Phenotype measure:   HMDPpheno8   cholate

ID, description, units MPD:50304   cholate   cholate (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - cholate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means471791   None
Median of the strain means401603   None
SD of the strain means± 290737
Coefficient of variation (CV)0.616
Min–max range of strain means51688   –   1866425   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 11669360028954.9 555683810902.613 2.1421 0.0233
Residuals 34 8819888308199.69 259408479652.932


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 152815.0 0.0   1   0.0 0.0 152815.0, 152815.0 -1.1
A/J m 819407.0 661658.0   2   467863.0 0.807 351545.0, 1287270.0 1.2
AKR/J m 371429.0 0.0   1   0.0 0.0 371429.0, 371429.0 -0.35
AXB10/PgnJ m 444999.0 0.0   1   0.0 0.0 444999.0, 444999.0 -0.09
AXB12/PgnJ m 604245.0 0.0   1   0.0 0.0 604245.0, 604245.0 0.46
AXB13/PgnJ m 427390.0 0.0   1   0.0 0.0 427390.0, 427390.0 -0.15
AXB15/PgnJ m 356710.0 0.0   1   0.0 0.0 356710.0, 356710.0 -0.4
AXB19a/PgnJ m 458440.0 0.0   1   0.0 0.0 458440.0, 458440.0 -0.05
AXB19b/PgnJ m 638243.0 321183.0   2   227111.0 0.503 411132.0, 865354.0 0.57
AXB19/PgnJ m 761932.0 0.0   1   0.0 0.0 761932.0, 761932.0 1.0
AXB1/PgnJ m 192881.0 0.0   1   0.0 0.0 192881.0, 192881.0 -0.96
AXB23/PgnJ m 600222.0 0.0   1   0.0 0.0 600222.0, 600222.0 0.44
AXB24/PgnJ m 370262.0 105290.0   2   74451.0 0.284 295810.0, 444713.0 -0.35
AXB2/PgnJ m 622054.0 0.0   1   0.0 0.0 622054.0, 622054.0 0.52
AXB4/PgnJ m 359618.0 0.0   1   0.0 0.0 359618.0, 359618.0 -0.39
AXB5/PgnJ m 299641.0 0.0   1   0.0 0.0 299641.0, 299641.0 -0.59
AXB6/PgnJ m 751251.0 0.0   1   0.0 0.0 751251.0, 751251.0 0.96
AXB8/PgnJ m 562763.0 0.0   1   0.0 0.0 562763.0, 562763.0 0.31
BALB/cJ m 991138.0 257836.0   3 148862.0 0.26 694001.0, 1155887.0 1.79
BTBR T+ Itpr3tf/J m 363938.0 0.0   1   0.0 0.0 363938.0, 363938.0 -0.37
BUB/BnJ m 858928.0 0.0   1   0.0 0.0 858928.0, 858928.0 1.33
BXA11/PgnJ m 995269.0 0.0   1   0.0 0.0 995269.0, 995269.0 1.8
BXA12/PgnJ m 164790.0 0.0   1   0.0 0.0 164790.0, 164790.0 -1.06
BXA13/PgnJ m 501464.0 0.0   1   0.0 0.0 501464.0, 501464.0 0.1
BXA14/PgnJ m 863429.0 0.0   1   0.0 0.0 863429.0, 863429.0 1.35
BXA16/PgnJ m 270364.0 77140.0   2   54546.0 0.285 215817.0, 324910.0 -0.69
BXA1/PgnJ m 258934.0 0.0   1   0.0 0.0 258934.0, 258934.0 -0.73
BXA24/PgnJ m 885634.0 0.0   1   0.0 0.0 885634.0, 885634.0 1.42
BXA25/PgnJ m 259250.0 0.0   1   0.0 0.0 259250.0, 259250.0 -0.73
BXA26/PgnJ m 295406.0 0.0   1   0.0 0.0 295406.0, 295406.0 -0.61
BXA2/PgnJ m 469750.0 0.0   1   0.0 0.0 469750.0, 469750.0 -0.01
BXA4/PgnJ m 51688.0 0.0   1   0.0 0.0 51688.0, 51688.0 -1.44
BXA7/PgnJ m 821213.0 0.0   1   0.0 0.0 821213.0, 821213.0 1.2
BXA8/PgnJ m 513942.0 0.0   1   0.0 0.0 513942.0, 513942.0 0.14
BXD11/TyJ m 790381.0 0.0   1   0.0 0.0 790381.0, 790381.0 1.1
BXD12/TyJ m 324857.0 0.0   1   0.0 0.0 324857.0, 324857.0 -0.51
BXD13/TyJ m 544239.0 0.0   1   0.0 0.0 544239.0, 544239.0 0.25
BXD14/TyJ m 337506.0 0.0   1   0.0 0.0 337506.0, 337506.0 -0.46
BXD15/TyJ m 334955.0 0.0   1   0.0 0.0 334955.0, 334955.0 -0.47
BXD18/TyJ m 333086.0 0.0   1   0.0 0.0 333086.0, 333086.0 -0.48
BXD19/TyJ m 857108.0 363630.0   2   257125.0 0.424 599983.0, 1114233.0 1.33
BXD1/TyJ m 505957.0 0.0   1   0.0 0.0 505957.0, 505957.0 0.12
BXD20/TyJ m 164898.0 0.0   1   0.0 0.0 164898.0, 164898.0 -1.06
BXD21/TyJ m 212282.0 0.0   1   0.0 0.0 212282.0, 212282.0 -0.89
BXD22/TyJ m 202370.0 0.0   1   0.0 0.0 202370.0, 202370.0 -0.93
BXD24/TyJ m 371570.0 0.0   1   0.0 0.0 371570.0, 371570.0 -0.34
BXD24/TyJ-Cep290rd16/J m 478240.0 0.0   1   0.0 0.0 478240.0, 478240.0 0.02
BXD28/TyJ m 256514.0 23848.0   2   16863.0 0.093 239650.0, 273377.0 -0.74
BXD29-Tlr4lps-2J/J m 285566.0 0.0   1   0.0 0.0 285566.0, 285566.0 -0.64
BXD2/TyJ m 226696.0 0.0   1   0.0 0.0 226696.0, 226696.0 -0.84
BXD32/TyJ m 1340189.0 0.0   1   0.0 0.0 1340189.0, 1340189.0 2.99
BXD33/TyJ m 233372.0 0.0   1   0.0 0.0 233372.0, 233372.0 -0.82
BXD34/TyJ m 420067.0 0.0   1   0.0 0.0 420067.0, 420067.0 -0.18
BXD36/TyJ m 349958.0 0.0   1   0.0 0.0 349958.0, 349958.0 -0.42
BXD38/TyJ m 664740.0 0.0   1   0.0 0.0 664740.0, 664740.0 0.66
BXD39/TyJ m 209964.0 0.0   1   0.0 0.0 209964.0, 209964.0 -0.9
BXD40/TyJ m 408241.0 0.0   1   0.0 0.0 408241.0, 408241.0 -0.22
BXD42/TyJ m 160621.0 0.0   1   0.0 0.0 160621.0, 160621.0 -1.07
BXD5/TyJ m 420638.0 0.0   1   0.0 0.0 420638.0, 420638.0 -0.18
BXD6/TyJ m 401769.0 0.0   1   0.0 0.0 401769.0, 401769.0 -0.24
BXD8/TyJ m 182332.0 0.0   1   0.0 0.0 182332.0, 182332.0 -1.0
BXD9/TyJ m 245044.0 0.0   1   0.0 0.0 245044.0, 245044.0 -0.78
BXH10/TyJ m 507569.0 0.0   1   0.0 0.0 507569.0, 507569.0 0.12
BXH19/TyJ m 412548.0 0.0   1   0.0 0.0 412548.0, 412548.0 -0.2
BXH20/KccJ m 378036.0 0.0   1   0.0 0.0 378036.0, 378036.0 -0.32
BXH22/KccJ m 332061.0 0.0   1   0.0 0.0 332061.0, 332061.0 -0.48
BXH2/TyJ m 401437.0 0.0   1   0.0 0.0 401437.0, 401437.0 -0.24
BXH4/TyJ m 321922.0 248829.0   2   175948.0 0.773 145974.0, 497871.0 -0.52
BXH6/TyJ m 1109870.0 0.0   1   0.0 0.0 1109870.0, 1109870.0 2.19
BXH7/TyJ m 243522.0 0.0   1   0.0 0.0 243522.0, 243522.0 -0.79
BXH8/TyJ m 435772.0 0.0   1   0.0 0.0 435772.0, 435772.0 -0.12
BXH9/TyJ m 728437.0 0.0   1   0.0 0.0 728437.0, 728437.0 0.88
C3H/HeJ m 875026.0 198903.0   2   140646.0 0.227 734381.0, 1015672.0 1.39
C57BL/6J m 1866425.0 1361219.0   5 608756.0 0.729 509116.0, 3320204.0 4.8
C57L/J m 251020.0 0.0   1   0.0 0.0 251020.0, 251020.0 -0.76
C58/J m 888793.0 0.0   1   0.0 0.0 888793.0, 888793.0 1.43
CAST/EiJ m 344908.0 0.0   1   0.0 0.0 344908.0, 344908.0 -0.44
CBA/J m 251731.0 0.0   1   0.0 0.0 251731.0, 251731.0 -0.76
CE/J m 183047.0 0.0   1   0.0 0.0 183047.0, 183047.0 -0.99
CXB11/HiAJ m 403018.0 7857.0   2   5555.0 0.0195 397462.0, 408573.0 -0.24
CXB12/HiAJ m 587711.0 348132.0   2   246167.0 0.592 341544.0, 833878.0 0.4
CXB13/HiAJ m 336189.0 92390.0   3 53341.0 0.275 258712.0, 438441.0 -0.47
CXB1/ByJ m 725675.0 67922.0   3 39215.0 0.0936 651159.0, 784118.0 0.87
CXB2/ByJ m 201010.0 24430.0   3 14105.0 0.122 179877.0, 227759.0 -0.93
CXB3/ByJ m 341095.0 124870.0   2   88296.0 0.366 252799.0, 429392.0 -0.45
CXB4/ByJ m 174782.0 4501.0   2   3182.0 0.0257 171600.0, 177964.0 -1.02
CXB6/ByJ m 533244.0 333110.0   3 192321.0 0.625 187201.0, 851706.0 0.21
CXB7/ByJ m 535099.0 205281.0   2   145155.0 0.384 389944.0, 680254.0 0.22
CXB8/HiAJ m 246409.0 126076.0   3 72790.0 0.512 170819.0, 391953.0 -0.78
CXB9/HiAJ m 305054.0 61553.0   3 35538.0 0.202 254228.0, 373494.0 -0.57
DBA/2J m 418538.0 71187.0   4 35594.0 0.17 311881.0, 458533.0 -0.18
FVB/NJ m 305542.0 0.0   1   0.0 0.0 305542.0, 305542.0 -0.57
I/LnJ m 523051.0 0.0   1   0.0 0.0 523051.0, 523051.0 0.18
KK/HlJ m 618908.0 0.0   1   0.0 0.0 618908.0, 618908.0 0.51
LG/J m 889965.0 0.0   1   0.0 0.0 889965.0, 889965.0 1.44
LP/J m 432168.0 0.0   1   0.0 0.0 432168.0, 432168.0 -0.14
MA/MyJ m 1279348.0 0.0   1   0.0 0.0 1279348.0, 1279348.0 2.78
NOD/ShiLtJ m 159417.0 0.0   1   0.0 0.0 159417.0, 159417.0 -1.07
NON/ShiLtJ m 183807.0 0.0   1   0.0 0.0 183807.0, 183807.0 -0.99
NZW/LacJ m 490362.0 0.0   1   0.0 0.0 490362.0, 490362.0 0.06
PL/J m 395990.0 0.0   1   0.0 0.0 395990.0, 395990.0 -0.26
RIIIS/J m 202858.0 0.0   1   0.0 0.0 202858.0, 202858.0 -0.93
SEA/GnJ m 484156.0 0.0   1   0.0 0.0 484156.0, 484156.0 0.04
SJL/J m 260079.0 0.0   1   0.0 0.0 260079.0, 260079.0 -0.73
SM/J m 666789.0 0.0   1   0.0 0.0 666789.0, 666789.0 0.67
SWR/J m 154840.0 0.0   1   0.0 0.0 154840.0, 154840.0 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 819407.4 360144.7484 1551309.5876 87505.2124
AXB19b/PgnJ m 638243.1 360144.7484 1370145.2876 0.0
AXB24/PgnJ m 370261.6 360144.7484 1102163.7876 0.0
BALB/cJ m 991138.1667 294056.9557 1588733.8004 393542.5329
BXA16/PgnJ m 270363.5 360144.7484 1002265.6876 0.0
BXD19/TyJ m 857108.2 360144.7484 1589010.3876 125206.0124
BXD28/TyJ m 256513.6 360144.7484 988415.7876 0.0
BXH4/TyJ m 321922.45 360144.7484 1053824.6376 0.0
C3H/HeJ m 875026.5 360144.7484 1606928.6876 143124.3124
C57BL/6J m 1866425.04 227775.5385 2329320.6274 1403529.4526
CXB11/HiAJ m 403017.6 360144.7484 1134919.7876 0.0
CXB12/HiAJ m 587711.25 360144.7484 1319613.4376 0.0
CXB13/HiAJ m 336189.0 294056.9557 933784.6337 0.0
CXB1/ByJ m 725675.3333 294056.9557 1323270.9671 128079.6996
CXB2/ByJ m 201009.9667 294056.9557 798605.6004 0.0
CXB3/ByJ m 341095.05 360144.7484 1072997.2376 0.0
CXB4/ByJ m 174782.1 360144.7484 906684.2876 0.0
CXB6/ByJ m 533243.7333 294056.9557 1130839.3671 0.0
CXB7/ByJ m 535098.75 360144.7484 1267000.9376 0.0
CXB8/HiAJ m 246409.4 294056.9557 844005.0337 0.0
CXB9/HiAJ m 305053.6667 294056.9557 902649.3004 0.0
DBA/2J m 418537.875 254660.7938 936070.875 0.0




  GWAS USING LINEAR MIXED MODELS