Phenotype measure:   HMDPpheno8   dehydrocholate

ID, description, units MPD:50305   dehydrocholate   12-dehydrocholate (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - 12-dehydrocholate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means341348   None
Median of the strain means269876   None
SD of the strain means± 212945
Coefficient of variation (CV)0.624
Min–max range of strain means39212   –   1081100   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 2591106707526.24 123386033691.726 1.8327 0.0564
Residuals 34 2289046303713.34 67324891285.6864


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 112565.0 0.0   1   0.0 0.0 112565.0, 112565.0 -1.07
A/J m 231876.0 99602.0   2   70429.0 0.43 161447.0, 302305.0 -0.51
AKR/J m 337892.0 0.0   1   0.0 0.0 337892.0, 337892.0 -0.02
AXB10/PgnJ m 297507.0 0.0   1   0.0 0.0 297507.0, 297507.0 -0.21
AXB12/PgnJ m 232700.0 0.0   1   0.0 0.0 232700.0, 232700.0 -0.51
AXB13/PgnJ m 612937.0 0.0   1   0.0 0.0 612937.0, 612937.0 1.28
AXB15/PgnJ m 79023.0 0.0   1   0.0 0.0 79023.0, 79023.0 -1.23
AXB19a/PgnJ m 313158.0 0.0   1   0.0 0.0 313158.0, 313158.0 -0.13
AXB19b/PgnJ m 706007.0 492601.0   2   348322.0 0.698 357685.0, 1054329.0 1.71
AXB19/PgnJ m 201879.0 0.0   1   0.0 0.0 201879.0, 201879.0 -0.65
AXB1/PgnJ m 169840.0 0.0   1   0.0 0.0 169840.0, 169840.0 -0.81
AXB23/PgnJ m 265504.0 0.0   1   0.0 0.0 265504.0, 265504.0 -0.36
AXB24/PgnJ m 143011.0 70024.0   2   49514.0 0.49 93497.0, 192526.0 -0.93
AXB2/PgnJ m 312793.0 0.0   1   0.0 0.0 312793.0, 312793.0 -0.13
AXB4/PgnJ m 315585.0 0.0   1   0.0 0.0 315585.0, 315585.0 -0.12
AXB5/PgnJ m 162496.0 0.0   1   0.0 0.0 162496.0, 162496.0 -0.84
AXB6/PgnJ m 654558.0 0.0   1   0.0 0.0 654558.0, 654558.0 1.47
AXB8/PgnJ m 425395.0 0.0   1   0.0 0.0 425395.0, 425395.0 0.39
BALB/cJ m 818516.0 477730.0   3 275818.0 0.584 414469.0, 1345786.0 2.24
BTBR T+ Itpr3tf/J m 243387.0 0.0   1   0.0 0.0 243387.0, 243387.0 -0.46
BUB/BnJ m 430048.0 0.0   1   0.0 0.0 430048.0, 430048.0 0.42
BXA11/PgnJ m 332440.0 0.0   1   0.0 0.0 332440.0, 332440.0 -0.04
BXA12/PgnJ m 219281.0 0.0   1   0.0 0.0 219281.0, 219281.0 -0.57
BXA13/PgnJ m 237929.0 0.0   1   0.0 0.0 237929.0, 237929.0 -0.49
BXA14/PgnJ m 404960.0 0.0   1   0.0 0.0 404960.0, 404960.0 0.3
BXA16/PgnJ m 233510.0 208751.0   2   147609.0 0.894 85901.0, 381119.0 -0.51
BXA1/PgnJ m 82521.0 0.0   1   0.0 0.0 82521.0, 82521.0 -1.22
BXA24/PgnJ m 438385.0 0.0   1   0.0 0.0 438385.0, 438385.0 0.46
BXA25/PgnJ m 178715.0 0.0   1   0.0 0.0 178715.0, 178715.0 -0.76
BXA26/PgnJ m 342046.0 0.0   1   0.0 0.0 342046.0, 342046.0 0.0
BXA2/PgnJ m 277944.0 0.0   1   0.0 0.0 277944.0, 277944.0 -0.3
BXA4/PgnJ m 49130.0 0.0   1   0.0 0.0 49130.0, 49130.0 -1.37
BXA7/PgnJ m 443374.0 0.0   1   0.0 0.0 443374.0, 443374.0 0.48
BXA8/PgnJ m 442946.0 0.0   1   0.0 0.0 442946.0, 442946.0 0.48
BXD11/TyJ m 445572.0 0.0   1   0.0 0.0 445572.0, 445572.0 0.49
BXD12/TyJ m 136776.0 0.0   1   0.0 0.0 136776.0, 136776.0 -0.96
BXD13/TyJ m 352780.0 0.0   1   0.0 0.0 352780.0, 352780.0 0.05
BXD14/TyJ m 304171.0 0.0   1   0.0 0.0 304171.0, 304171.0 -0.17
BXD15/TyJ m 130739.0 0.0   1   0.0 0.0 130739.0, 130739.0 -0.99
BXD18/TyJ m 187965.0 0.0   1   0.0 0.0 187965.0, 187965.0 -0.72
BXD19/TyJ m 451814.0 176285.0   2   124652.0 0.39 327162.0, 576466.0 0.52
BXD1/TyJ m 174316.0 0.0   1   0.0 0.0 174316.0, 174316.0 -0.78
BXD20/TyJ m 296150.0 0.0   1   0.0 0.0 296150.0, 296150.0 -0.21
BXD21/TyJ m 142473.0 0.0   1   0.0 0.0 142473.0, 142473.0 -0.93
BXD22/TyJ m 199404.0 0.0   1   0.0 0.0 199404.0, 199404.0 -0.67
BXD24/TyJ m 174299.0 0.0   1   0.0 0.0 174299.0, 174299.0 -0.78
BXD24/TyJ-Cep290rd16/J m 199977.0 0.0   1   0.0 0.0 199977.0, 199977.0 -0.66
BXD28/TyJ m 254362.0 79146.0   2   55964.0 0.311 198398.0, 310326.0 -0.41
BXD29-Tlr4lps-2J/J m 243108.0 0.0   1   0.0 0.0 243108.0, 243108.0 -0.46
BXD2/TyJ m 228700.0 0.0   1   0.0 0.0 228700.0, 228700.0 -0.53
BXD32/TyJ m 415100.0 0.0   1   0.0 0.0 415100.0, 415100.0 0.35
BXD33/TyJ m 201142.0 0.0   1   0.0 0.0 201142.0, 201142.0 -0.66
BXD34/TyJ m 527464.0 0.0   1   0.0 0.0 527464.0, 527464.0 0.87
BXD36/TyJ m 214955.0 0.0   1   0.0 0.0 214955.0, 214955.0 -0.59
BXD38/TyJ m 585370.0 0.0   1   0.0 0.0 585370.0, 585370.0 1.15
BXD39/TyJ m 266913.0 0.0   1   0.0 0.0 266913.0, 266913.0 -0.35
BXD40/TyJ m 190772.0 0.0   1   0.0 0.0 190772.0, 190772.0 -0.71
BXD42/TyJ m 109139.0 0.0   1   0.0 0.0 109139.0, 109139.0 -1.09
BXD5/TyJ m 155111.0 0.0   1   0.0 0.0 155111.0, 155111.0 -0.87
BXD6/TyJ m 336207.0 0.0   1   0.0 0.0 336207.0, 336207.0 -0.02
BXD8/TyJ m 121314.0 0.0   1   0.0 0.0 121314.0, 121314.0 -1.03
BXD9/TyJ m 193737.0 0.0   1   0.0 0.0 193737.0, 193737.0 -0.69
BXH10/TyJ m 97995.0 0.0   1   0.0 0.0 97995.0, 97995.0 -1.14
BXH19/TyJ m 560236.0 0.0   1   0.0 0.0 560236.0, 560236.0 1.03
BXH20/KccJ m 272838.0 0.0   1   0.0 0.0 272838.0, 272838.0 -0.32
BXH22/KccJ m 143918.0 0.0   1   0.0 0.0 143918.0, 143918.0 -0.93
BXH2/TyJ m 507981.0 0.0   1   0.0 0.0 507981.0, 507981.0 0.78
BXH4/TyJ m 202823.0 161076.0   2   113898.0 0.794 88925.0, 316721.0 -0.65
BXH6/TyJ m 1054661.0 0.0   1   0.0 0.0 1054661.0, 1054661.0 3.35
BXH7/TyJ m 134470.0 0.0   1   0.0 0.0 134470.0, 134470.0 -0.97
BXH8/TyJ m 239940.0 0.0   1   0.0 0.0 239940.0, 239940.0 -0.48
BXH9/TyJ m 844944.0 0.0   1   0.0 0.0 844944.0, 844944.0 2.36
C3H/HeJ m 212658.0 111992.0   2   79190.0 0.527 133468.0, 291848.0 -0.6
C57BL/6J m 556673.0 230721.0   5 103181.0 0.414 378296.0, 948396.0 1.01
C57L/J m 197878.0 0.0   1   0.0 0.0 197878.0, 197878.0 -0.67
C58/J m 471643.0 0.0   1   0.0 0.0 471643.0, 471643.0 0.61
CAST/EiJ m 79185.0 0.0   1   0.0 0.0 79185.0, 79185.0 -1.23
CBA/J m 175533.0 0.0   1   0.0 0.0 175533.0, 175533.0 -0.78
CE/J m 208417.0 0.0   1   0.0 0.0 208417.0, 208417.0 -0.62
CXB11/HiAJ m 260622.0 159165.0   2   112547.0 0.611 148075.0, 373168.0 -0.38
CXB12/HiAJ m 1081100.0 292770.0   2   207020.0 0.271 874080.0, 1288120.0 3.47
CXB13/HiAJ m 457653.0 205592.0   3 118699.0 0.449 258563.0, 669182.0 0.55
CXB1/ByJ m 533979.0 285093.0   3 164599.0 0.534 318174.0, 857170.0 0.9
CXB2/ByJ m 180182.0 44590.0   3 25744.0 0.247 129945.0, 215072.0 -0.76
CXB3/ByJ m 523470.0 255071.0   2   180362.0 0.487 343108.0, 703832.0 0.86
CXB4/ByJ m 488122.0 72978.0   2   51604.0 0.15 436518.0, 539725.0 0.69
CXB6/ByJ m 630073.0 408298.0   3 235731.0 0.648 276443.0, 1076919.0 1.36
CXB7/ByJ m 398383.0 152017.0   2   107493.0 0.382 290891.0, 505876.0 0.27
CXB8/HiAJ m 582104.0 393125.0   3 226971.0 0.675 164393.0, 944860.0 1.13
CXB9/HiAJ m 433341.0 142709.0   3 82393.0 0.329 270269.0, 535407.0 0.43
DBA/2J m 361753.0 186125.0   4 93063.0 0.515 251540.0, 639647.0 0.1
FVB/NJ m 239544.0 0.0   1   0.0 0.0 239544.0, 239544.0 -0.48
I/LnJ m 450174.0 0.0   1   0.0 0.0 450174.0, 450174.0 0.51
KK/HlJ m 482632.0 0.0   1   0.0 0.0 482632.0, 482632.0 0.66
LG/J m 844978.0 0.0   1   0.0 0.0 844978.0, 844978.0 2.37
LP/J m 538510.0 0.0   1   0.0 0.0 538510.0, 538510.0 0.93
MA/MyJ m 974123.0 0.0   1   0.0 0.0 974123.0, 974123.0 2.97
NOD/ShiLtJ m 212725.0 0.0   1   0.0 0.0 212725.0, 212725.0 -0.6
NON/ShiLtJ m 503035.0 0.0   1   0.0 0.0 503035.0, 503035.0 0.76
NZW/LacJ m 204650.0 0.0   1   0.0 0.0 204650.0, 204650.0 -0.64
PL/J m 495574.0 0.0   1   0.0 0.0 495574.0, 495574.0 0.72
RIIIS/J m 39212.0 0.0   1   0.0 0.0 39212.0, 39212.0 -1.42
SEA/GnJ m 205971.0 0.0   1   0.0 0.0 205971.0, 205971.0 -0.64
SJL/J m 401623.0 0.0   1   0.0 0.0 401623.0, 401623.0 0.28
SM/J m 513217.0 0.0   1   0.0 0.0 513217.0, 513217.0 0.81
SWR/J m 194685.0 0.0   1   0.0 0.0 194685.0, 194685.0 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 231875.85 183473.2832 604738.4224 0.0
AXB19b/PgnJ m 706007.1 183473.2832 1078869.6724 333144.5276
AXB24/PgnJ m 143011.4 183473.2832 515873.9724 0.0
BALB/cJ m 818516.2333 149805.3084 1122957.2488 514075.2178
BXA16/PgnJ m 233510.3 183473.2832 606372.8724 0.0
BXD19/TyJ m 451814.25 183473.2832 824676.8224 78951.6776
BXD28/TyJ m 254362.0 183473.2832 627224.5724 0.0
BXH4/TyJ m 202823.1 183473.2832 575685.6724 0.0
C3H/HeJ m 212657.75 183473.2832 585520.3224 0.0
C57BL/6J m 556672.6 116038.6929 792491.5966 320853.6034
CXB11/HiAJ m 260621.8 183473.2832 633484.3724 0.0
CXB12/HiAJ m 1081100.05 183473.2832 1453962.6224 708237.4776
CXB13/HiAJ m 457652.6333 149805.3084 762093.6488 153211.6178
CXB1/ByJ m 533978.7 149805.3084 838419.7155 229537.6845
CXB2/ByJ m 180182.1667 149805.3084 484623.1822 0.0
CXB3/ByJ m 523469.7 183473.2832 896332.2724 150607.1276
CXB4/ByJ m 488121.85 183473.2832 860984.4224 115259.2776
CXB6/ByJ m 630073.1 149805.3084 934514.1155 325632.0845
CXB7/ByJ m 398383.4 183473.2832 771245.9724 25520.8276
CXB8/HiAJ m 582103.7333 149805.3084 886544.7488 277662.7178
CXB9/HiAJ m 433340.5333 149805.3084 737781.5488 128899.5178
DBA/2J m 361752.8 129735.2027 625406.4534 98099.1466




  GWAS USING LINEAR MIXED MODELS