Phenotype measure:   HMDPpheno8   ursodeoxycholate

ID, description, units MPD:50310   ursodeoxycholate   ursodeoxycholate (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - ursodeoxycholate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means115879   None
Median of the strain means97320   None
SD of the strain means± 66778
Coefficient of variation (CV)0.576
Min–max range of strain means17672   –   369294   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 226456091561.25 10783623407.6786 3.1605 0.0017
Residuals 32 109182601855.122 3411956307.9726


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 42207.0 0.0   1   0.0 0.0 42207.0, 42207.0 -1.1
A/J m 126088.0 86595.0   2   61232.0 0.687 64856.0, 187320.0 0.15
AKR/J m 155679.0 0.0   1   0.0 0.0 155679.0, 155679.0 0.6
AXB10/PgnJ m 65191.0 0.0   1   0.0 0.0 65191.0, 65191.0 -0.76
AXB12/PgnJ m 88197.0 0.0   1   0.0 0.0 88197.0, 88197.0 -0.41
AXB13/PgnJ m 124090.0 0.0   1   0.0 0.0 124090.0, 124090.0 0.12
AXB15/PgnJ m 30690.0 0.0   1   0.0 0.0 30690.0, 30690.0 -1.28
AXB19a/PgnJ m 115400.0 0.0   1   0.0 0.0 115400.0, 115400.0 -0.01
AXB19b/PgnJ m 151756.0 62198.0   2   43980.0 0.41 107776.0, 195737.0 0.54
AXB19/PgnJ m 129822.0 0.0   1   0.0 0.0 129822.0, 129822.0 0.21
AXB1/PgnJ m 63226.0 0.0   1   0.0 0.0 63226.0, 63226.0 -0.79
AXB23/PgnJ m 86865.0 0.0   1   0.0 0.0 86865.0, 86865.0 -0.43
AXB24/PgnJ m 68289.0 19065.0   2   13481.0 0.279 54808.0, 81770.0 -0.71
AXB2/PgnJ m 129940.0 0.0   1   0.0 0.0 129940.0, 129940.0 0.21
AXB4/PgnJ m 74410.0 0.0   1   0.0 0.0 74410.0, 74410.0 -0.62
AXB5/PgnJ m 112584.0 0.0   1   0.0 0.0 112584.0, 112584.0 -0.05
AXB6/PgnJ m 88073.0 0.0   1   0.0 0.0 88073.0, 88073.0 -0.42
AXB8/PgnJ m 169569.0 0.0   1   0.0 0.0 169569.0, 169569.0 0.8
BALB/cJ m 330500.0 105430.0   3 60870.0 0.319 214258.0, 419948.0 3.21
BTBR T+ Itpr3tf/J m 102948.0 0.0   1   0.0 0.0 102948.0, 102948.0 -0.19
BUB/BnJ m 83974.0 0.0   1   0.0 0.0 83974.0, 83974.0 -0.48
BXA11/PgnJ m 121872.0 0.0   1   0.0 0.0 121872.0, 121872.0 0.09
BXA12/PgnJ m 52735.0 0.0   1   0.0 0.0 52735.0, 52735.0 -0.95
BXA13/PgnJ m 131765.0 0.0   1   0.0 0.0 131765.0, 131765.0 0.24
BXA14/PgnJ m 138905.0 0.0   1   0.0 0.0 138905.0, 138905.0 0.34
BXA16/PgnJ m 77868.0 66237.0   2   46837.0 0.851 31032.0, 124705.0 -0.57
BXA1/PgnJ m 44824.0 0.0   1   0.0 0.0 44824.0, 44824.0 -1.06
BXA24/PgnJ m 73430.0 0.0   1   0.0 0.0 73430.0, 73430.0 -0.64
BXA25/PgnJ m 103480.0 0.0   1   0.0 0.0 103480.0, 103480.0 -0.19
BXA26/PgnJ m 62828.0 0.0   1   0.0 0.0 62828.0, 62828.0 -0.79
BXA2/PgnJ m 77296.0 0.0   1   0.0 0.0 77296.0, 77296.0 -0.58
BXA4/PgnJ m 17672.0 0.0   1   0.0 0.0 17672.0, 17672.0 -1.47
BXA7/PgnJ m 109178.0 0.0   1   0.0 0.0 109178.0, 109178.0 -0.1
BXA8/PgnJ m 216644.0 0.0   1   0.0 0.0 216644.0, 216644.0 1.51
BXD11/TyJ m 282529.0 0.0   1   0.0 0.0 282529.0, 282529.0 2.5
BXD12/TyJ m 52300.0 0.0   1   0.0 0.0 52300.0, 52300.0 -0.95
BXD13/TyJ m 202909.0 0.0   1   0.0 0.0 202909.0, 202909.0 1.3
BXD14/TyJ m 104011.0 0.0   1   0.0 0.0 104011.0, 104011.0 -0.18
BXD15/TyJ m 62676.0 0.0   1   0.0 0.0 62676.0, 62676.0 -0.8
BXD18/TyJ m 47839.0 0.0   1   0.0 0.0 47839.0, 47839.0 -1.02
BXD19/TyJ m 208722.0 100042.0   2   70740.0 0.479 137982.0, 279463.0 1.39
BXD1/TyJ m 65255.0 0.0   1   0.0 0.0 65255.0, 65255.0 -0.76
BXD20/TyJ m 76129.0 0.0   1   0.0 0.0 76129.0, 76129.0 -0.6
BXD21/TyJ m 74696.0 0.0   1   0.0 0.0 74696.0, 74696.0 -0.62
BXD22/TyJ m 39009.0 0.0   1   0.0 0.0 39009.0, 39009.0 -1.15
BXD24/TyJ m 68549.0 0.0   1   0.0 0.0 68549.0, 68549.0 -0.71
BXD24/TyJ-Cep290rd16/J m 90845.0 0.0   1   0.0 0.0 90845.0, 90845.0 -0.37
BXD28/TyJ m 89617.0 20856.0   2   14747.0 0.233 74870.0, 104364.0 -0.39
BXD29-Tlr4lps-2J/J m 78836.0 0.0   1   0.0 0.0 78836.0, 78836.0 -0.55
BXD2/TyJ m 79296.0 0.0   1   0.0 0.0 79296.0, 79296.0 -0.55
BXD32/TyJ m 66714.0 0.0   1   0.0 0.0 66714.0, 66714.0 -0.74
BXD33/TyJ m 94300.0 0.0   1   0.0 0.0 94300.0, 94300.0 -0.32
BXD34/TyJ m 230284.0 0.0   1   0.0 0.0 230284.0, 230284.0 1.71
BXD36/TyJ m 138320.0 0.0   1   0.0 0.0 138320.0, 138320.0 0.34
BXD38/TyJ m 222089.0 0.0   1   0.0 0.0 222089.0, 222089.0 1.59
BXD39/TyJ m 78974.0 0.0   1   0.0 0.0 78974.0, 78974.0 -0.55
BXD40/TyJ m 50092.0 0.0   1   0.0 0.0 50092.0, 50092.0 -0.99
BXD42/TyJ m 44288.0 0.0   1   0.0 0.0 44288.0, 44288.0 -1.07
BXD5/TyJ m 103656.0 0.0   1   0.0 0.0 103656.0, 103656.0 -0.18
BXD6/TyJ m 94038.0 0.0   1   0.0 0.0 94038.0, 94038.0 -0.33
BXD8/TyJ m 58983.0 0.0   1   0.0 0.0 58983.0, 58983.0 -0.85
BXD9/TyJ m 155552.0 0.0   1   0.0 0.0 155552.0, 155552.0 0.59
BXH10/TyJ m 91591.0 0.0   1   0.0 0.0 91591.0, 91591.0 -0.36
BXH19/TyJ m 196972.0 0.0   1   0.0 0.0 196972.0, 196972.0 1.21
BXH20/KccJ m 75511.0 0.0   1   0.0 0.0 75511.0, 75511.0 -0.6
BXH22/KccJ m 63032.0 0.0   1   0.0 0.0 63032.0, 63032.0 -0.79
BXH2/TyJ m 103480.0 0.0   1   0.0 0.0 103480.0, 103480.0 -0.19
BXH4/TyJ m 96113.0 102532.0   2   72501.0 1.07 23611.0, 168614.0 -0.3
BXH6/TyJ m 158469.0 0.0   1   0.0 0.0 158469.0, 158469.0 0.64
BXH7/TyJ m 100886.0 0.0   1   0.0 0.0 100886.0, 100886.0 -0.22
BXH8/TyJ m 159262.0 0.0   1   0.0 0.0 159262.0, 159262.0 0.65
BXH9/TyJ m 369294.0 0.0   1   0.0 0.0 369294.0, 369294.0 3.79
C3H/HeJ m 215961.0 132619.0   2   93776.0 0.614 122185.0, 309737.0 1.5
C57BL/6J m 131140.0 46423.0   5 20761.0 0.354 91996.0, 207701.0 0.23
C57L/J m 21093.0 0.0   1   0.0 0.0 21093.0, 21093.0 -1.42
C58/J m 53126.0 0.0   1   0.0 0.0 53126.0, 53126.0 -0.94
CAST/EiJ m 101584.0 0.0   1   0.0 0.0 101584.0, 101584.0 -0.21
CBA/J m 108918.0 0.0   1   0.0 0.0 108918.0, 108918.0 -0.1
CE/J m 79752.0 0.0   1   0.0 0.0 79752.0, 79752.0 -0.54
CXB11/HiAJ m 62873.0 11412.0   2   8070.0 0.182 54804.0, 70943.0 -0.79
CXB12/HiAJ m 92652.0 41776.0   2   29540.0 0.451 63112.0, 122192.0 -0.35
CXB13/HiAJ m 138672.0 46278.0   2   32724.0 0.334 105949.0, 171396.0 0.34
CXB1/ByJ m 162543.0 20846.0   3 12036.0 0.128 146106.0, 185992.0 0.7
CXB2/ByJ m 39019.0 7063.0   2   4994.0 0.181 34025.0, 44013.0 -1.15
CXB3/ByJ m 129651.0 18679.0   2   13208.0 0.144 116442.0, 142859.0 0.21
CXB4/ByJ m 120490.0 58772.0   2   41558.0 0.488 78932.0, 162048.0 0.07
CXB6/ByJ m 65735.0 42510.0   3 24543.0 0.647 19591.0, 103303.0 -0.75
CXB7/ByJ m 133735.0 39120.0   2   27662.0 0.293 106073.0, 161397.0 0.27
CXB8/HiAJ m 102548.0 34373.0   3 19845.0 0.335 63336.0, 127476.0 -0.2
CXB9/HiAJ m 94344.0 19923.0   3 11503.0 0.211 77784.0, 116454.0 -0.32
DBA/2J m 177371.0 47004.0   4 23502.0 0.265 111489.0, 219145.0 0.92
FVB/NJ m 54714.0 0.0   1   0.0 0.0 54714.0, 54714.0 -0.92
I/LnJ m 148632.0 0.0   1   0.0 0.0 148632.0, 148632.0 0.49
KK/HlJ m 195845.0 0.0   1   0.0 0.0 195845.0, 195845.0 1.2
LG/J m 268126.0 0.0   1   0.0 0.0 268126.0, 268126.0 2.28
LP/J m 200908.0 0.0   1   0.0 0.0 200908.0, 200908.0 1.27
MA/MyJ m 257185.0 0.0   1   0.0 0.0 257185.0, 257185.0 2.12
NOD/ShiLtJ m 62630.0 0.0   1   0.0 0.0 62630.0, 62630.0 -0.8
NON/ShiLtJ m 314643.0 0.0   1   0.0 0.0 314643.0, 314643.0 2.98
NZW/LacJ m 126930.0 0.0   1   0.0 0.0 126930.0, 126930.0 0.17
PL/J m 152755.0 0.0   1   0.0 0.0 152755.0, 152755.0 0.55
RIIIS/J m 85562.0 0.0   1   0.0 0.0 85562.0, 85562.0 -0.45
SEA/GnJ m 92034.0 0.0   1   0.0 0.0 92034.0, 92034.0 -0.36
SJL/J m 98527.0 0.0   1   0.0 0.0 98527.0, 98527.0 -0.26
SM/J m 166604.0 0.0   1   0.0 0.0 166604.0, 166604.0 0.76
SWR/J m 83803.0 0.0   1   0.0 0.0 83803.0, 83803.0 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 126087.9 41303.4884 210220.3527 41955.4473
AXB19b/PgnJ m 151756.15 41303.4884 235888.6027 67623.6973
AXB24/PgnJ m 68289.1 41303.4884 152421.5527 0.0
BALB/cJ m 330499.6667 33724.1571 399193.5267 261805.8067
BXA16/PgnJ m 77868.2 41303.4884 162000.6527 0.0
BXD19/TyJ m 208722.2 41303.4884 292854.6527 124589.7473
BXD28/TyJ m 89616.95 41303.4884 173749.4027 5484.4973
BXH4/TyJ m 96112.75 41303.4884 180245.2027 11980.2973
C3H/HeJ m 215961.3 41303.4884 300093.7527 131828.8473
C57BL/6J m 131140.5 26122.6197 184350.5351 77930.4649
CXB11/HiAJ m 62873.1 41303.4884 147005.5527 0.0
CXB12/HiAJ m 92652.05 41303.4884 176784.5027 8519.5973
CXB13/HiAJ m 138672.4 41303.4884 222804.8527 54539.9473
CXB1/ByJ m 162543.3 33724.1571 231237.16 93849.44
CXB2/ByJ m 39018.65 41303.4884 123151.1027 0.0
CXB3/ByJ m 129650.6 41303.4884 213783.0527 45518.1473
CXB4/ByJ m 120490.15 41303.4884 204622.6027 36357.6973
CXB6/ByJ m 65735.1333 33724.1571 134428.9933 0.0
CXB7/ByJ m 133735.05 41303.4884 217867.5027 49602.5973
CXB8/HiAJ m 102547.8 33724.1571 171241.66 33853.94
CXB9/HiAJ m 94344.3667 33724.1571 163038.2267 25650.5067
DBA/2J m 177371.225 29205.9767 236861.8528 117880.5972




  GWAS USING LINEAR MIXED MODELS