 1584374.0 -0.18
BXD19/TyJ m 209710.0 65913.0   2   46607.0 0.314 163102.0, 256317.0 -0.36
BXD1/TyJ m 373452.0 0.0   1   0.0 0.0 373452.0, 373452.0 -0.34
BXD20/TyJ m 692728.0 0.0   1   0.0 0.0 692728.0, 692728.0 -0.3
BXD21/TyJ m 238466.0 0.0   1   0.0 0.0 238466.0, 238466.0 -0.35
BXD22/TyJ m 854420.0 0.0   1   0.0 0.0 854420.0, 854420.0 -0.28
BXD24/TyJ m 3092061.0 0.0   1   0.0 0.0 3092061.0, 3092061.0 0.0
BXD24/TyJ-Cep290rd16/J m 5625318.0 0.0   1   0.0 0.0 5625318.0, 5625318.0 0.32
BXD28/TyJ m 762070.0 285547.0   2   201912.0 0.375 560158.0, 963982.0 -0.29
BXD29-Tlr4lps-2J/J m 4032902.0 0.0   1   0.0 0.0 4032902.0, 4032902.0 0.12
BXD2/TyJ m 8894905.0 0.0   1   0.0 0.0 8894905.0, 8894905.0 0.73
BXD32/TyJ m 489825.0 0.0   1   0.0 0.0 489825.0, 489825.0 -0.32
BXD33/TyJ m 4037314.0 0.0   1   0.0 0.0 4037314.0, 4037314.0 0.12
BXD34/TyJ m 210244.0 0.0   1   0.0 0.0 210244.0, 210244.0 -0.36
BXD36/TyJ m 2733582.0 0.0   1   0.0 0.0 2733582.0, 2733582.0 -0.04
BXD38/TyJ m 375527.0 0.0   1   0.0 0.0 375527.0, 375527.0 -0.34
BXD39/TyJ m 695774.0 0.0   1   0.0 0.0 695774.0, 695774.0 -0.3
BXD40/TyJ m 2602901.0 0.0   1   0.0 0.0 2602901.0, 2602901.0 -0.06
BXD42/TyJ m 1718009.0 0.0   1   0.0 0.0 1718009.0, 1718009.0 -0.17
BXD5/TyJ m 4061730.0 0.0   1   0.0 0.0 4061730.0, 4061730.0 0.12
BXD6/TyJ m 981188.0 0.0   1   0.0 0.0 981188.0, 981188.0 -0.26
BXD8/TyJ m 3209903.0 0.0   1   0.0 0.0 3209903.0, 3209903.0 0.02
BXD9/TyJ m 351303.0 0.0   1   0.0 0.0 351303.0, 351303.0 -0.34
BXH10/TyJ m 350573.0 0.0   1   0.0 0.0 350573.0, 350573.0 -0.34
BXH19/TyJ m 3290357.0 0.0   1   0.0 0.0 3290357.0, 3290357.0 0.03
BXH20/KccJ m 809094.0 0.0   1   0.0 0.0 809094.0, 809094.0 -0.28
BXH22/KccJ m 670923.0 0.0   1   0.0 0.0 670923.0, 670923.0 -0.3
BXH2/TyJ m 536279.0 0.0   1   0.0 0.0 536279.0, 536279.0 -0.32
BXH4/TyJ m 2742878.0 1805859.0   2   1276935.0 0.658 1465942.0, 4019813.0 -0.04
BXH6/TyJ m 1416960.0 0.0   1   0.0 0.0 1416960.0, 1416960.0 -0.21
BXH7/TyJ m 1212342.0 0.0   1   0.0 0.0 1212342.0, 1212342.0 -0.23
BXH8/TyJ m 8000522.0 0.0   1   0.0 0.0 8000522.0, 8000522.0 0.62
BXH9/TyJ m 7029076.0 0.0   1   0.0 0.0 7029076.0, 7029076.0 0.5
C3H/HeJ m 1940535.0 1421975.0   2   1005488.0 0.733 935047.0, 2946024.0 -0.14
C57BL/6J m 458080.0 338535.0   5 151397.0 0.739 67247.0, 995015.0 -0.33
C57L/J m 145436.0 0.0   1   0.0 0.0 145436.0, 145436.0 -0.36
C58/J m 556099.0 0.0   1   0.0 0.0 556099.0, 556099.0 -0.31
CAST/EiJ m 7368032.0 0.0   1   0.0 0.0 7368032.0, 7368032.0 0.54
CBA/J m 759421.0 0.0   1   0.0 0.0 759421.0, 759421.0 -0.29
CE/J m 925787.0 0.0   1   0.0 0.0 925787.0, 925787.0 -0.27
CXB11/HiAJ m 182804.0 0.0   1   0.0 0.0 182804.0, 182804.0 -0.36
CXB12/HiAJ m 321258.0 73328.0   2   51851.0 0.228 269407.0, 373108.0 -0.34
CXB13/HiAJ m 804815.0 202080.0   3 116671.0 0.251 572517.0, 940061.0 -0.28
CXB1/ByJ m 765580.0 1113448.0   3 642850.0 1.45 77545.0, 2050194.0 -0.29
CXB2/ByJ m 447014.0 224216.0   3 129451.0 0.502 224585.0, 672975.0 -0.33
CXB3/ByJ m 2066270.0 600559.0   2   424659.0 0.291 1641611.0, 2490930.0 -0.12
CXB4/ByJ m 952195.0 232835.0   2   164639.0 0.245 787556.0, 1116834.0 -0.26
CXB6/ByJ m 183345.0 145627.0   3 84078.0 0.794 59585.0, 343814.0 -0.36
CXB7/ByJ m 296372.0 329959.0   2   233316.0 1.11 63056.0, 529688.0 -0.35
CXB8/HiAJ m 380826.0 478852.0   3 276465.0 1.26 78512.0, 932924.0 -0.33
CXB9/HiAJ m 451319.0 186836.0   3 107870.0 0.414 295449.0, 658428.0 -0.33
DBA/2J m 784064.0 458350.0   4 229175.0 0.585 301398.0, 1276130.0 -0.28
FVB/NJ m 5977134.0 0.0   1   0.0 0.0 5977134.0, 5977134.0 0.36
I/LnJ m 784471.0 0.0   1   0.0 0.0 784471.0, 784471.0 -0.28
KK/HlJ m 7996603.0 0.0   1   0.0 0.0 7996603.0, 7996603.0 0.62
LG/J m 2314358.0 0.0   1   0.0 0.0 2314358.0, 2314358.0 -0.09
LP/J m 930801.0 0.0   1   0.0 0.0 930801.0, 930801.0 -0.27
MA/MyJ m 468557.0 0.0   1   0.0 0.0 468557.0, 468557.0 -0.32
NOD/ShiLtJ m 12772406.0 0.0   1   0.0 0.0 12772406.0, 12772406.0 1.21
NON/ShiLtJ m 207235.0 0.0   1   0.0 0.0 207235.0, 207235.0 -0.36
NZW/LacJ m 3237121.0 0.0   1   0.0 0.0 3237121.0, 3237121.0 0.02
PL/J m 24763786.0 0.0   1   0.0 0.0 24763786.0, 24763786.0 2.71
RIIIS/J m 2533412.0 0.0   1   0.0 0.0 2533412.0, 2533412.0 -0.07
SEA/GnJ m 299627.0 0.0   1   0.0 0.0 299627.0, 299627.0 -0.35
SJL/J m 2376230.0 0.0   1   0.0 0.0 2376230.0, 2376230.0 -0.09
SM/J m 4237660.0 0.0   1   0.0 0.0 4237660.0, 4237660.0 0.15
SWR/J m 1875470.0 0.0   1   0.0 0.0 1875470.0, 1875470.0 -0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 973143.35 3509705.3244 8113692.522 0.0
AXB19b/PgnJ m 1444575.15 3509705.3244 8585124.322 0.0
AXB24/PgnJ m 21548110.55 3509705.3244 28688659.722 14407561.378
BALB/cJ m 3902670.6 2865662.3974 9732904.5849 0.0
BXA16/PgnJ m 2153278.25 3509705.3244 9293827.422 0.0
BXD19/TyJ m 209709.6 3509705.3244 7350258.772 0.0
BXD28/TyJ m 762070.0 3509705.3244 7902619.172 0.0
BXH4/TyJ m 2742877.65 3509705.3244 9883426.822 0.0
C3H/HeJ m 1940535.4 3509705.3244 9081084.572 0.0
C57BL/6J m 458080.48 2219732.5482 4974160.3056 0.0
CXB12/HiAJ m 321257.8 3509705.3244 7461806.972 0.0
CXB13/HiAJ m 804815.0333 2865662.3974 6635049.0182 0.0
CXB1/ByJ m 765579.5667 2865662.3974 6595813.5516 0.0
CXB2/ByJ m 447013.7 2865662.3974 6277247.6849 0.0
CXB3/ByJ m 2066270.05 3509705.3244 9206819.222 0.0
CXB4/ByJ m 952194.7 3509705.3244 8092743.872 0.0
CXB6/ByJ m 183344.7667 2865662.3974 6013578.7516 0.0
CXB7/ByJ m 296372.2 3509705.3244 7436921.372 0.0
CXB8/HiAJ m 380826.0333 2865662.3974 6211060.0182 0.0
CXB9/HiAJ m 451319.4667 2865662.3974 6281553.4516 0.0
DBA/2J m 784064.0 2481736.4348 5833194.7409 0.0




  GWAS USING LINEAR MIXED MODELS